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ChemicalBook >> CAS DataBase List >>1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Structure
1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride structure
CAS No.
2031-23-4
Chemical Name:
1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride
Synonyms
N-CHLOROPROPYL-N-METHYLPIPERAZINE;1-(3-CHLOROPROPYL)-4-METHYLPIPERAZINE HCL;1-(3-Chloropropyl)-4-methylpiperazine DiHCl;N-(3-Chloropropyl)-N'-methylpiperazine2hydrochloride;1-Methyl-4-(3-chloropropyl)piperazine dihydrochloride;1-(3-CHLORO-PROPYL)-4-METHYL-PIPERAZINE, HYDROCHLORIDE;1-(3-CHLOROPROPYL)-4-METHYL PIPERAZINE DIHYDROCHLORIDE;N-(3-CHLOROPROPYL)-N'-METHYL PIPERAZINE DIHYDROCHLORIDE;1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride ,98%;1-(3-chloropropyl)-4-methyl-Piperazine hydrochloride (1:2)
CBNumber:
CB9156281
Molecular Formula:
C8H19Cl3N2
Molecular Weight:
249.61
MDL Number:
MFCD00023304
MOL File:
2031-23-4.mol
MSDS File:
SDS
Last updated:2026-01-13 11:26:47
Product description Number Pack Size Price
1-(3-Chloropropyl)-4-methylpiperazineDihydrochloride C379745 25g $150
1-(3-CHLOROPROPYL)-4-METHYLPIPERAZINE DIHYDROCHLORIDE 95.00% HCH0015067 1G $162.75
1-(3-Chloropropyl)-4-methylpiperazinedihydrochloride OR14748 5g $190
1-(3-Chloropropyl)-4-methylpiperazinedihydrochloride OR14748 1g $48
1-(3-Chloropropyl)-4-methylpiperazinedihydrochloride 3H32-5-P0 1g $53
More product size
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1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Properties

Melting point 255-257 °C (decomp)(Solv: ethanol (64-17-5))
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO, Methanol
form Solid
color White
InChI 1S/C8H17ClN2.2ClH/c1-10-5-7-11(8-6-10)4-2-3-9;;/h2-8H2,1H3;2*1H
InChIKey RRZYWKLLIIIINP-UHFFFAOYSA-N
SMILES Cl.Cl.CN1CCN(CCCCl)CC1
CAS DataBase Reference 2031-23-4(CAS DataBase Reference)
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
WGK Germany  WGK 3
HS Code  2933599590
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C379745 1-(3-Chloropropyl)-4-methylpiperazineDihydrochloride 2031-23-4 25g $150 2021-12-16 Buy
American Custom Chemicals Corporation HCH0015067 1-(3-CHLOROPROPYL)-4-METHYLPIPERAZINE DIHYDROCHLORIDE 95.00% 2031-23-4 1G $162.75 2021-12-16 Buy
Apolloscientific OR14748 1-(3-Chloropropyl)-4-methylpiperazinedihydrochloride 2031-23-4 5g $190 2021-12-16 Buy
Apolloscientific OR14748 1-(3-Chloropropyl)-4-methylpiperazinedihydrochloride 2031-23-4 1g $48 2021-12-16 Buy
SynQuest Laboratories 3H32-5-P0 1-(3-Chloropropyl)-4-methylpiperazinedihydrochloride 2031-23-4 1g $53 2021-12-16 Buy
Product number Packaging Price Buy
C379745 25g $150 Buy
HCH0015067 1G $162.75 Buy
OR14748 5g $190 Buy
OR14748 1g $48 Buy
3H32-5-P0 1g $53 Buy

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Chemical Properties,Uses,Production

Uses

1-(3-Chloropropyl)-4-methylpiperazine Dihydrochloride

Synthesis

1-Methylpiperazine

109-01-3

1-Bromo-3-chloropropane

109-70-6

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride

2031-23-4

N-methylpiperazine (30 mmol, 3.3 mL), 4 mL of 25% NaOH solution, and 40 mL of acetone were added to a 100 mL round-bottomed flask under ice bath cooling conditions. Subsequently, 1-bromo-3-chloropropane (30 mmol, 3 mL) was added and stirred in an ice bath until the reaction was complete, ensuring that all insoluble material was completely dissolved. The reaction mixture was allowed to stand at room temperature for 24 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. 20 mL of water was added to the residue, which was subsequently extracted with dichloromethane. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give a clarified oil. The reaction flask was placed in an ice bath and 50 mL of ethyl acetate was added. 2.5 mL of concentrated hydrochloric acid was added slowly and dropwise until a large amount of white solid was observed to be produced. During this process, the pH of the reaction system needed to be controlled to be about 2. The solvent was again removed by distillation under reduced pressure and the resulting solid was recrystallized with 100 mL of anhydrous ethanol. Finally, after filtration and drying, 3.3 g of white solid product was obtained as 1-(3-chloropropyl)-4-methylpiperazine dihydrochloride.

References

[1] Patent: CN105884699, 2016, A. Location in patent: Paragraph 0044; 0045
[2] Patent: WO2011/73092, 2011, A1. Location in patent: Page/Page column 29; 30

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Preparation Products And Raw materials

Raw materials

1-Methylpiperazine 1-Bromo-3-chloropropane Sodium hydroxide Acetone

Preparation Products

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Suppliers

Global( 144)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21592 55
Chembon Pharmaceutical Co., Ltd. 		+86-28-8425-2981 CHINA 722 55
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10404 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 18895 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15079 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Chembon Pharmaceutical Co., Ltd. 		55
Shenzhen Nexconn Pharmatechs Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Dideu Industries Group Limited 		58
AFINE CHEMICALS LIMITED 		58

View Lastest Price from 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride pictures 2025-11-18 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride
2031-23-4
 US $1.10 / g 1g 99.0% Min 100 Tons Dideu Industries Group Limited
1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride pictures 2025-09-25 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride
2031-23-4
 US $32.00-1.40 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride pictures 2025-04-04 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride
2031-23-4
 US $0.00-0.00 / KG 1KG 98% 1tone Henan Aochuang Chemical Co.,Ltd.

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Spectrum

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride(2031-23-4)1HNMR

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Piperazine, 1-(3-chloropropyl)-4-methyl-, hydrochloride (1:2) 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride ,98% 1-Methyl-4-(3-chloropropyl)piperazine dihydrochloride 1-(3-Chloropropyl)-4-methylpiperazine DiHCl 1-(3-CHLOROPROPYL)-4-METHYL PIPERAZINE DIHYDROCHLORIDE 1-(3-CHLOROPROPYL)-4-METHYLPIPERAZINE HCL 1-(3-CHLORO-PROPYL)-4-METHYL-PIPERAZINE, HYDROCHLORIDE N-(3-Chloropropyl)-N'-methylpiperazine2hydrochloride N-CHLOROPROPYL-N-METHYLPIPERAZINE N-(3-CHLOROPROPYL)-N'-METHYL PIPERAZINE DIHYDROCHLORIDE 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride ISO 9001：2015 REACH 1-(3-chloropropyl)-4-methyl-Piperazine hydrochloride (1:2) 2031-23-4 C8H17ClN22HCl C8H19Cl3N2 C8H17ClN22ClH C8H17ClN22HCI