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4-N-BOC-Aminopiperidine

4-N-BOC-Aminopiperidine structure

CAS No.: 73874-95-0

Chemical Name:: 4-N-BOC-Aminopiperidine

Synonyms: TERT-BUTYL PIPERIDIN-4-YLCARBAMATE;tert-butyl N-(piperidin-4-yl)carbaMate;4-(N-BOC-AMINO)PIPERIDINE;tert-Butyl N-(4-piperidyl)carbaMate;PIPERIDIN-4-YL-CARBAMIC ACID TERT-BUTYL ESTER;4-BOC-AMINOPIPERIDINE;Prucapride 11;BUTTPARK 90\06-01;4-N-BOC-AMinopiperid;BOC-4-AMINOPIPERIDINE

CBNumber:: CB9192199

Molecular Formula:: C10H20N2O2

Molecular Weight:: 200.28

MDL Number:: MFCD00798171

MOL File:: 73874-95-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-21 10:31:43

Product description	Number	Pack Size	Price
4-(N-Boc-amino)piperidine 96%	540935	1g	$29.7
4-(N-Boc-amino)piperidine 96%	540935	5g	$36.5
4-(tert-Butoxycarbonylamino)piperidine >98.0%(GC)(T)	B2319	1g	$19
4-(tert-Butoxycarbonylamino)piperidine >98.0%(GC)(T)	B2319	5g	$27
4-(N-Boc-amino)piperidine ≥95%	30398	1g	$41
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4-N-BOC-Aminopiperidine Properties

Melting point	162-166 °C(lit.)
Boiling point	80°C/0.05mm
Density	1.02±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	12.39±0.20(Predicted)
form	Crystalline Powder
color	Off-white
Sensitive	Air Sensitive
InChI	InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-8-4-6-11-7-5-8/h8,11H,4-7H2,1-3H3,(H,12,13)
InChIKey	CKXZPVPIDOJLLM-UHFFFAOYSA-N
SMILES	C(OC(C)(C)C)(=O)NC1CCNCC1
CAS DataBase Reference	73874-95-0(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37/39

WGK Germany

HazardClass

IRRITANT

HS Code

29339900

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
3		0

4-N-BOC-Aminopiperidine price More Price(70)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	540935	4-(N-Boc-amino)piperidine 96%	73874-95-0	1g	$29.7	2026-04-30	Buy
Sigma-Aldrich	540935	4-(N-Boc-amino)piperidine 96%	73874-95-0	5g	$36.5	2026-04-30	Buy
TCI Chemical	B2319	4-(tert-Butoxycarbonylamino)piperidine >98.0%(GC)(T)	73874-95-0	1g	$19	2026-04-30	Buy
TCI Chemical	B2319	4-(tert-Butoxycarbonylamino)piperidine >98.0%(GC)(T)	73874-95-0	5g	$27	2026-04-30	Buy
Cayman Chemical	30398	4-(N-Boc-amino)piperidine ≥95%	73874-95-0	1g	$41	2026-04-30	Buy

Product number	Packaging	Price	Buy
540935	1g	$29.7	Buy
540935	5g	$36.5	Buy
B2319	1g	$19	Buy
B2319	5g	$27	Buy
30398	1g	$41	Buy

4-N-BOC-Aminopiperidine Chemical Properties,Uses,Production

Description

4-(N-Boc-amino)piperidone may be used as a functionalization reagent for introduction of a primary and a tertiary amino group to poly(2-isopropyl-2-oxazoline. It can also be used as pharma building block. It is used in the synthesis of a piperidine-4-carboxamide CCR5 antagonist with potent anti-HIV 1-activity. It is an intermediate for the synthesis of various pharmaceutical and biologically active compounds, including inhibitors and therapeutic agents. It is used for the synthesis of diphenyl purine derivatives as peripherally selective cannabinoid receptor 1 Antagonists.

Chemical Properties

off-white crystalline powder

Uses

Pharma building block.

General Description

4-(N-Boc-amino)piperidone is a piperidone derivative.

