8-HYDROXY-QUINOLINE-5-CARBALDEHYDE
- CAS No.
- 2598-30-3
- Chemical Name:
- 8-HYDROXY-QUINOLINE-5-CARBALDEHYDE
- Synonyms
- 5g 1 pcs;IFLAB-BB F2108-0159;Indacaterol Impurity 29;Indacaterol Impurity 22;5-Formyl-8-hydroxyquinoline;8-HYDROXY-QUINOLINE-5-CARBALDEHYDE;8-Hydroxyquinoline-5-carboxaldehyde;8-hydroxy-5-Quinolinecarboxaldehyde;5-Quinolinecarboxaldehyde,8-hydroxy-
- CBNumber:
- CB9243130
- Molecular Formula:
- C10H7NO2
- Molecular Weight:
- 173.17
- MDL Number:
- MFCD03425064
- MOL File:
- 2598-30-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 8-hydroxy-quinoline-5-carbaldehyde AldrichCPR | CDS018146 | 10 mg | $73.1 |
| 8-Hydroxyquinoline-5-carbaldehyde | A430530 | 100mg | $70 |
| 8-Hydroxyquinoline-5-carbaldehyde | 2196AB | 1g | $286 |
| 8-Hydroxyquinoline-5-carbaldehyde | 2196AB | 100mg | $97 |
| 8-HYDROXY-QUINOLINE-5-CARBALDEHYDE 95.00% | CHM0299155 | 5MG | $505.49 |
| Melting point | 178 °C |
|---|---|
| Boiling point | 383.1±22.0 °C(Predicted) |
| Density | 1.364±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.88±0.10(Predicted) |
| color | Green |
| InChI | InChI=1S/C10H7NO2/c12-6-7-3-4-9(13)10-8(7)2-1-5-11-10/h1-6,13H |
| InChIKey | LIADJWREMDHKHQ-UHFFFAOYSA-N |
| SMILES | N1C2C(=C(C=O)C=CC=2O)C=CC=1 |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H335-H319 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
8-HYDROXY-QUINOLINE-5-CARBALDEHYDE price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS018146 | 8-hydroxy-quinoline-5-carbaldehyde AldrichCPR | 2598-30-3 | 10 mg | $73.1 | 2025-07-31 | Buy |
| TRC | A430530 | 8-Hydroxyquinoline-5-carbaldehyde | 2598-30-3 | 100mg | $70 | 2021-12-16 | Buy |
| AK Scientific | 2196AB | 8-Hydroxyquinoline-5-carbaldehyde | 2598-30-3 | 1g | $286 | 2021-12-16 | Buy |
| AK Scientific | 2196AB | 8-Hydroxyquinoline-5-carbaldehyde | 2598-30-3 | 100mg | $97 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0299155 | 8-HYDROXY-QUINOLINE-5-CARBALDEHYDE 95.00% | 2598-30-3 | 5MG | $505.49 | 2021-12-16 | Buy |
8-HYDROXY-QUINOLINE-5-CARBALDEHYDE Chemical Properties,Uses,Production
Uses
8-Hydroxyquinoline-5-carbaldehyde is used in preparation of Polycyclic compounds.
Synthesis
148-24-3
67-66-3
2598-30-3
8-Hydroxyquinoline (5 g, 0.034 mol) was dissolved in ethanol (50 mL), followed by the addition of sodium hydroxide (10 g, 0.25 mol) dissolved in water (15 mL). The mixed solution was heated to reflux and trichloromethane was added slowly and dropwise over 30 minutes. After continuing the reflux reaction for 20 h, ethanol and unreacted trichloromethane were removed by distillation under reduced pressure. The residue was dissolved in water (150 mL) and the pH was adjusted to slightly acidic with dilute hydrochloric acid. The resulting yellow solid was extracted with dichloromethane and the extract was purified by column chromatography (silica gel as stationary phase and dichloromethane/methanol as eluent) to give 8-hydroxyquinoline-5-carbaldehyde as a final white solid (115 mg, 0.67 mmol). The structure of the product was confirmed by 1H-NMR (CDCl3, 400 MHz) and 13C-NMR (DMSO-d6, 400 MHz): 1H-NMR δ = 10.16 (s, 1H), 9.71 (dd, 1H, J = 1.6Hz, 8.4Hz), 8.89 (dd, 1H, J = 1.6Hz, 4.0Hz), 8.02 (d , 1H, J = 8.0 Hz), 7.69 (q, 1H, J = 4.0 Hz), 7.30 (d, 1H, J = 8.0 Hz); 13C-NMR δ = 193.1, 160.5, 149.9, 141.1, 138.9, 133.9, 127.7, 125.5, 123.4, 111.7.
References
[1] Journal of Coordination Chemistry, 2012, vol. 65, # 9, p. 1632 - 1644
[2] Journal of Organic Chemistry, 2011, vol. 76, # 10, p. 3774 - 3781
[3] Journal of the Chilean Chemical Society, 2012, vol. 57, # 3, p. 1287 - 1291
[4] Farmaco, 1993, vol. 48, # 5, p. 615 - 636
[5] Gazzetta Chimica Italiana, 1995, vol. 125, # 2, p. 69 - 76
8-HYDROXY-QUINOLINE-5-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
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Preparation Products
8-HYDROXY-QUINOLINE-5-CARBALDEHYDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16516 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21618 | 55 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 11908 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49948 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
View Lastest Price from 8-HYDROXY-QUINOLINE-5-CARBALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-13 | 5-Quinolinecarboxaldehyde,8-hydroxy-
2598-30-3
|
US $2.00-6.00 / kg | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- 5-Quinolinecarboxaldehyde,8-hydroxy-
2598-30-3
- US $2.00-6.00 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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