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Coelenterazine

CAS No.
55779-48-1
Chemical Name:
Coelenterazine
Synonyms
Coelenteramine;CLZ-N;CLZN-N;CS-2297;Nanofuel;enterazine;Preluciferin;Coelenterazin;COELENTERAZINE;COELENTERAZIN N
CBNumber:
CB9162998
Molecular Formula:
C26H21N3O3
Molecular Weight:
423.46
MDL Number:
MFCD00467176
MOL File:
55779-48-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08

Coelenterazine Properties

Melting point 176–181 ℃ (decompose)
Boiling point 641.4±65.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility methanol and ethanol: soluble
pka 9.91±0.15(Predicted)
form solid
color yellow
Sensitive Moisture & Light Sensitive
λmax 429nm
Biological Applications Calciumindicator; detecting luciferase,protease,gene expression,nucleic acids,proteins,stem cells,quantum dot conjugates,superoxide; tracing protein dynamics; as a substrate for luciferase,alka
InChI InChI=1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2
InChIKey YHIPILPTUVMWQT-UHFFFAOYSA-N
SMILES C12N=C(CC3=CC=C(O)C=C3)C(=O)N1C=C(C1=CC=C(O)C=C1)NC=2CC1=CC=CC=C1
CAS DataBase Reference 55779-48-1(CAS DataBase Reference)
FDA UNII 3O1CB88RRD
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H413
Precautionary statements  P273-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  3
10
HS Code  29339900
Storage Class 11 - Combustible Solids
NFPA 704
0
2 0

Coelenterazine price More Price(82)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 233900 Coelenterazine - CAS 122384-88-7 - Calbiochem A cell-permeable aequorin luminophore that acts as a very sensitive and specific chemiluminescence probe of the superoxide anion. 55779-48-1 250μg $370 2026-04-30 Buy
Sigma-Aldrich C2230 Coelenterazine, native solid 55779-48-1 50μg $186 2023-06-20 Buy
Cayman Chemical 16123 Coelenterazine ≥85% 55779-48-1 500μg $72 2026-04-30 Buy
Cayman Chemical 16123 Coelenterazine ≥85% 55779-48-1 1mg $115 2026-04-30 Buy
Cayman Chemical 16123 Coelenterazine ≥85% 55779-48-1 5mg $501 2026-04-30 Buy
Product number Packaging Price Buy
233900 250μg $370 Buy
C2230 50μg $186 Buy
16123 500μg $72 Buy
16123 1mg $115 Buy
16123 5mg $501 Buy

Coelenterazine Chemical Properties, Uses, Production

Chemical Properties

Yellow Solid

Uses

Coelenterazine, native was used:-

  • For Aequorin assays
  • For measuring the intracellular calcium concentration in response to ionomycin or PMA using aequorin in COS-7 cells
  • In Bioluminescence imaging for analysing the presence of virus-dependent luciferase activity

Uses

Coelenterazine is a luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465nm when Ca2+ binds to the complex. Used to measure Ca2+ concentration in cells with high sensitivity an dlarge dynamic range.

Definition

ChEBI: An imidazopyrazine that is imidazo[1,2-a]pyrazin-3(7H)-one in which positions 2, 6, and 8 are substituted by 4-hydroxybenzyl, 4-hydroxyphenyl, and benzyl groups, respectively.

General Description

Coelenterazine is a luciferin molecule, which is utilized by several luciferases, such as Renilla,Oplophorus andPeriphylla.

Biochem/physiol Actions

Luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465 nm when Ca2+ binds to the complex; used to measure Ca2+ concentration in cells with high sensitivity and large dynamic range.

