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5-BROMO-2-METHOXY-3-CYANOPYRIDINE

5-BROMO-2-METHOXY-3-CYANOPYRIDINE structure

CAS No.: 884495-39-0

Chemical Name:: 5-BROMO-2-METHOXY-3-CYANOPYRIDINE

Synonyms: 5-Bromo-2-methoxypyridin-3-amine;5-BroMo-2-Methoxy-3-aMino...;5-bromo-6-methoxypyridin-4-amine;2-methoxy-3-amino-5-bromopyridine;5-BROMO-2-METHOXY-3-AMINOPYRIDINE;5-BROMO-2-METHOXY-3-CYANOPYRIDINE;3-PyridinaMine,5-broMo-2-Methoxy-;5-BroMo-2-(Methyloxy)-3-pyridinaMine;3-Amino-5-bromo-2-methoxypyridine,96%;3-Amino-5-bromo-2-methoxypyridine 98%

CBNumber:: CB91471022

Molecular Formula:: C6H7BrN2O

Molecular Weight:: 203.04

MDL Number:: MFCD07368887

MOL File:: 884495-39-0.mol

MSDS File:: SDS

Last updated:2026-05-28 04:47:43

Product description	Number	Pack Size	Price
5-Bromo-2-methoxypyridin-3-amine Aldrich	ADE000451	1g	$463
3-Amino-5-bromo-2-methoxypyridine >97%	OR42139	5g	$21
3-Amino-5-bromo-2-methoxypyridine >97%	OR42139	25g	$36
3-Amino-5-bromo-2-methoxypyridine 98%	AS31641	5g	$23
3-Amino-5-bromo-2-methoxypyridine >97%	OR42139	100g	$139
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5-BROMO-2-METHOXY-3-CYANOPYRIDINE Properties

Melting point	53-55℃
Boiling point	284.5±35.0 °C(Predicted)
Density	1.622±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	1.98±0.20(Predicted)
Appearance	Off-white to light brown Solid
Water Solubility	Slightly soluble in water.
InChI	InChI=1S/C6H7BrN2O/c1-10-6-5(8)2-4(7)3-9-6/h2-3H,8H2,1H3
InChIKey	HJOOFLFWIISCAI-UHFFFAOYSA-N
SMILES	C1(OC)=NC=C(Br)C=C1N

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H315-H317-H318-H335

Precautionary statements

P280-P301+P312+P330-P302+P352-P305+P351+P338+P310

Hazard Codes

Risk Statements

22-37/38-41-43

Safety Statements

26-36/37/39

WGK Germany

HazardClass

IRRITANT

HS Code

2933399990

NFPA 704

	0
2		0

5-BROMO-2-METHOXY-3-CYANOPYRIDINE price More Price(72)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	ADE000451	5-Bromo-2-methoxypyridin-3-amine Aldrich	884495-39-0	1g	$463	2023-06-20	Buy
Apolloscientific	OR42139	3-Amino-5-bromo-2-methoxypyridine >97%	884495-39-0	5g	$21	2026-06-04	Buy
Apolloscientific	OR42139	3-Amino-5-bromo-2-methoxypyridine >97%	884495-39-0	25g	$36	2026-06-04	Buy
Activate Scientific	AS31641	3-Amino-5-bromo-2-methoxypyridine 98%	884495-39-0	5g	$23	2026-06-04	Buy
Apolloscientific	OR42139	3-Amino-5-bromo-2-methoxypyridine >97%	884495-39-0	100g	$139	2026-06-04	Buy

Product number	Packaging	Price	Buy
ADE000451	1g	$463	Buy
OR42139	5g	$21	Buy
OR42139	25g	$36	Buy
AS31641	5g	$23	Buy
OR42139	100g	$139	Buy

5-BROMO-2-METHOXY-3-CYANOPYRIDINE Chemical Properties,Uses,Production

Uses

3-Amino-5-bromo-2-methoxypyridine is used as pharmaceutical intermediate.

