Platelet Activating Factor-16
- CAS No.
- 74389-68-7
- Chemical Name:
- Platelet Activating Factor-16
- Synonyms
- PAF;C16PAF;ACGEPC;PAF (C16);C16-02:0 PC;PAF (C16),99%;C16-PAF-acether;C16-PAF(PAF (C16));C16 ENANTIOMERIC PAF;Rabbit Anti-PAF antibody
- CBNumber:
- CB9143348
- Molecular Formula:
- C26H54NO7P
- Molecular Weight:
- 523.68
- MDL Number:
- MFCD00043214
- MOL File:
- 74389-68-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 247 °C |
|---|---|
| storage temp. | -20°C |
| solubility | Soluble in H2O or ethanol |
| form | lyophilized powder |
| color | White to off-white |
| Water Solubility | Soluble to 100 mM in water |
| BRN | 3574588 |
| InChI | 1S/C26H54NO7P.H2O/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5;/h26H,6-24H2,1-5H3;1H2/t26-;/m1./s1 |
| InChIKey | HFMSDOHEENWULV-UFTMZEDQSA-N |
| SMILES | O.CCCCCCCCCCCCCCCCOC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(C)=O |
| FDA UNII | 42EWD89I80 |
| UNSPSC Code | 12352211 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| Hazard Codes | Xn |
| Risk Statements | 22-38-40-48/20/22 |
| Safety Statements | 36/37-24/25-22 |
| RIDADR | UN 1888 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | EC6060000 |
| F | 10-21 |
| Storage Class | 11 - Combustible Solids |
Platelet Activating Factor-16 price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 511075 | Platelet Activating Factor-16 | 74389-68-7 | 1mg | $60.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 511075 | Platelet Activating Factor-16 | 74389-68-7 | 5mg | $139 | 2026-04-30 | Buy |
| Cayman Chemical | 60900 | PAF C-16 ≥98% | 74389-68-7 | 1mg | $58 | 2026-04-30 | Buy |
| Cayman Chemical | 60900 | PAF C-16 ≥98% | 74389-68-7 | 5mg | $131 | 2026-04-30 | Buy |
| Cayman Chemical | 60900 | PAF C-16 ≥98% | 74389-68-7 | 10mg | $232 | 2026-04-30 | Buy |
Platelet Activating Factor-16 Chemical Properties, Uses, Production
Uses
PAF (C16) (cas# 74389-68-7) is a blood platelet-activating factor, used to study human airway smooth muscle cell line.
Uses
C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. It may also be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.
Definition
ChEBI: A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.
General Description
C16-02:0 PC, also known as 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16 PAF) (acetyl PAF), is a platelet-activating factor (PAF). Acetyl PAF is present in the body and it contains ether-linked hexadecyl chain at the sn-1 position and an acetyl group at the sn-2 position.
Biological Activity
Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.
Biochem/physiol Actions
Platelet-activating factor (PAF) is a pro-inflammatory agent that exhibits variety of biological and pharmacological effects. It plays a major role in initiation and progression of atherosclerosis. PAF acts as a potential biomarker for coronary artery diseases. It yields LysoPAF (1-O-alkyl-2-hydroxy-sn-glycero-3-phosphocholine) on hydrolysis by platelet-activating factor-acetylhydrolase.
storage
Store at -20°C
Platelet Activating Factor-16 Preparation Products And Raw materials
Raw materials
Preparation Products
Platelet Activating Factor-16 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
