2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER
- CAS No.
- 452972-14-4
- Chemical Name:
- 2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER
- Synonyms
- 2-Fl;2-fluoropyridine-3-borate acid;2-Fluoropyridine-3-boronic 2-FLUOROPYRIDINE-3-BORONIC ACID PICOL ESTER;2-Fluoro-3-pyridylboronic acid pinacol ester;2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER;2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborol;2-Fluoropyridine-3-boronic acid, pinacol ester 95%;2-Fluoropyridine-3-boronic acid pinacol ester ,98%;pyridine, 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborol
- CBNumber:
- CB9130203
- Molecular Formula:
- C11H15BFNO2
- Molecular Weight:
- 223.05
- MDL Number:
- MFCD06798245
- MOL File:
- 452972-14-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37 | |||||||||
| TSCA | No | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29319090 | |||||||||
| NFPA 704 |
|
2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F1105 | 2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine >98.0%(GC)(T) | 452972-14-4 | 1g | $52 | 2025-07-31 | Buy |
| TCI Chemical | F1105 | 2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine >98.0%(GC)(T) | 452972-14-4 | 5g | $153 | 2025-07-31 | Buy |
| TRC | F596213 | 2-Fluoropyridine-3-boronicacid,pinacolester | 452972-14-4 | 250mg | $55 | 2021-12-16 | Buy |
| TRC | F596213 | 2-Fluoropyridine-3-boronicacid,pinacolester | 452972-14-4 | 100mg | $45 | 2021-12-16 | Buy |
| AK Scientific | X1360 | 2-Fluoropyridine-3-boronicacidpinacolester | 452972-14-4 | 10g | $181 | 2021-12-16 | Buy |
2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER Chemical Properties,Uses,Production
Chemical Properties
White to light yellow solid
Uses
2-Fluoropyridine-3-boronic acid, pinacol ester
Synthesis
372-48-5
25015-63-8
452972-14-4
Freshly distilled diisopropylamine (42.5 g, 0.42 mol) was dissolved in ether under nitrogen protection and cooled to 0°C. n-Butyllithium (2.5 M, 175 mL) was slowly added and stirred continuously at 0 °C for 30 min. Subsequently, the reaction system was cooled to -60 °C and an ether solution of 2-fluoropyridine (34.0 g, 0.35 mol) was added slowly dropwise and stirring was continued at -60 °C for 1 hour. An ether solution of triisopropoxyborate (82.4 g, 0.44 mol) was added dropwise, then the mixture was gradually warmed to room temperature and stirred for 2 hours. An ether solution of pinacol (55.6 g, 0.47 mol) was added dropwise over 10 minutes, followed by glacial acetic acid (22.1 g, 0.37 mol). The reaction mixture was stirred overnight at room temperature, filtered and the filtrate was extracted with 5% aqueous sodium hydroxide solution. The pH of the aqueous phase was slowly adjusted to 6-7 with 3N hydrochloric acid, ensuring that the temperature was below 5 °C, and then extracted with ethyl acetate. The organic phases were combined and concentrated in vacuum to remove the solvent to afford the target product 2-fluoropyridine-3-boronic acid pinacol ester (27.0 g, 34% yield).
References
[1] Patent: CN103102349, 2017, B. Location in patent: Paragraph 0171-0173
2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 9028 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
View Lastest Price from 2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-05 | 2-Fluoropyridine-3-boronic acid pinacol ester
452972-14-4
|
US $3.00-9.00 / KG | 0.1KG | 99% | g-kg-tons, free sample is available | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2019-07-11 | 2-Fluoropyridine-3-boronic acid pinacol ester
452972-14-4
|
US $3.00 / KG | 1KG | 99 | 100kg | Career Henan Chemical Co |
-
- 2-Fluoropyridine-3-boronic acid pinacol ester
452972-14-4
- US $3.00-9.00 / KG
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2-Fluoropyridine-3-boronic acid pinacol ester
452972-14-4
- US $3.00 / KG
- 99
- Career Henan Chemical Co
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