Isobutyl acetoacetate
- CAS No.
- 7779-75-1
- Chemical Name:
- Isobutyl acetoacetate
- Synonyms
- ACIB;ISOBUTYL ACETOACETATE;Isobutyl 3-oxobutanoate;Isobutyl Acetoacetate >Isobutyl acetoacetate(IBAA);2-Methylpropyl acetoacetate;ACETOACETIC ACID ISOBUTYL ESTER;Isobutyl acetoacetate USP/EP/BP;Isobutyl Acetoacetate, 98.0%(GC);3-Oxobutyric acid isobutyl ester
- CBNumber:
- CB9234174
- Molecular Formula:
- C8H14O3
- Molecular Weight:
- 158.2
- MDL Number:
- MFCD00059349
- MOL File:
- 7779-75-1.mol
- MSDS File:
- SDS
| Melting point | 177-179 °C(Solv: ethyl ether (60-29-7)) |
|---|---|
| Boiling point | 100 °C/22 mmHg (lit.) |
| Density | 0.98 g/mL at 25 °C (lit.) |
| refractive index |
n |
| FEMA | 2177 | ISOBUTYL ACETOACETATE |
| Flash point | 173 °F |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| pka | 10?+-.0.46(Predicted) |
| form | liquid |
| color | clear |
| Odor | at 10.00 % in dipropylene glycol. sweet wine brandy fruity |
| Odor Type | fruity |
| JECFA Number | 597 |
| BRN | 1761405 |
| LogP | 1.60 |
| CAS DataBase Reference | 7779-75-1(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | ISOBUTYL ACETOACETATE |
| FDA 21 CFR | 172.515 |
| FDA UNII | 5HI9DAL68Z |
| NIST Chemistry Reference | Butanoic acid, 3-oxo-, 2-methylpropyl ester(7779-75-1) |
| EPA Substance Registry System | Butanoic acid, 3-oxo-, 2-methylpropyl ester (7779-75-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227-H315-H319 | |||||||||
| Precautionary statements | P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2918.30.9000 | |||||||||
| NFPA 704 |
|
Isobutyl acetoacetate price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 00483 | Isobutyl acetoacetate ≥98.0% (GC) | 7779-75-1 | 100ml | $66.3 | 2025-07-31 | Buy |
| Sigma-Aldrich | 688657 | Isobutyl acetoacetate Lonza quality, ≥97.0% (GC) | 7779-75-1 | 1kg | $101 | 2023-06-20 | Buy |
| TCI Chemical | A0814 | Isobutyl Acetoacetate >98.0%(GC) | 7779-75-1 | 25mL | $20 | 2025-07-31 | Buy |
| Sigma-Aldrich | 688657 | Isobutyl acetoacetate Lonza quality, ≥97.0% (GC) | 7779-75-1 | 180kg | $3820 | 2022-05-15 | Buy |
| TRC | I780045 | Isobutyl Acetoacetate | 7779-75-1 | 50g | $120 | 2021-12-16 | Buy |
Isobutyl acetoacetate Chemical Properties,Uses,Production
Description
Isobutyl acetoacetate has a sweet, winey, brandy-like odor and a sweet and slightly fruity flavor. May be prepared from isobutyl acetate by heating in the presence of sodium isobutylate.
Chemical Properties
Isobutyl acetoacetate has a sweet, winy, brandy-like odor and a sweet and slightly fruity flavor.
Chemical Properties
Isobutyl acetoacetate is a clear colorless liquid. Insoluble in water, soluble in alcohol and oils. B.P. approximately 196℃. The odor is somewhat fresher, not as "fermented" as that of the n-But yiester, while the taste of the iso-Butylester is somewhat less sweet. In general, the former is preferred for “winey” effects, while this (latter) is preferred for fruity effects, and partly as a fixative for the more volatile esters used in hard candy flavoring etc. Concentrations are usually around 25 ppm.
Uses
Isobutyl acetoacetate is used as intermediate for the production of pharmaceuticals (e.g. Nisoldipine). Product Data Sheet
Uses
Isobutyl Acetoacetate is a building block that has been used as a reactant in the preparation of b-annulated 1,4-dihydropyridine derivatives as TGFβ signaling inhibitors.
Definition
ChEBI: 2-Methylpropyl 3-oxobutanoate is an oxo carboxylic acid.
Preparation
From isobutyl acetate by heating in the presence of sodium isobutylate. Or by Claisen condensation of iso-ButyI acetate with Ethylacetate, using Sodium ethoxide catalyst.
Isobutyl acetoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20424 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| LUYUNJIA CHEMISTRY XIAMEN LIMITED | +86-592-5360779 +86-13055435203 | China | 5988 | 58 | |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
View Lastest Price from Isobutyl acetoacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | Isobutyl acetoacetate
7779-75-1
|
US $1.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- Isobutyl acetoacetate
7779-75-1
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