Synthesis

152684-30-5

884495-39-0

General procedure for the synthesis of 3-amino-5-bromo-2-methoxypyridine from 5-bromo-2-methoxy-3-nitropyridine: To a solution of 5-bromo-2-methoxy-3-nitropyridine (19.0 g, 82 mmol) in ethyl acetate (300 mL) was added tin (II) chloride dihydrate (74 g, 328 mmol). The reaction mixture was stirred and refluxed for 3 hours (note: an exothermic phenomenon occurs at the beginning of the reaction, which gradually subsides after about 10 minutes, at which time the heating bath can be temporarily removed). After completion of the reaction, the reaction mixture was cooled to room temperature and concentrated under reduced pressure to a light yellow slurry. The slurry was poured into water (300 mL), 6 N sodium hydroxide solution (300 mL), ice (300 g), and dichloromethane (300 mL) were added, and stirred for 2 hours until most of the solids were dissolved. A small amount of insoluble material was removed by filtration, the organic phase was separated, dried over anhydrous sodium sulfate, filtered and evaporated to dryness. The residual brown oil was solidified by grinding with hexane, filtered and dried under vacuum to give the target product 3-amino-5-bromo-2-methoxypyridine (13.40 g, 81% yield) as a light green solid. Mass spectrum (electrospray ionization) m/e: 202.8 [M+H]+.

References

[1] Patent: US2014/134133, 2014, A1. Location in patent: Paragraph 0387
[2] Patent: WO2008/33854, 2008, A1. Location in patent: Page/Page column 74-75
[3] Patent: WO2014/22128, 2014, A1. Location in patent: Paragraph 0150
[4] Patent: US2014/234254, 2014, A1. Location in patent: Paragraph 0300; 0301; 0302
[5] Patent: CN103539777, 2016, B. Location in patent: Paragraph 0304; 0305

5-BROMO-2-METHOXY-3-CYANOPYRIDINE Preparation Products And Raw materials

Raw materials

5-BROMO-2-METHOXY-3-NITRO-PYRIDINE Water Ethyl acetate Dichloromethane Stannous chloride

Sodium hydroxide

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Preparation Products

2,4-difluoro-N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)benzenesulfonamide N-(5-bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide N-(5-broMo-2-Methoxypyridin-3-yl)-1-ethyl-1H-pyrazole-4-sulfonaMide

5-BROMO-2-METHOXY-3-CYANOPYRIDINE Suppliers

Global( 209)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
HaBo Hong Kong Co., Limited.	+86-25-18512596065	info@habotech.com	CHINA	933	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
HaBo Hong Kong Co., Limited.	58
Accela ChemBio Inc.	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
Antai Fine Chemical Technology Co.,Limited	58

View Lastest Price from 5-BROMO-2-METHOXY-3-CYANOPYRIDINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	5-BROMO-2-METHOXY-3-CYANOPYRIDINE 884495-39-0	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2020-05-13	5-Bromo-2-methoxypyridin-3-amine 884495-39-0		1KG	99.0%	500 MT	Shaanxi Dideu Medichem Co. Ltd
2019-07-06	5-BROMO-2-METHOXY-3-CYANOPYRIDINE 884495-39-0	$1.00	1kg	98%	200kg	Career Henan Chemical Co

5-BROMO-2-METHOXY-3-CYANOPYRIDINE
884495-39-0
$1.10
99.00%
Dideu Industries Group Limited

5-Bromo-2-methoxypyridin-3-amine
884495-39-0
99.0%
Shaanxi Dideu Medichem Co. Ltd

5-BROMO-2-METHOXY-3-CYANOPYRIDINE
884495-39-0
$1.00
98%
Career Henan Chemical Co

5-BROMO-2-METHOXY-3-CYANOPYRIDINE Spectrum

5-BROMO-2-METHOXY-3-CYANOPYRIDINE(884495-39-0)¹HNMR

884495-39-0(5-BROMO-2-METHOXY-3-CYANOPYRIDINE)Related Search:

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5-BROMO-2-METHOXY-3-CYANOPYRIDINE 5-BROMO-2-METHOXY-3-AMINOPYRIDINE 5-BroMo-2-Methoxy-3-aMino... 3-PyridinaMine,5-broMo-2-Methoxy- 5-BroMo-2-(Methyloxy)-3-pyridinaMine 5-Bromo-2-methoxypyridin-3-amine, 3-Amino-5-bromopyridin-2-yl methyl ether 3-Amino-5-bromopyridin-2-yl methyl ether 2-methoxy-3-amino-5-bromopyridine 3-Amino-5-bromo-2-methoxypyridine 98% 3-Amino-5-bromo-2-methoxypyridine,96% 5-bromo-6-methoxypyridin-4-amine 5-BROMO-2-METHOXY-3-CYANOPYRIDINE ISO 9001：2015 REACH 5-Bromo-2-methoxypyridin-3-amine 884495-39-0 Heterocycle-Pyridine series Pyridine