5-Bromo-2-fluoropyridine-3-carboxaldehyde
- CAS No.
- 875781-15-0
- Chemical Name:
- 5-Bromo-2-fluoropyridine-3-carboxaldehyde
- Synonyms
- 5-bromo-2-fluoronicotinaldehyde;5-Bromo-2-fluoro-3-formylpyridine;5-Bromo-2-fluoro-pyridin-3-carbaldehyde;5-Bromo-2-fluoropyridine-3-carboxaldehyde;5-Bromo-2-fluoro-3-pyridinecarboxaldehyde;3-Pyridinecarboxaldehyde, 5-broMo-2-fluoro-;5-Bromo-2-fluoropyridine-3-carboxaldehyde ISO 9001：2015 REACH;5-Bromo-2-fluoropyridine-3-carboxaldehyde, 5-Bromo-2-fluoro-3-formylpyridine
- CBNumber:
- CB91471279
- Molecular Formula:
- C6H3BrFNO
- Molecular Weight:
- 204
- MDL Number:
- MFCD09842440
- MOL File:
- 875781-15-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-2-fluoronicotinaldehyde ≥95% | PC11103 | 1g | $21 |
| 5-Bromo-2-fluoronicotinaldehyde ≥95% | PC11103 | 5g | $55 |
| 5-Bromo-2-fluoro-3-pyridinecarboxaldehyde 98% | AS30909 | 5g | $31 |
| 5-Bromo-2-fluoro-3-pyridinecarboxaldehyde 98% | AS30909 | 25g | $99 |
| 5-Bromo-2-fluoro-3-pyridinecarboxaldehyde 98% | AS30909 | 100g | $294 |
| More product size | |||
| Boiling point | 258.2±35.0 °C(Predicted) |
|---|---|
| Density | 1.778±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -4.59±0.20(Predicted) |
| form | Powder |
| color | Off-white to pale yellow |
| InChI | InChI=1S/C6H3BrFNO/c7-5-1-4(3-10)6(8)9-2-5/h1-3H |
| InChIKey | MUYVOGAJRCBWCY-UHFFFAOYSA-N |
| SMILES | C1(F)=NC=C(Br)C=C1C=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Safety Statements | 24/25 | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
5-Bromo-2-fluoropyridine-3-carboxaldehyde price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC11103 | 5-Bromo-2-fluoronicotinaldehyde ≥95% | 875781-15-0 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC11103 | 5-Bromo-2-fluoronicotinaldehyde ≥95% | 875781-15-0 | 5g | $55 | 2026-06-04 | Buy |
| Activate Scientific | AS30909 | 5-Bromo-2-fluoro-3-pyridinecarboxaldehyde 98% | 875781-15-0 | 5g | $31 | 2026-06-04 | Buy |
| Activate Scientific | AS30909 | 5-Bromo-2-fluoro-3-pyridinecarboxaldehyde 98% | 875781-15-0 | 25g | $99 | 2026-06-04 | Buy |
| Activate Scientific | AS30909 | 5-Bromo-2-fluoro-3-pyridinecarboxaldehyde 98% | 875781-15-0 | 100g | $294 | 2026-06-04 | Buy |
5-Bromo-2-fluoropyridine-3-carboxaldehyde Chemical Properties,Uses,Production
Uses
5-Bromo-2-fluoro-3-pyridinecarboxaldehyde is used in the synthesis of [2,3-d]pyrimidine derivatives useful as Raf kinase inhibitors. Also used in the preparation of XIa inhibitors.
Synthesis
2591-86-8
766-11-0
875781-15-0
The general procedure for the synthesis of 5-bromo-2-fluoro-3-formylpyridine using N-formylpiperidine and 2-fluoro-5-bromopyridine as starting materials was as follows: the intermediate 5-bromo-1H-pyrazolo[3,4-b]pyridine was first prepared; subsequently, the crude product was ground in hexane (replacing the operation of crystallization from cyclohexane) according to the method described in WO2006015124 to obtain the target compound 5-bromo-2-fluoro-3-formylpyridine, the product was an off-white solid in 68% yield. Mass spectrometry (electrospray positive ion mode) showed m/z of 203.8 and 205.7 [M+H]+.
References
[1] Patent: US2008/293706, 2008, A1. Location in patent: Page/Page column 27; 85
[2] Patent: US2008/261921, 2008, A1. Location in patent: Page/Page column 73-74
5-Bromo-2-fluoropyridine-3-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Springchem New Material Technology Co.,Limited | +86-021-62885108 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1444 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8827 | 58 |
View Lastest Price from 5-Bromo-2-fluoropyridine-3-carboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 5-Bromo-2-fluoropyridine-3-carboxaldehyde
875781-15-0
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2021-10-16 | 5-Bromo-2-fluoropyridine-3-carboxaldehyde
875781-15-0
|
$10.00 | 1KG | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd | |
 |
2020-05-13 | 5-Bromo-2-fluoropyridine-3-carboxaldehyde
875781-15-0
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
-
- 5-Bromo-2-fluoropyridine-3-carboxaldehyde
875781-15-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5-Bromo-2-fluoropyridine-3-carboxaldehyde
875781-15-0
- $10.00
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
-
- 5-Bromo-2-fluoropyridine-3-carboxaldehyde
875781-15-0
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
