Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI)

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI)

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) Structure
5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) structure
CAS No.
115012-09-4
Chemical Name:
5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI)
Synonyms
6,7-dihydro-7-hydroxy-5H-Pyrrolo[3,4-b]pyridin-5-one;7-Hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one;5H-Pyrrolo[3,4-b]pyridin-5-one, 6,7-dihydro-7-hydroxy-;5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI)
CBNumber:
CB91275916
Molecular Formula:
C7H6N2O2
Molecular Weight:
150.13
MDL Number:
MFCD12924078
MOL File:
115012-09-4.mol
MSDS File:
SDS
Last updated:2026-05-28 04:12:50
Request For Quotation

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) Properties

storage temp. 2-8°C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Crysdot CD11346364 7-Hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one 95+% 115012-09-4 250mg $89 2026-05-27 Buy
Crysdot CD11346364 7-Hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one 95+% 115012-09-4 1g $224 2026-05-27 Buy
AccelPharmtech P2003 6,7-dihydro-7-hydroxy-5H-Pyrrolo[3,4-b]pyridin-5-one 97.00% 115012-09-4 1G $3120 2026-05-21 Buy
AccelPharmtech P2003 6,7-dihydro-7-hydroxy-5H-Pyrrolo[3,4-b]pyridin-5-one 97.00% 115012-09-4 5G $5360 2026-05-21 Buy
AccelPharmtech P2003 6,7-dihydro-7-hydroxy-5H-Pyrrolo[3,4-b]pyridin-5-one 97.00% 115012-09-4 25G $13300 2026-05-21 Buy
Product number Packaging Price Buy
CD11346364 250mg $89 Buy
CD11346364 1g $224 Buy
P2003 1G $3120 Buy
P2003 5G $5360 Buy
P2003 25G $13300 Buy

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) Chemical Properties,Uses,Production

Synthesis

5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione

4664-00-0

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI)

115012-09-4

7H-Pyrrolo[3,4-b]pyridin-7-one,5,6-dihydro-5-hydroxy-(9CI)

115012-10-7

The general procedure for the synthesis of 7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one and compounds (CAS:115012-10-7) from 2,3-pyridinedicarboximide was as follows: 0.74 g (5 mmol) of 2,3-pyridinedicarboximide was dissolved in 50 ml of a solvent mixture of methanol and chloroform at -20 °C ( methanol:chloroform=1:1, V/V). Subsequently, 0.283 g of sodium borohydride was added and the reaction was monitored by TLC until the disappearance of the feedstock spot. Upon completion of the reaction, the pH of the reaction solution was first adjusted to 3 with 3 mol/L hydrochloric acid, and then adjusted to pH 9 with 2 mol/L sodium hydroxide solution. the solvent was removed by concentration under reduced pressure, and the resulting mixture was separated by silica gel column chromatography (eluent: dichloromethane:methanol=15:1, V/V) to give a white solid (a mixture of compound a-1 and compound b-1 in the ratio of about 3:1 ). Finally, the two isomers were isolated by ethanol recrystallization in 45.1% yield of compound a-1.

References

[1] Bulletin of the Chemical Society of Japan, 1987, vol. 60, # 11, p. 4178 - 4180
[2] Patent: CN105541833, 2016, A. Location in patent: Paragraph 0152; 0153; 0154
[3] Bulletin of the Chemical Society of Japan, 1989, vol. 62, # 4, p. 1205 - 1210
[4] European Journal of Medicinal Chemistry, 2012, vol. 55, p. 58 - 66,9

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) Preparation Products And Raw materials

Raw materials

5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione Chloroform Methanol Sodium borohydride

Preparation Products

3-Pyridinecarboxamide,2-(hydroxymethyl)-(9CI)

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
BePharm Ltd 400-685-9117 market@bepharm.com China 15081 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-58859352 19370895928 sales01@aikonchem.com China 15078 58
Shanghai Haohong Scientific Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39718 58
Tangshan Jinyuan Biotechnology Co., Ltd 15222523250 446750422@qq.com China 299 58
Aladdin Scientific tp@aladdinsci.com United States 50089 58
Supplier Advantage
BePharm Ltd 60
Amadis Chemical Company Limited 58
Aikon International Limited 58
Shanghai Haohong Scientific Co., Ltd. 58
Tangshan Jinyuan Biotechnology Co., Ltd 58
Aladdin Scientific 58

115012-09-4(5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI))Related Search:

5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione 6,7-dihydropyrrolo[3,4-b]pyridin-5-one 5H-Pyrrolo[3,4-b]pyridin-5-one, 3-chloro-6,7-dihydro- 3-broMo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one 5H-Pyrrolo[3,4-b]pyridin-5-one, 2-chloro-6,7-dihydro-
3-Hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one

1of2

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) 7-Hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one 6,7-dihydro-7-hydroxy-5H-Pyrrolo[3,4-b]pyridin-5-one 5H-Pyrrolo[3,4-b]pyridin-5-one, 6,7-dihydro-7-hydroxy- 115012-09-4 PYRROLIDINE PYRIDINE