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ANP 1-28, HUMAN

ANP 1-28, HUMAN structure

CAS No.: 89213-87-6

Chemical Name:: ANP 1-28, HUMAN

Synonyms: Carperitide;ATRIAL NATRIURETIC PEPTIDE HUMAN;SLRRSSCFGGRMDRIGAQSGLGCNSFRY;ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, PORCINE);HANF;α-hANP;carperitida;ANP HUMAN, 1-28;ANP 1-28, HUMAN;ANF 1-28, HUMAN

CBNumber:: CB9116087

Molecular Formula:: C127H203N45O39S3

Molecular Weight:: 3080.44

MDL Number:: MFCD00076226

MOL File:: 89213-87-6.mol

Last updated:2025-08-20 16:56:27

Product description	Number	Pack Size	Price
Atrial Natriuretic Peptide (1-28) (human) (trifluoroacetate salt) ≥95%	24539	1mg	$384
AtrialNatriureticFactor(1-28)(human,porcine)	1906	1	$367
Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)	FA110233	500ug	$100
Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)	FA110233	5mg	$602
Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)	FA110233	10mg	$1047
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ANP 1-28, HUMAN Properties

Density	1.55±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Water: 1 mg/ml
form	A lyophilized powder
Sequence	H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH，(Disulfide bridge: Cys-Cys)
InChIKey	NSQLIUXCMFBZME-VUEHYBQXNA-N
FDA UNII	GZ8FA500J0

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H361
Precautionary statements	P201-P202-P281-P308+P313-P405-P501

ANP 1-28, HUMAN price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	24539	Atrial Natriuretic Peptide (1-28) (human) (trifluoroacetate salt) ≥95%	89213-87-6	1mg	$384	2024-03-01	Buy
Tocris	1906	AtrialNatriureticFactor(1-28)(human,porcine)	89213-87-6	1	$367	2021-12-16	Buy
Biosynth Carbosynth	FA110233	Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)	89213-87-6	500ug	$100	2021-12-16	Buy
Biosynth Carbosynth	FA110233	Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)	89213-87-6	5mg	$602	2021-12-16	Buy
Biosynth Carbosynth	FA110233	Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)	89213-87-6	10mg	$1047	2021-12-16	Buy

Product number	Packaging	Price	Buy
24539	1mg	$384	Buy
1906	1	$367	Buy
FA110233	500ug	$100	Buy
FA110233	5mg	$602	Buy
FA110233	10mg	$1047	Buy

ANP 1-28, HUMAN Chemical Properties,Uses,Production

Description

Carperitide is the α-human atrial natriuretic peptide (α-hANP) produced by recombinant technology. It was introduced in Japan as a treatment for acute congestive heart failure (CHF). In dogs with CHF, carperitide significantly reduced the elevated left ventricular end-diastolic pressure and the index of myocardial oxygen consumption (systolic blood pressure x heart rate). In a clinical trial, carperitide was effective in improving hemodynamics and symptoms in 60% of patients with acute CHF. Carperitide was reported to be well tolerated with no significant adverse effects clinically. A beneficial effect on hemodynamics has been reported in chronic heart failure patients. Carperitide is also in clinical trials for maintenance of blood pressure during surgical operations.

Description

Atrial natriuretic peptide (ANP) is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, inhibit renin secretion, and increase sodium excretion. Human ANP binds to ANP receptors on cultured vascular smooth muscle cells (VSMCs) with a K_d value of approximately 1-2 nM and increases cGMP levels in a dose-dependent manner. It relaxes potassium-induced contraction of isolated canine renal arterial strips when used at concentrations of 10 and 100 ng/ml and dilates renal arteries in anesthetized dogs when used at doses ranging from 10 to 100 ng/kg. In a rat model of heart failure following experimental autoimmune myocarditis, human ANP, via osmotic mini pump for 28 days, decreases cardiomyocyte size as well as the amount of cardiac fibrosis and left ventricular remodeling. ANP (1-28) (human) is a 28 amino acid peptide corresponding to the human protein sequence.

Originator

Suntory (Japan)

Uses

Treatment of decompensated congestive heart failure.

Definition

ChEBI: Carperitide is a polypeptide.

brand name

Daiichi Suntory, Japan.

References

[1] T.GEOFFREY FLYNN Adolfo J de B Mercedes L de Bold. The amino acid sequence of an atrial peptide with potent diuretic and natriuretic properties[J]. Biochemical and biophysical research communications, 1983, 117 3: Pages 859-865. DOI: 10.1016/0006-291x(83)91675-3
[2] MAACK T. Role of atrial natriuretic factor in volume control[J]. Kidney international, 1996, 49 6: Pages 1732-1737. DOI: 10.1038/ki.1996.257
[3] YUKIO HIRATA. Specific receptors for atrial natriuretic factor (ANF) in cultured vascular smooth muscle cells of rat aorta[J]. Biochemical and biophysical research communications, 1984, 125 2: Pages 562-568. DOI: 10.1016/0006-291x(84)90576-x
[4] T. ISHIHARA. Vasodilatory and diuretic actions of α-human atrial natriuretic polypeptide (α-hANP)[J]. Life sciences, 1985, 36 12: Pages 1205-1215. DOI: 10.1016/0024-3205(85)90239-5
[5] KOMEI TANAKA. Long-term carperitide treatment attenuates left ventricular remodeling in rats with heart failure after autoimmune myocarditis.[J]. Journal of Cardiovascular Pharmacology, 2009: 232-239. DOI: 10.1097/fjc.0b013e3181b0cf50