Synthesis

73889-19-7

73874-95-0

General procedure for the synthesis of 4-tert-butoxycarbonylaminopiperidine from tert-butyl (1-benzylpiperidin-4-yl)carbamate: N-butyl-1-benzylpiperidin-4-ylcarbamate (3.80 g, 13.1 mmol) was dissolved in 26 mL of methanol in a 100 mL reaction vessel. A catalytic amount of 10% palladium/carbon (Pd/C) was added. The reaction was stirred under hydrogen atmosphere for 12 hours. Upon completion of the reaction, the palladium/carbon catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure to remove the solvent. The resulting residue was purified by silica gel column chromatography to afford 4-tert-butoxycarbonylaminopiperidine (2.64 g, 99% yield). The product was confirmed by 1H-NMR (200 MHz, CD3OD): δ 1.36 (s, 9H), 1.84-2.36 (m, 4H), 2.74 (m, 2H), 3.42 (m, 2H), 3.60 (br, 1H).LC/MS analysis showed the [M+H]+ peak as 201.

References

[1] Patent: WO2008/54154, 2008, A1. Location in patent: Page/Page column 33; 34; 76; 77; 162-164
[2] Patent: WO2007/52938, 2007, A1. Location in patent: Page/Page column 18
[3] Journal of Medicinal Chemistry, 1999, vol. 42, # 14, p. 2706 - 2715
[4] Patent: WO2007/46550, 2007, A1. Location in patent: Page/Page column 117
[5] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 24, p. 5345 - 5352

4-N-BOC-Aminopiperidine synthesis

Synthesis of 4-N-BOC-Aminopiperidine from 1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98

4-N-BOC-Aminopiperidine Preparation Products And Raw materials

Raw materials

1,1'-Carbonyldiimidazole Hydrazinium hydroxide solution Acetone Di-tert-butyl dicarbonate Potassium carbonate

2,3-DICHLORO-5,8-DIHYDROXY-1,4-NAPHTHOQUINONE Chloroform Palladium Sodium nitrite Methyl isonipecotate

Benzyl bromide Ethyl acetate Hydrochloric acid Isonipecotic acid Bromine

Acetic acid Methanol BENZYL 4-ISOCYANATOTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE 4-Amino-1-benzylpiperidine

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Preparation Products

4-N-BOC-Aminopiperidine Suppliers

Global( 520)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58
Anhui Yiao New Material Technology Co., Ltd	+86-18033737140 +86-17354101231	sales1@hbganmiao.com	China	227	58
Xiamen Wonderful Bio Technology Co., Ltd.	+8613043004613	Sara@xmwonderfulbio.com	China	283	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29640	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21588	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1001	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29816	58

Supplier	Advantage
sgtlifesciences pvt ltd	58
Anhui Yiao New Material Technology Co., Ltd	58
Xiamen Wonderful Bio Technology Co., Ltd.	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shanxi Naipu Import and Export Co.,Ltd	58
career henan chemical co	58

View Lastest Price from 4-N-BOC-Aminopiperidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-21	4-(N-Boc-amino)piperidine 73874-95-0	US $513.00 / g			10g	TargetMol Chemicals Inc.
2025-11-18	4-N-BOC-Aminopiperidine 73874-95-0	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2025-06-20	4-Boc-aminopiperidine 73874-95-0	US $1.00 / Kg/Bag	1Kg/Bag	99.5% HPLC	500KG/MONTH	Hebei Yanxi Chemical Co., Ltd.

4-(N-Boc-amino)piperidine
73874-95-0
US $513.00 / g
TargetMol Chemicals Inc.

4-N-BOC-Aminopiperidine
73874-95-0
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-Boc-aminopiperidine
73874-95-0
US $1.00 / Kg/Bag
99.5% HPLC
Hebei Yanxi Chemical Co., Ltd.

