Taurochenodeoxycholic acid
- CAS No.
- 516-35-8
- Chemical Name:
- Taurochenodeoxycholic acid
- Synonyms
- TCDCA;C05465;Chenyltaurine;12-Deoxycholyltaurine;Taurochenodeoxycholic;12-Desoxycholyltaurine;Chenodeoxycholyltaurine;aurochenodeoxycholicaci;Chenodeoxycholoyltaurine;Taurochenodeoxycholic acid
- CBNumber:
- CB91236274
- Molecular Formula:
- C26H45NO6S
- Molecular Weight:
- 499.7
- MDL Number:
- MFCD00232922
- MOL File:
- 516-35-8.mol
| Melting point | 186-200°C |
|---|---|
| Density | 1.216±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol |
| form | Solid |
| pka | 1.42±0.50(Predicted) |
| color | White to Pale Beige |
| InChIKey | BHTRKEVKTKCXOH-ZNKJZDQHNA-N |
| SMILES | [C@@]12([H])CC[C@H]([C@H](C)CCC(=O)NCCS(=O)(=O)O)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@@H](O)C[C@@]3([H])C[C@@H](O)[C@@]21[H] |&1:0,4,5,18,22,24,28,31,34,36,r| |
| FDA UNII | 651KU15938 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P240-P241-P242-P243-P260-P264-P270-P271-P280-P301+P310-P321-P330-P303+P361+P353-P304+P340-P307+P311-P312-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
Taurochenodeoxycholic acid price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-6329 | Taurochenodeoxycholicacid 99.80% | 516-35-8 | 50mg | $60 | 2021-12-16 | Buy |
| IsoSciences | 13105UNL | TaurochenodeoxycholicAcidSodiumSalt ≥98% | 516-35-8 | 50mg | $109 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb105250 | Taurochenodeoxycholic Acid >98%,Standard References Grade | 516-35-8 | 20mg | $569.5 | 2021-12-16 | Buy |
| Matrix Scientific | 095142 | Taurochenodesoxycholic acid 95+% | 516-35-8 | 1g | $665 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0000616 | TAUROCHENODEOXYCHOLIC ACID 95.00% | 516-35-8 | 100MG | $750.75 | 2021-12-16 | Buy |
Taurochenodeoxycholic acid Chemical Properties,Uses,Production
Uses
Taurochenodeoxycholic Acid is a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.
Uses
Labelled analogue of Taurochenodeoxycholic Acid, a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.
Definition
ChEBI: A bile acid taurine conjugate of chenodeoxycholic acid.
in vivo
Taurochenodeoxycholic acid (12-Deoxycholyltaurine; 0.05, 0.1g/kg) decreases the pulmonary coefficient in the model mice and reduces the pathological damages on their lungs; it can decrease the expression levels of TNF-α and TIMP-2 in pulmonary tissues in the pulmonary fibrosis mice and has no significant effects on MMP2[2].
?
Taurochenodeoxycholic acid significantly normalizes the clinical inflammatory parameters, prevented indomethacin-induced increases in the biliary contents of secondary bile acids and hydrophobicity index, and tended to attenuate the intestinal inflammation[3].
?
Taurochenodeoxycholic acid significantly suppresses paw swelling and polyarthritis index, increases the loss body weight and index of thymus and spleen, and amends radiologic changes in AA rats. The overproduction and mRNA expression of TNF-α, IL-1β and IL-6 are remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats[4].
IC 50
Microbial Metabolite; Human Endogenous Metabolite
Taurochenodeoxycholic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8367 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 +86-13986145403; | info@fortunachem.com | China | 5987 | 58 |
| Anhuyan (Hainan) Biotechnology Co., LTD | +86-18163349544; +8618163349544 | mollylucking@foxmail.com | China | 3000 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3969 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12151 | 58 |
View Lastest Price from Taurochenodeoxycholic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-08 | Taurochenodeoxycholic acid
516-35-8
|
US $137.00 / g | 1g | 0.99 | 25kg | Shanghai UCHEM Inc. | |
 |
2025-09-30 | Taurochenodeoxycholic Acid
516-35-8
|
US $39.00-89.00 / mg | 99.53% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-09-30 | Taurochenodeoxycholic acid
516-35-8
|
US $30.00 / kg | 1kg | 99.99 | 1000000 | Anhuyan (Hainan) Biotechnology Co., LTD |
-
- Taurochenodeoxycholic acid
516-35-8
- US $137.00 / g
- 0.99
- Shanghai UCHEM Inc.
-
- Taurochenodeoxycholic Acid
516-35-8
- US $39.00-89.00 / mg
- 99.53%
- TargetMol Chemicals Inc.
-
- Taurochenodeoxycholic acid
516-35-8
- US $30.00 / kg
- 99.99
- Anhuyan (Hainan) Biotechnology Co., LTD
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