lithospermic acid
- CAS No.
- 28831-65-4
- Chemical Name:
- lithospermic acid
- Synonyms
- Aids071478;Aids-071478;Alkaloic acid;Lithospermsaeure;lithospermic acid;Clinopodic acid H;Lithospermic acid-RM;(+)-Lithospermic acid;lithospermic acid, 10 mM in DMSO;4-{(E)-2-[1-Carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl}-2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylic acid
- CBNumber:
- CB91357544
- Molecular Formula:
- C27H22O12
- Molecular Weight:
- 538.46
- MDL Number:
- MFCD03427311
- MOL File:
- 28831-65-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Lithospermic acid phyproof® Reference Substance | PHL80491 | 10 mg | $520 |
| Lithospermic Acid ≥98% | 33694 | 1mg | $81 |
| Lithospermic Acid ≥98% | 33694 | 5mg | $317 |
| Lithospermic Acid ≥98% | 33694 | 10mg | $515 |
| Lithospermic Acid ≥98% | 33694 | 25mg | $789 |
| More product size | |||
| Melting point | 183-188 °C |
|---|---|
| Boiling point | 862.6±65.0 °C(Predicted) |
| Density | 1.642±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Soluble in methan |
| pka | 2.77±0.10(Predicted) |
| form | powder |
| color | White |
| Major Application | food and beverages |
| InChIKey | UJZQBMQZMKFSRV-RGKBJLTCSA-N |
| SMILES | O1C2=C(O)C=CC(/C=C/C(O[C@@H](C(O)=O)CC3=CC=C(O)C(O)=C3)=O)=C2[C@H](C(O)=O)[C@H]1C1=CC=C(O)C(O)=C1 |
| FDA UNII | 100IP83JAC |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
lithospermic acid price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL80491 | Lithospermic acid phyproof® Reference Substance | 28831-65-4 | 10 mg | $520 | 2026-04-30 | Buy |
| Cayman Chemical | 33694 | Lithospermic Acid ≥98% | 28831-65-4 | 1mg | $81 | 2026-04-30 | Buy |
| Cayman Chemical | 33694 | Lithospermic Acid ≥98% | 28831-65-4 | 5mg | $317 | 2026-04-30 | Buy |
| Cayman Chemical | 33694 | Lithospermic Acid ≥98% | 28831-65-4 | 10mg | $515 | 2026-04-30 | Buy |
| Cayman Chemical | 33694 | Lithospermic Acid ≥98% | 28831-65-4 | 25mg | $789 | 2026-04-30 | Buy |
lithospermic acid Chemical Properties,Uses,Production
Chemical Properties
Pale yellow crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of Salvia miltiorrhiza, Lithospermum erythrorhizon of the Boraginaceae family.
Uses
Shikoric acid has the functions of improving kidney function, preventing and treating cardiovascular diseases, and anti-oxidation.
Biological Activity
Lithospermic acid, a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, has antioxidant and hepatoprotective activities against CCl4-induced acute and in vitro liver injury.
in vivo
Lithospermic acid (50 mg/kg, po for 6 days) exhibits cardioprotective efficacy against MI/R injury in mouse models[2].
Lithospermic acid (10-30 mg/kg, po, single dose) exhibits uric acid lowering and anti-inflammatory effects in rats hyperuricemia and gouty arthritis models[3].
| Animal Model: | C57BL/6 mouse MI/R injury models[2] |
| Dosage: | 50 mg/kg |
| Administration: | po for 6 days |
| Result: | Improved MI/R-induced cardiac dysfunction. |
| Animal Model: | Hyperuricemia and gouty arthritis model[3] |
| Dosage: | 10-30 mg/kg |
| Administration: | po, single dose |
| Result: | Reduced the serum uric acid and monosodium urate crystal-induced paw edema. |
target
ROS | ERK | MMP(e.g.TIMP) | DNA/RNA Synthesis | Caspase | TNF-α | HIV | SOD | GPx | Xanthine oxidas | MPO | MDA
lithospermic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 954 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from lithospermic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | lithospermic acid
28831-65-4
|
US $33.00-97.00 / mg | 99.25% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | Lithospermic acid
28831-65-4
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2021-07-13 | lithospermic acid
28831-65-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- lithospermic acid
28831-65-4
- US $33.00-97.00 / mg
- 99.25%
- TargetMol Chemicals Inc.
-
- Lithospermic acid
28831-65-4
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- lithospermic acid
28831-65-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