ANP 1-28, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

ANP 1-28, HUMAN Suppliers

Global( 145)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8615965530500	nickzhang@hangyubiotech.com	China	8497	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	615	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	995	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	19282	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Nantong Guangyuan Chemicl Co,Ltd	58
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Cellmano Biotech Limited	58
CONIER CHEM AND PHARMA LIMITED	58
Dideu Industries Group Limited	58

View Lastest Price from ANP 1-28, HUMAN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-02-13	Carperitide 89213-87-6	US $0.00 / g	1g	98%min	1000g	WUHAN FORTUNA CHEMICAL CO., LTD
2025-06-20	ANP 1-28, HUMAN 89213-87-6	US $40.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.
2025-06-03	ANP 1-28, HUMAN 89213-87-6	US $80.00-800.00 / kg	10kg	0.99	20tons	Zibo Hangyu Biotechnology Development Co., Ltd

Carperitide
89213-87-6
US $0.00 / g
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

ANP 1-28, HUMAN
89213-87-6
US $40.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

ANP 1-28, HUMAN
89213-87-6
US $80.00-800.00 / kg
0.99
Zibo Hangyu Biotechnology Development Co., Ltd

89213-87-6(ANP 1-28, HUMAN)Related Search:

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PENTAGLYCINE H-ALA-ALA-ALA-TYR-OH H-ALA-ALA-ALA-ALA-ALA-ALA-OH AC-MET-NH2 N-ACETYL-ALA-ALA-ALA

3-[(3-AMINO-3-OXOPROPYL)DITHIO]PROPANAMIDE H-ALA-ALA-TYR-OH URODILATIN HUMAN AC-ILE-NHME H-ALA-ALA-ALA-ALA-OH

H-ARG-MET-NH2 ACETATE SALT GLY-ALA-TYR H-GLY-GLY-BETA-ALA-OH

1of4

ATRIAL NATRIURETIC PEPTIDE HUMAN SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR[SLRRSSCFGGR-MET: O-DRIGAQSGLGCNSFRY]DISULFIDE BRIDGE CYS7-CYS23. Carperitide Acetate, carperitida Atrial Natriuretic Peptide (1-28) (human) (trifluoroacetate salt) ahANF, Carperitide H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH Atrial natriureticpeptide-28 (huMan) (9CI) Atrial Natriuretic Factor (1-28) (huMan) αhANF, Carperitide Carperitide Acetate Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond) ATRIAL NATRIURETIC PEPTIDE HUMAN, 1-28 ATRIAL NATRIURETIC PEPTIDE 1-28, HUMAN ATRIAL NATRIURETIC PEPTIDE (1-28), HUMAN, PORCINE ATRIAL NATRIURETIC FACTOR 1-28, HUMAN ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, CANINE) ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, PORCINE) ANP, ALPHA-, HUMAN ANP HUMAN, 1-28 ANP (HUMAN, 1-28) (PORCINE, BOVINE, CANINE) ANP 1-28, HUMAN ANF 1-28, HUMAN ANF (1-28), HUMAN, PORCINE SLRRSSCFGGRMDRIGAQSGLGCNSFRY SLRRSSCFGGRMDRIGAQSGLGCNSFRY (DISULFIDE BRIDGE: 7-23) SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET(O)-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR Carperitide [MET(O)12]-A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28) [MET(O)12]-ANP (HUMAN, 1-28) atrial natriuretic factor (99-126) ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN, RECOMBINANT ALPHA-ANP [1-28] HUMAN, CANINE ALPHA-ANF (1-28), HUMAN ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN H-SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR-OH (DISULFIDE BRIDGE: 7-23) HANF A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28) (PORCINE, BOVINE, CANINE) ATRIAL NATRIURETIC PEPTIDE, ALPHA-, HUMAN Atrial natriuretic factor【human】 Atrial natriuretic peptide【porcine】 α-Atriopeptin【human】 α-hANP Carperitide / Carperitide Acetate L-Tyrosine, L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-, cyclic (7→23)-disulfi... Carperitide(ANP(1-28)/human) Carperitide impurity ANP 1-28, HUMAN USP/EP/BP Atrial Natriuretic Factor (1-28) (human), αhANF, Carperitide carperitida Carperitide?Acetate (alpha-human atrial natriuretic peptide) 89213-87-6 Biochemicals and Reagents Amino Acids and Peptides BioChemical Peptides Natriuretic Peptides peptide