L-Pyroglutamamide
- CAS No.
- 16395-57-6
- Chemical Name:
- L-Pyroglutamamide
- Synonyms
- L-PYROGLUTAMAMIDE;5-oxo-l-prolamide;5-Oxo-L-prolinamide;L-Pyroglutamamide USP/EP/BP;(2S)-5-oxopyrrolidine-2-carboxamide;(2S)-5-Oxo-2α-pyrrolidinecarboxamide;2-Pyrrolidinecarboxamide, 5-oxo-, (2S)-
- CBNumber:
- CB9117923
- Molecular Formula:
- C5H8N2O2
- Molecular Weight:
- 128.13
- MDL Number:
- MFCD00037888
- MOL File:
- 16395-57-6.mol
- MSDS File:
- SDS
| Melting point | 148-150 °C(Solv: methanol (67-56-1)) |
|---|---|
| Boiling point | 515.9±39.0 °C(Predicted) |
| Density | 1.285±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 14.90±0.40(Predicted) |
| Appearance | White to off-white Solid |
| optical activity | Consistent with structure |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H225 |
| Precautionary statements | P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235 |
L-Pyroglutamamide price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA00HYZQ | (S);-5-Oxopyrrolidine-2-carboxamide 95% | 16395-57-6 | 100mg | $8 | 2026-05-29 | Buy |
| aablocks | AA00HYZQ | (S);-5-Oxopyrrolidine-2-carboxamide 95% | 16395-57-6 | 250mg | $12 | 2026-05-29 | Buy |
| aablocks | AA00HYZQ | (S);-5-Oxopyrrolidine-2-carboxamide 95% | 16395-57-6 | 1g | $24 | 2026-05-29 | Buy |
| aablocks | AA00HYZQ | (S);-5-Oxopyrrolidine-2-carboxamide 95% | 16395-57-6 | 5g | $74 | 2026-05-29 | Buy |
| ACHEMBLOCK | W162264 | (S)-5-Oxopyrrolidine-2-carboxamide 97% | 16395-57-6 | 5G | $120 | 2026-05-27 | Buy |
L-Pyroglutamamide Chemical Properties,Uses,Production
Synthesis
4931-66-2
16395-57-6
GENERAL METHOD: L-Pyroglutamic acid methyl ester (10 mmol) was dissolved in a mixed NH3[aq]/N2H4[aq] solution (50 mL) at room temperature and the reaction was stirred for 12 hours. Subsequently, the reaction mixture was allowed to stand at -10 °C for 24 h to promote crystallization. The resulting crystals were washed sequentially with ethanol and ether and dried with anhydrous MgSO4. The crude product was purified by fast column chromatography on silica gel with the eluent methanol/dichloromethane (1:6, v/v), resulting in the pure (S)-5-oxopyrrolidine-2-carboxamide in white solid form.
References
[1] Tetrahedron, 1995, vol. 51, # 3, p. 801 - 810
[2] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 16, p. 4644 - 4649
L-Pyroglutamamide Preparation Products And Raw materials
L-Pyroglutamamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Balmxy Pharmaceutical Co., Ltd | 021-24206007 13764915196 | sales@balmxy.com | China | 6959 | 55 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Nanjing XiZe Biotechnology CO., Ltd. | 025-66023220 15250997978 | 1511893459@qq.com | China | 4777 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shandong Ono Chemical Co., Ltd. | 0539-6362799 20） | China | 9998 | 58 | |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22344 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
View Lastest Price from L-Pyroglutamamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | (S)-5-Oxopyrrolidine-2-carboxamide
16395-57-6
|
$1.00 | 1g | ≥98% | Career Henan Chemical Co |
-
- (S)-5-Oxopyrrolidine-2-carboxamide
16395-57-6
- $1.00
- ≥98%
- Career Henan Chemical Co
