3-((4-bromo-3-fluorophenyl)amino)piperidine-2,6-dione

CAS No.
2962967-27-5
Chemical Name:
3-((4-bromo-3-fluorophenyl)amino)piperidine-2,6-dione
Synonyms
3-((4-bromo-3-fluorophenyl)amino)piperidine-2,6-dione;2,6-Piperidinedione, 3-[(4-bromo-3-fluorophenyl)amino]-
CBNumber:
CB914211264
Molecular Formula:
C11H10BrFN2O2
Molecular Weight:
301.11
MDL Number:
MOL File:
2962967-27-5.mol
Last updated:2025-05-19 13:47:26

3-((4-bromo-3-fluorophenyl)amino)piperidine-2,6-dione Properties

Boiling point 485.814±45.00 °C(Press: 760.00 Torr)(predicted)
Density 1.665±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 10.951±0.40(predicted)

3-((4-bromo-3-fluorophenyl)amino)piperidine-2,6-dione Chemical Properties,Uses,Production

Uses

CRBN ligand-11 is the E3 ubiquitin ligase ligand for CFT8634 (HY-145925B). CRBN ligand-11 can be used for the synthesis of PROTACs[1][2].

IC 50

Cereblon

References

[1] Zhang xue, et al. Nitrogen-containing heteroaromatic ring compound as well as composition and pharmaceutical use thereof. Patent, WO2023143370, 2023-08-03.
[2] Nasveschuk CG, et, al. Compounds for targeted degradation of brd9. Patent, WO2021178920A1, 2021-09-10.

3-((4-bromo-3-fluorophenyl)amino)piperidine-2,6-dione Preparation Products And Raw materials

Raw materials

Preparation Products

3-((4-bromo-3-fluorophenyl)amino)piperidine-2,6-dione Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Yuxiang Medical Technology Co., Ltd. 13971275651 sales@whyxpharma.com China 1943 58
3-((4-bromo-3-fluorophenyl)amino)piperidine-2,6-dione 2,6-Piperidinedione, 3-[(4-bromo-3-fluorophenyl)amino]- 2962967-27-5