4-N-BOC-Aminopiperidine Spectrum

4-N-BOC-Aminopiperidine(73874-95-0)¹HNMR 4-N-BOC-Aminopiperidine(73874-95-0)IR

73874-95-0(4-N-BOC-Aminopiperidine)Related Search:

1-Aminopiperidine DROPERIDOL Haloperidol 3-N-Boc-aminopiperidine tert-butyl thiazol-4-ylcarbamate

(1R,4R)-(4-MethylaMino-cyclohexyl)-carbaMic acid tert-butyl ester 1-Oxa-6-azaspiro[3.3]heptane-6-carboxylic acid, 3,3-diMethyl-, 1,1-diMethylethyl ester tert-butyl((5-carbamoyl-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate DI-TERT-BUTYL ETHER Carbamic acid, N-methyl-N-[(3-nitrophenyl)methyl]-, 1,1-dimethylethyl ester

4-AMINO-1-BOC-PIPERIDINE-4-CARBOXYLIC ACID 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONOBENZYL ESTER 4-N-Boc-4-N-Methyl-aminopiperidine 1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER

Diphenoxylate (R)-3-(Boc-Amino)piperidine (R)-1-Benzyl-3-N-Boc-aminopiperidine

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4-(TERT-BUTOXYCARBONYLAMINO)PIPERIDINE 4-N-TERT-BOC-AMINO PIPERIDINE 4-N-(TERT-BUTOXYCARBONYL)AMINOPIPERIDINE 4-BOC-AMINOPIPERIDINE 4-AMINOPIPERIDINE, 4-BOC PROTECTED 4-(tert-ButoxycarbonylaMino)piperidine, 98.0%(GC&T CARBAMIC ACID, 4-PIPERIDINYL-, 1,1-DIMETHYLETHYL ESTER BUTTPARK 90\06-01 BOC-4-AMINOPIPERIDINE 4 - bok - aMino piperidine 4-N-BOC-AMinopiperidine SynonyMs 4-N-(tert-Butoxycarbonyl)aMinopiperidine 4-(Boc-amino)piperidine,96% Carbamic acid, N-4-piperidinyl-, 1,1-dimethylethyl ester 4-(N-Boc-amino)piperidine 96% N-(4-piperidinyl)carbamic acid tert-butyl ester N-(4-piperidyl)carbamic acid tert-butyl ester 1,1-Dimethylethyl (4-piperidinyl)carbamate 4-((1-tert-Butoxycarbonyl)amino)piperidine Carbamic acid, 4-piperidinyl-, 1,1-dimethylethyl ester (9CI) 4-T-Boc-Amino Piperidine 4-N-BOC-AMINO-PIPERIDINE (OR) 4(TERT BOC)-AMINO PIPERIDINE (GROUP-B, SRL NO:1124) tert-Butyl 4-piperidinylcarbamate 4-Tert-Boc-AminoPiperdine 4-Tert-Boc-Amino-Piperidine PIPERIDIN-4-YL-CARBAMIC ACID TERT-BUTYL ESTER 4-N-1-BOC-AMINOPIPERIDINE BOC (PROTECTED)-4-AMINO PIPERIDINE 4-BOC-AMINO PIPERIDINE,98% 4-BOC-AMINO PIPERDINE tert-butyl N-(4-piperidinyl)carbamate 4-N-BOC-Aminopiperidine,98% tert-Butyl N-(4-piperidyl)carbaMate tert-butyl 1-aMinopiperidine-4-carboxylate 4-N-BOC-AMinopiperidine, 98% 5GR 4-N-BOC-AMinopiperid 4-(tert-ButoxycarbonylaMino)piperidine piperidin-4-yl-carbaMic acid tert-butyl ester hydrochloride tert-Butyl (piperidin-4-yl)carbamate, 4-[(tert-Butoxycarbonyl)amino]piperidine 4-Aminopiperidine, 4-BOC protected 97% 4-N-BOC-Aminopiperidine CAS:73874-95-0 4-(tert-Butoxycarbonylamino)piperidine > 4-(N-BOC-AMINO)PIPERIDINE High Purity 4-N-Boc-Aminopperidine 4-N-BOC-Aminopiperidine ISO 9001：2015 REACH 4-N-BOC-AMINO-PIPERIDINE (OR) 4(TER T BOC)-AMINO PIPERIDINE N-BOC-4-Aminopiperidine pure, 97% 4-N-B0C- Aminopiperidine Prucapride 11 Prucalopride Impurity 46 4-(N-Boc-amino)piperidine 4-(N-Boc-amino)piperidine, 96% 4-(N-BOC-AMINO)PIPERIDINE TERT-BUTYL PIPERIDIN-4-YLCARBAMATE tert-butyl N-(piperidin-4-yl)carbaMate 73874-95-0 C10H21N2O2 Heterocyclic Building Blocks Piperidines