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(S)-3-phenylmorpholine

(S)-3-phenylmorpholine Structure
(S)-3-phenylmorpholine structure
CAS No.
914299-79-9
Chemical Name:
(S)-3-phenylmorpholine
Synonyms
(S)-3-phenylmorpholine;(S)-4-Phenylmorpholine;(3S)-3-phenylmorpholine;Morpholine, 3-phenyl-, (3S)-
CBNumber:
CB91166254
Molecular Formula:
C10H13NO
Molecular Weight:
163.22
MDL Number:
MFCD11016232
MOL File:
914299-79-9.mol
MSDS File:
SDS
Last updated:2026-05-28 03:44:47
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(S)-3-phenylmorpholine Properties

storage temp. Keep in dark place,Inert atmosphere,Room temperature
Appearance Off-white to light yellow Solid
optical activity 44.9069°(C=1.0038g/ml MEOH)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

(S)-3-phenylmorpholine price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS3692-A-3S (3S)-3-Phenyl-morpholine 98%EE 914299-79-9 1g $264 2026-06-04 Buy
Activate Scientific AS3692-A-3S (3S)-3-Phenyl-morpholine 98%EE 914299-79-9 5g $830 2026-06-04 Buy
Synthonix P61270 (S)-3-Phenylmorpholine >98% 914299-79-9 100mg $25 2026-05-06 Buy
Synthonix P61270 (S)-3-Phenylmorpholine >98% 914299-79-9 250mg $30 2026-05-06 Buy
Synthonix P61270 (S)-3-Phenylmorpholine >98% 914299-79-9 1g $70 2026-05-06 Buy
Product number Packaging Price Buy
AS3692-A-3S 1g $264 Buy
AS3692-A-3S 5g $830 Buy
P61270 100mg $25 Buy
P61270 250mg $30 Buy
P61270 1g $70 Buy

(S)-3-phenylmorpholine Chemical Properties,Uses,Production

Synthesis

(5S)-5-Phenyl-3-morpholinone

1052209-96-7

(S)-3-phenylmorpholine

914299-79-9

Step 3. A THF solution of (S)-5-phenylmorpholin-3-one (481 mg, dissolved in 6 mL of THF) was slowly added dropwise to a LiAlH4/THF suspension (0.47 g LiAlH4 dissolved in 2 mL of THF) at room temperature for a controlled time of over 5 minutes. After the dropwise addition, the reaction mixture was stirred at room temperature for 1 h, followed by transferring to a 72 °C oil bath for heating overnight. Upon completion of the reaction, the mixture was cooled to 0 °C and the reaction was quenched by sequential addition of H2O (0.47 mL), 3M NaOH aqueous solution (0.47 mL) and H2O (1.4 mL). The quenched mixture was diluted with Et2O (30 mL) and stirred for 10 min before separating the ether phase by filtration. The filtrate was concentrated and further dried under vacuum to give (S)-3-phenylmorpholine as a colorless solid (424 mg, 96% yield).LCMS (m/z): 164.2 (MH+), retention time 0.33 min.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 15, p. 4316 - 4320
[2] Angewandte Chemie - International Edition, 2013, vol. 52, # 20, p. 5319 - 5322
[3] Angew. Chem., 2013, vol. 125, # 20, p. 5427 - 5430,4
[4] Patent: US9242996, 2016, B2. Location in patent: Page/Page column 265; 266
[5] Patent: WO2018/116285, 2018, A1. Location in patent: Page/Page column 24

(S)-3-phenylmorpholine Preparation Products And Raw materials

Raw materials

(5S)-5-Phenyl-3-morpholinone Morpholine, 4-[(4-methylphenyl)sulfonyl]-3-phenyl-, (3S)- Phenol Lithium Aluminum Hydride Tetrahydrofuran

Preparation Products

(S)-3-phenylmorpholine Suppliers

Global( 73)Suppliers
Supplier Tel Email Country ProdList Advantage
ForeChem (Nantong) Technology Co.,Ltd. 513-85982855 18921614129 sales@xianxingpharm.com China 2712 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Cuisen Pharmaceutical Technology Co., Ltd. 13472757003 yongnan.wang@cendrix.cn China 971 65
Shijiazhuang Lickon PharmaTech Co., Ltd. 031185291771 13832391721 yaofeng2005@163.com China 947 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Chengdu Firster Pharmaceutical Co., Ltd. 028-87078428 028-87074958 chengzhenyong@cdfirster.com China 2580 60
Shanghai Balmxy Pharmaceutical Co., Ltd 021-24206007 13764915196 sales@balmxy.com China 6959 55
LABTER PHARMATECH(BEIJING) CO.,LTD 010-56330744 18310155299 sales@labter.com.cn China 19999 55
AN PharmaTech Co Ltd 86(21)68097365 sales@anpharma.net China 4875 55
Supplier Advantage
ForeChem (Nantong) Technology Co.,Ltd. 61
Capot Chemical Co., Ltd 66
Shanghai Longsheng chemical Co.,Ltd. 59
Shanghai Cuisen Pharmaceutical Technology Co., Ltd. 65
Shijiazhuang Lickon PharmaTech Co., Ltd. 58
Bide Pharmatech Ltd. 60
Chengdu Firster Pharmaceutical Co., Ltd. 60
Shanghai Balmxy Pharmaceutical Co., Ltd 55
LABTER PHARMATECH(BEIJING) CO.,LTD 55
AN PharmaTech Co Ltd 55

View Lastest Price from (S)-3-phenylmorpholine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-3-phenylmorpholine pictures 2019-09-04 (S)-3-phenylmorpholine
914299-79-9
 $5.00 1KG 95%-98% 100kg Career Henan Chemical Co

(S)-3-phenylmorpholine Spectrum

(S)-3-phenylmorpholine(914299-79-9)1HNMR

914299-79-9((S)-3-phenylmorpholine)Related Search:

3S-3-METHYLMORPHOLINE (S)-3-(tert-butyl)morpholine (R)-3-BENZYLMORPHOLINE (R)-3-ISOPROPYLMORPHOLINE, (S)-3-((S)-sec-butyl)Morpholine
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Fosaprepitant (5S)-3,4,5,6-TETRAHYDRO-5-PHENYL-N-(BENZYLOXYCARBONYL)-4(H)-1,4-OXAZIN-2-ONE (2R,6R,8S,12S)-1-AZA-10-OXA-12-PHENYLTRICYCLO[6.4.01,8.02,6]DODECAN-9-ONE

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(S)-3-phenylmorpholine Morpholine, 3-phenyl-, (3S)- (3S)-3-phenylmorpholine (S)-4-Phenylmorpholine 914299-79-9