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4ALPHA-PHORBOL 12,13-DIDECANOATE

CAS No.
27536-56-7
Chemical Name:
4ALPHA-PHORBOL 12,13-DIDECANOATE
Synonyms
4a-PDD;4ALPHA-PDD;4α-Phorbol 12;13-didecanoate;4alphaPDD,4alpha PDD;-Phorbol12,13-didecanoate;4α-phorbol 12-13-dicaprinate;4a-Phorbol-12,13-didecanoate;4α-Phorbol 12,13-didecanoate;4±-Phorbol 12,13-didecanoate
CBNumber:
CB9171479
Molecular Formula:
C40H64O8
Molecular Weight:
672.93
MDL Number:
MFCD00036737
MOL File:
27536-56-7.mol
MSDS File:
SDS
Last updated:2025-07-19 12:08:47

4ALPHA-PHORBOL 12,13-DIDECANOATE Properties

storage temp. -20°C
solubility DMSO: soluble
form solid
color white
BRN 2514324
UNSPSC Code 12352211
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H300+H310+H330-H314-H317-H334-H351
Precautionary statements  P201-P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  T+
Risk Statements  26/27/28-40-43
Safety Statements  36/37/39-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
8-10
HazardClass  6.1(b)
PackingGroup  III
NFPA 704
0
4 0

4ALPHA-PHORBOL 12,13-DIDECANOATE price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 524394 4α-Phorbol-12,13-didecanoate 27536-56-7 1mg $129 2025-07-31 Buy
Sigma-Aldrich 524394 4α-Phorbol-12,13-didecanoate 27536-56-7 5mg $489 2025-07-31 Buy
Cayman Chemical 20446 4α-Phorbol 12,13-didecanoate ≥99% 27536-56-7 1mg $100 2024-03-01 Buy
Cayman Chemical 20446 4α-Phorbol 12,13-didecanoate ≥99% 27536-56-7 5mg $425 2024-03-01 Buy
Sigma-Aldrich P8014 4α-Phorbol 12,13-didecanoate solid 27536-56-7 1mg $210 2025-07-31 Buy
Product number Packaging Price Buy
524394 1mg $129 Buy
524394 5mg $489 Buy
20446 1mg $100 Buy
20446 5mg $425 Buy
P8014 1mg $210 Buy

4ALPHA-PHORBOL 12,13-DIDECANOATE Chemical Properties,Uses,Production

Uses

4α-Phorbol 12,13-didecanoate has been used as a transient receptor potential vanilloid 4 (TRPV4) agonist:

  • to study its effects on Madin-Darby canine kidney (MDCK) cells
  • to study its effects on Ca2+ influx in mice fallopian tubal cells
  • to study its effects on hind paw swelling in mice

Definition

ChEBI: 4alpha-phorbol 12,13-didecanoate is a phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted to the corresponding decanoate esters. A Trpv4-specific ligand. It has a role as a TRPV4 agonist. It is a phorbol ester, a decanoate ester, a tertiary alpha-hydroxy ketone, a diester and a primary allylic alcohol.

Biochem/physiol Actions

4α-Phorbol 12,13-didecanoate is a transient receptor potential vanilloid 4 (TRPV4) agonist. It promotes extracellular calcium influx into the cells.

4ALPHA-PHORBOL 12,13-DIDECANOATE Preparation Products And Raw materials

Raw materials

Preparation Products

4ALPHA-PHORBOL 12,13-DIDECANOATE Suppliers

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49917 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32431 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40066 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739 info@dycnchem.com China 53900 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58

View Lastest Price from 4ALPHA-PHORBOL 12,13-DIDECANOATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4alpha-PDD pictures 2025-07-19 4alpha-PDD
27536-56-7
US $0.00-0.00 / mg 10g TargetMol Chemicals Inc.
  • 4alpha-PDD pictures
  • 4alpha-PDD
    27536-56-7
  • US $0.00-0.00 / mg
  • TargetMol Chemicals Inc.
4ALPHA-PDD 4ALPHA-PHORBOL 12-13-DICAPRINATE 4ALPHA-PHORBOL 12,13-DIDECANOATE 4a-Phorbol-12,13-didecanoate 4A-PHORBOL 12,13-DIDECANOATE WEAK PROTEI N KINASE C 4α-phorbol 12-13-dicaprinate 4A-PHORBOL 12,13-DIDECANOATE, 99+% phorbol (4alpha-) 12,13-didecanoate 4α-Phorbol 12-13-dicaprinate, 4αPDD 4alpha-Phorbol 12,13-dideconate Decanoic acid, 1,1A,1B,4,4A,5,7A,7B,8,9-decahydro-4A,7B-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9ah-cyclopropa(3,4)benz(1,2-E)azulene-9,9A-diyl ester, (1ar-(1aalpha,1bbeta,4aalpha,7aalpha,7balpha,8alpha,9beta,9aalpha))- 4-alpha-Phorbol 12,13-Didecanoate >99% 4α-Phorbol 12,13-Didecanoate, >99% 4a-PDD 4α-Phorbol-12,13-didecanoate - CAS 27536-56-7 - Calbiochem Decanoic acid, 1,1'-[(1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl] ester 4α-Phorbol 12,13-didecanoate -Phorbol12,13-didecanoate 13-didecanoate 4α-Phorbol 12 4alphaPDD,4alpha PDD 4alpha-Phorbol 12,13-didecanoate solid 4±-Phorbol 12,13-didecanoate 27536-56-7 C40H64O8 Kinase/Phosphatase Biology Serine/Threonine Kinase Activators Protein Kinase C (PKC) Cell Signaling and Neuroscience Cell Biology BioChemical metabolite