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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

CAS No.
4465-65-0
Chemical Name:
4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Synonyms
Epianhydrotetracycline;Aureomycin EP impurity K;Tetracycline Impurity D(EP);Chlortetracycline Impurity 16;Tetracycline EP Impurity D HCl;Tetracycline 4-Epi Anhydro HCl;Chlortetracycline EP Impurity I;Epianhydrotetracycline hydrochloride;4-Epianhydrotetracycline HCl, EvoPure;4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
CBNumber:
CB9171671
Molecular Formula:
C22H23ClN2O7
Molecular Weight:
462.88
MDL Number:
MFCD00151455
MOL File:
4465-65-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-19 15:07:56
Product description Number Pack Size Price
4-Epianhydrotetracycline hydrochloride European Pharmacopoeia (EP) Reference Standard E0400000 25 mg $241
4-Epianhydrotetracycline hydrochloride VETRANAL?, analytical standard 37921 100mg $332
4-Epianhydrotetracycline hydrochloride United States Pharmacopeia (USP) Reference Standard 1236506 50mg $1290
Epianhydrotetracycline (hydrochloride) ≥90% 27954 1mg $36
Epianhydrotetracycline (hydrochloride) ≥90% 27954 5mg $160

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Properties

Melting point 220 °C
storage temp. -20°C Freezer
solubility DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 0.25 mg/ml
form Powder
color Orange
BRN 3840711
Major Application clinical testing
InChIKey XBSQEFHDCDFNJU-PFRKANOHNA-N
SMILES O[C@@]12C(C(C(=O)N)=C(O)[C@H](N(C)C)[C@]1([H])CC1C(=C3C=CC=C(O)C3=C(O)C=1C2=O)C)=O.Cl |&1:1,9,13,r|
FDA UNII 06Y7HM8DBA
EPA Substance Registry System 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4R,4aS,12aS)- (4465-65-0)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xn
Risk Statements  63-36-22
Safety Statements  36/37/39-26
WGK Germany  3
HS Code  29413000
Storage Class 11 - Combustible Solids

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E0400000 4-Epianhydrotetracycline hydrochloride European Pharmacopoeia (EP) Reference Standard 4465-65-0 25 mg $241 2026-04-30 Buy
Sigma-Aldrich 37921 4-Epianhydrotetracycline hydrochloride VETRANAL?, analytical standard 4465-65-0 100mg $332 2026-04-30 Buy
Sigma-Aldrich 1236506 4-Epianhydrotetracycline hydrochloride United States Pharmacopeia (USP) Reference Standard 4465-65-0 50mg $1290 2026-04-30 Buy
Cayman Chemical 27954 Epianhydrotetracycline (hydrochloride) ≥90% 4465-65-0 1mg $36 2026-04-30 Buy
Cayman Chemical 27954 Epianhydrotetracycline (hydrochloride) ≥90% 4465-65-0 5mg $160 2026-04-30 Buy
Product number Packaging Price Buy
E0400000 25 mg $241 Buy
37921 100mg $332 Buy
1236506 50mg $1290 Buy
27954 1mg $36 Buy
27954 5mg $160 Buy

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

orange powder

Uses

An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study.

Uses

Epianhydrotetracycline is a secondary degradation product formed by epimerisation of tetracycline and dehydration at the C6 position to aromatise the B ring. Epianhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, epianhdrotetracycline is considered biologically active and is thought responsible for aspects tetracycline toxicity.

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Suppliers

Global( 82)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
Guangzhou PI PI BIOTECH INC
+86-86-020-81716320 +8613602409664 Sales@pipitech.com China 973 55
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19936 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9996 58
Shaanxi Dideu New Materials Co. Ltd
+86-18192503167 18192503167 1036@dideu.com China 7915 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739 info@dycnchem.com China 53803 58
Hubei widely chemical technology Co., Ltd. 180-62128043 18062128043 18163321995@163.com China 1894 64
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50

View Lastest Price from 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Epianhydrotetracycline hydrochloride pictures 2026-05-19 4-Epianhydrotetracycline hydrochloride
4465-65-0
10g TargetMol Chemicals Inc.
4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE pictures 2025-12-01 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
4465-65-0
1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-epianhydrotetracyclinehydrochloride’canbeusedassecondarystandard’ 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Lymecycline Impurity 4(Lymecycline EP Impurity D) Tetracycline EP Impurity D HCl (4R,4AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,12,12A-HEXAHYDRO-3,10,11,12A-TETRAHYDROXY-6-METHYL-1,12-DIOXO-2-NAPHTHACENECARBOXAMIDE MONOHYDROCHLORIDE 4-Epianhydrotetracycline hydrochloride, 'can be used as a secondary standard', 97% 4-Epianhydroustetracycline hydrochloride 4-Epianhydrotetracycline hydrochloride,97%,'can be used as a secondary standard' 4-Epianhydrotetracycline Hydrochloride (50 mg) (4R,4aS,12aS)-4-(DiMethylaMino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-Methyl-1,12-dioxo-2-naphthacenecarboxaMide Hydrochloride Epianhydrotetracycline hydrochloride 4-Epianhydrotetracycline hydrochloride CRS Tetracycline 4-Epi Anhydro HCl Chlortetracycline EP Impurity I Aureomycin EP impurity K 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE USP/EP/BP 4-Epianhydrotetracycline Hydrochloride (1236506) (4R,4aS,12aS)-4-(dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide (4-epianhydrotetracycline) 4-Epianhydrotetracycline HCl, EvoPure 4-epi-Anhydrotetracycline hydrochloride in methanol C13174500 4-EpianhydrotetracyclinEhydrochlor Tetracycline EP Impurity D (Chlortetracycline EP Impurity I, Lymecycline EP Impurity D, 4-Epianhydrotetracycline) 4-Epianhydrotetracycline hydrochloride hydrate TETRACYCLINE EP IMPURITY D/ 4-EPIANHYDRO TETRACYCLINE HYDROCHLORIDE 4-Epianhydrotetracycline hydrochloride RS Tetracycline Impurity D(EP) Chlortetracycline Impurity 16 Epianhydrotetracycline 4465-65-0 C22H22N2O7HCl C22H23ClN2O7 Intermediates & Fine Chemicals Pharmaceuticals