ChemicalBook >> CAS DataBase List >>8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

CAS No.
28936-94-9
Chemical Name:
8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione
Synonyms
8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(benzyl)-1,3,8-triazaspiro[4.5]decane-2,4-quinone;8-(phenylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(Phenylmethyl)-1,3,8-triazaspiro(4.5)decane-2,4-dione;1,3,8-Triazaspiro(4.5)decane-2,4-dione, 8-(phenylmethyl)-
CBNumber:
CB9137202
Molecular Formula:
C14H17N3O2
Molecular Weight:
259.3
MDL Number:
MFCD00793797
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-09-12 18:55:56

8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione Properties

Melting point 259-261 °C
Density 1.29±0.1 g/cm3(Predicted)
refractive index 1.628
storage temp. Sealed in dry,Room Temperature
pka 10.07±0.20(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C14H17N3O2/c18-12-14(16-13(19)15-12)6-8-17(9-7-14)10-11-4-2-1-3-5-11/h1-5H,6-10H2,(H2,15,16,18,19)
InChIKey ISFXLJGTXHSNDU-UHFFFAOYSA-N
SMILES N1C2(CCN(CC3=CC=CC=C3)CC2)C(=O)NC1=O
EWG's Food Scores 1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech AR2633 8-BENZYL-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONE 95% 28936-94-9 1G $69 2026-04-30 Buy
AstaTech AR2633 8-BENZYL-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONE 95% 28936-94-9 5G $207 2026-04-30 Buy
AstaTech AR2633 8-BENZYL-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONE 95% 28936-94-9 25G $620 2026-04-30 Buy
Synthonix B57730 8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione 95% 28936-94-9 1g $141 2026-05-06 Buy
Synthonix B57730 8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione 95% 28936-94-9 5g $160 2026-05-06 Buy
Product number Packaging Price Buy
AR2633 1G $69 Buy
AR2633 5G $207 Buy
AR2633 25G $620 Buy
B57730 1g $141 Buy
B57730 5g $160 Buy

8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione Chemical Properties, Uses, Production

Description

8-benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione is a pharmaceutical intermediate compound that can be used to prepare biologically active compounds. Studies have shown that 1,3, 8-triazo [4.5] decane-2, 4-dione is a novel chemical type of agonist with DOR selectivity. δ -opioid receptors (DOR) are potential targets for the treatment of neurological and mental disorders. These agonists are similar to 1,3, 8-triazo [4.5] decane-4-one analogues and have been reported to be weakly selective NOR agonists with moderate binding affinity for DOR, MOR and KOR.

Uses

8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione is a useful research reagent used in the synthesis of spirohydantoins from basic heterocyclic ketones.

Toxicology

mouse: LD > 800 mg/kg (oral)

8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 76)
Supplier Tel Email Country ProdList Advantage
Shanghai Jinsheng Pharmaceutical Co., Ltd. 1365-13651960330 13651960330 xiangfeixia@jspharmatech.com China 401 58
Shanghai civi chemical technology co.,Ltd 86-21-34053660 sale@labgogo.com China 9853 52
AstaTech (Chengdu) Pharma. Co., Ltd. 15928766785 15928766785 wupengcheng@astatech.cn China 1997 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Chengdu Firster Pharmaceutical Co., Ltd. 028-87078428 028-87074958 chengzhenyong@cdfirster.com China 2580 60
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4777 55
Accela ChemBio Inc. +1(858) 699-3322 marketing@accelachem.com United States 6022 65
SPIRO PHARMA eric_feng1954@126.com China 9239 55
Nanjing River Chemical Co., Ltd. 13951936332 18305166317 info@serpharm.com China 493 55
Qingdao IniKem BioPharmaTech Co.,Ltd 0532-58268781 18561687109 sales@inikem.com China 299 55

8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione Spectrum

1,3,8-Triazaspiro(4.5)decane-2,4-dione, 8-(phenylmethyl)- 8-(benzyl)-1,3,8-triazaspiro[4.5]decane-2,4-quinone 8-(Phenylmethyl)-1,3,8-triazaspiro(4.5)decane-2,4-dione 8-(phenylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione 8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione 28936-94-9 C14H17N3O2