Coelenterazine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 255)
Supplier Tel Email Country ProdList Advantage
Taizhou Chemedir Biopharm-tech. Co., Ltd 0523-86200218 18994667082 sale1_cmd@chemedir.com China 58 64
Chengdu Celes Technology Co., Ltd 19982073091 2538834896@qq.com China 78 58
Shanghai Qianhao Biotechnology Co., LTD 13524877553 13524877553@163.com China 122 58
Changzhou Chenhong Biotechnology Co., Ltd. +86-0519-85788828 +86-13775037613 sales@chemrenpharm.com China 4058 58
Hefei Leo Biotechnology Co., Ltd 15715515222 leo@leo-sw.com China 132 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50

View Latest Price from Coelenterazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Coelenterazine pictures 2026-07-16 Coelenterazine
55779-48-1
$90.00-319.00 98.08% 10g TargetMol Chemicals Inc.
Coelenterazine pictures 2021-12-18 Coelenterazine
55779-48-1
$10.00 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd
Coelenterazine pictures 2020-02-14 Coelenterazine
55779-48-1
$7.00 1KG 99% 100kg Career Henan Chemical Co

Coelenterazine Spectrum

8-BENZYL-2-(4-HYDROXYBENZYL)-6-(4-HYDROXYPHENYL)IMIDAZO[1,2-A]PYRAZIN-3(7H)-ONE 2-[(4-HYDROXYPHENYL)METHYL]-6-(4-HYDROXYPHENYL)-8-(PHENYLMETHYL)-IMDAZO[1,2-A]PYRAZIN-3-(7H)-ONE Coelenteramine 2-[(4-Hydroxyphenyl)methyl]-6-(4-hydroxyphenyl)-8-(phenylmethyl)-imdazo[1,2-a]pyrazin-3-(7H)-one Imidazo[1,2-a]pyrazin-3(7H)-one,6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)- Oplophorus luciferin
2-(p-Hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzyl-imidazo[1,2-a]pyrazin-3-(7 H)-one
Coelenterazin Luciferin (oplophorus) Nanofuel Preluciferin Preluciferin (watasenia) Watasenia Preluciferin Coelenterazine *CAS#: 55779-48-1* CS-2297 (4aS,4bR,8S,10aR,10bS,12aS)-1,1,10a,12a-tetramethyl-8-(1-methyl-1-pyrrolidin-1-iumyl)-3,4,4a,4b,5,7,8,9,10,10b,11,12-dodecahydro-2H-naphtho[2,1-f]quinolin-1-ium diiodide 2-[(4-HYDROXYPHENYL)METHYL]-6-(4-HYDROXYPHENYL)-8-(PHENYLMETHYL)-IMIDAZO [1,2-A] PYRAZIN-3-(7H)-ONE Coelenterazine luiferin 3,2-DIHYDRO-2-(P-HYDROXYBENZYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZOLO[1,2-A]PYRAZIN-3-ONE 2-(P-HYDROXYBENZYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZIN-3-(7H)-ONE 2-(P-HYDROXYBENZYL)-6-(P-HYDROXYPHENYL)-8-BENZYL-IMIDAZOL[1,2-A]PYRAZIN-3-(7H)-ONE 2-(BETA-NAPHTHYLMETHYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZIN-3-(7H)-ONE 2-(BETA-NAPHTHYLMETHYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZINE-3-(7H)-ONE COELENTERAZIN N Coelenteramine COELENTERAZINE COELENTERAZINE N COELENTERAZINE, NATIVE COELENTERAZINE-N, SYNTHETIC CLZ-N CLZN-N H COELENTERATE LUCIFERIN NATIVE COELENTERATE LUCIFERIN CLZN [Coelenterazine, Native] Luciferin, Preluciferin, Coelenterazine luciferin Coelenterazine Native 95% CLZN, 3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one 8-benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)iMidazo[1,2-a]py enterazine 8-benzyl-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-7H-imidazo[1,2-a]pyrazin-3-one Coelenterazine Native (CLZN) ex. Aequorea Sp., 95% 8-benzyl-2- (4-hydroxybenzyl) -6- (4-hydroxyphenyl) imidazolo [1,2-a] pyrazine-3 (7H) - one Calcium ion fluorescent probe for colistin Natural Coercetin Coelenterazine, natural Coelenterazine - lyopholised 55779-48-1 C26H21N3O3 Coelenterazine Sampler Kit Coelenterazine Derivatives Fluorescent Probes, Labels, Particles and Stains Fluorescent Labels Intracellular Calcium Signaling Luminescent Other Fluorescent Labels Cell Signaling and Neuroscience Cell Biology Calcium Probes