Trigonelline hydrochloride
- CAS No.
- 6138-41-6
- Chemical Name:
- Trigonelline hydrochloride
- Synonyms
- SKL600;Trigoneline HCl;TRIGONELLINE HCL;EINECS 228-119-5;TIMTEC-BB SBB000182;Trigonelline hydroch;Trigonelline chloride;Gynesine Hydrochloride;Fenugreek hydrochloride;Coffearine Hydrochloride
- CBNumber:
- CB9168394
- Molecular Formula:
- C7H8ClNO2
- Molecular Weight:
- 173.6
- MDL Number:
- MFCD00077250
- MOL File:
- 6138-41-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| TRIGONELLINE HYDROCHLORIDE AldrichCPR | S414255 | 1 unit | $185 |
| Trigonelline chloride phyproof? Reference Substance | PHL80548 | 25MG | $292 |
| Trigonelline hydrochloride analytical standard | 61407 | 100mg | $114 |
| TRIGONELLINE HYDROCHLORIDE Aldrich | S414255 | 1g | $179 |
| Trigonelline Hydrochloride >98.0%(HPLC)(T) | T1429 | 5g | $199 |
| More product size | |||
| Melting point | ~260 °C (dec.) |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Methanol (Slightly), Water |
| form | Solid |
| color | White to Off-White |
| Merck | 14,9694 |
| BRN | 3734169 |
| Stability | Hygroscopic |
| InChI | InChI=1S/C7H7NO2.ClH/c1-8-4-2-3-6(5-8)7(9)10;/h2-5H,1H3;1H |
| InChIKey | TZSYLWAXZMNUJB-UHFFFAOYSA-N |
| SMILES | C1=[N+](C)C=CC=C1C([O-])=O.[H]Cl |
| CAS DataBase Reference | 6138-41-6(CAS DataBase Reference) |
| FDA UNII | 89A86B74I9 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xi |
|---|---|
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| HS Code | 29333990 |
Trigonelline hydrochloride price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S414255 | TRIGONELLINE HYDROCHLORIDE AldrichCPR | 6138-41-6 | 1 unit | $185 | 2025-07-31 | Buy |
| Sigma-Aldrich | PHL80548 | Trigonelline chloride phyproof? Reference Substance | 6138-41-6 | 25MG | $292 | 2025-07-31 | Buy |
| Sigma-Aldrich | 61407 | Trigonelline hydrochloride analytical standard | 6138-41-6 | 100mg | $114 | 2025-07-31 | Buy |
| Sigma-Aldrich | S414255 | TRIGONELLINE HYDROCHLORIDE Aldrich | 6138-41-6 | 1g | $179 | 2024-03-01 | Buy |
| TCI Chemical | T1429 | Trigonelline Hydrochloride >98.0%(HPLC)(T) | 6138-41-6 | 5g | $199 | 2025-07-31 | Buy |
Trigonelline hydrochloride Chemical Properties,Uses,Production
Description
Trigonelline hydrochloride (N-methylnicotinic acid betaine hydrochloride) is a betaine type pyrimidine alkaloid found in various seeds, including coffee beans. Trigonelline is synthesized from nicotinic acid in many plant species. It has been reported that trigonelline has diverse biological activities, such as hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities. (The product is for research purpose only.)
Uses
Trigonelline (chloride) is an alkaloid found in plants and coffee. Trigonelline is a product of niacin metabolism that is excreted in urine.
in vivo
Trigonelline chloride decreases bone mineralization and tends to worsen bone mechanical properties in streptozotocin-induced diabetic rats. In nicotinamide/streptozotocin-treated rats, Trigonelline chloride significantly increases bone mineral density (BMD) and tends to improve cancellous bone strength. Trigonelline chloride differentially affects the skeletal system of rats with streptozotocin-induced metabolic disorders, intensifying the osteoporotic changes in streptozotocin-treated rats and favorably affecting bones in the non-hyperglycemic (nicotinamide/streptozotocin-treated) rats[2].
target
Beta Amyloid
IC 50
HSV-1
References
Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease (a review)
J. Zhou, L. Chan, S. Zhou, Curr. Med. Chem. 2012, 19, 3523.
A Review on Biosynthesis, Analytical Techniques, and Pharmacological Activities of Trigonelline as a Plant Alkaloid
N. Mohamadi, F. Sharififar, M. Pournamdari, M. Ansari, J. Dietary Suppl. 2018, 15, 207.
Trigonelline hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi an Biohorlden Industry Trade Co Ltd | +86-18829283179 +86-13636819721 | sales@horlden.com | China | 317 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16516 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21620 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
View Lastest Price from Trigonelline hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-15 | Trigonelline chloride
6138-41-6
|
US $50.00-37.00 / mg | 99.31% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-10-13 | Trigonelline chloride
6138-41-6
|
US $3.00-9.00 / KG | 0.1KG | 99% | g-kg-tons, free sample is available | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-09-25 | Trigonelline hydrochloride
6138-41-6
|
US $0.00-0.00 / kg | 1kg | 99% | 1000 kg | Xi an Biohorlden Industry Trade Co Ltd |
-
- Trigonelline chloride
6138-41-6
- US $50.00-37.00 / mg
- 99.31%
- TargetMol Chemicals Inc.
-
- Trigonelline chloride
6138-41-6
- US $3.00-9.00 / KG
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- Trigonelline hydrochloride
6138-41-6
- US $0.00-0.00 / kg
- 99%
- Xi an Biohorlden Industry Trade Co Ltd
