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Gilenia

Gilenia structure

CAS No.: 162359-55-9

Chemical Name:: Gilenia

Synonyms: Gilenia;Fingomod;Fingolise;fingolimo;fenogliMod;Fingolimod;FingoliMod-D4;FingoliMod Base;Gilenia USP/EP/BP;Fingolimod(FTY720)

CBNumber:: CB92498299

Molecular Formula:: C19H33NO2

Molecular Weight:: 307.47

MDL Number:: MFCD14705150

MOL File:: 162359-55-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-22 18:57:36

Product description	Number	Pack Size	Price
Fingolimod for system suitability European Pharmacopoeia (EP) Reference Standard	Y0002058	10 mg	$164
Fingolimod	F1395	200MG	$66
Fingolimod	F1395	1G	$232
Fingolimod ≥98%	11975	5mg	$62
Fingolimod ≥98%	11975	10mg	$116
More product size

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Gilenia Properties

Melting point	103-105°
Boiling point	479.5±45.0 °C(Predicted)
Density	1.016
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	Chloroform (Very Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly,
pka	12.20±0.20(Predicted)
form	Solid
color	Off-White
InChI	InChI=1S/C19H33NO2/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22/h9-12,21-22H,2-8,13-16,20H2,1H3
InChIKey	KKGQTZUTZRNORY-UHFFFAOYSA-N
SMILES	C(O)C(N)(CCC1=CC=C(CCCCCCCC)C=C1)CO
FDA UNII	3QN8BYN5QF
ATC code	L04AA27
UNSPSC Code	41116107
NACRES	NA.24

Pharmacokinetic data

Protein binding	>99%
Volume of distribution	940-1460 litres
Biological half-life	6-9 days / Unchanged

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335-H402-H412

Precautionary statements

P261-P264-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501

target organs

Immune system

WGK Germany

WGK 3

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Repr. 2
Skin Irrit. 2
STOT RE 2

NFPA 704

	0
2		0

Gilenia price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0002058	Fingolimod for system suitability European Pharmacopoeia (EP) Reference Standard	162359-55-9	10 mg	$164	2026-04-30	Buy
TCI Chemical	F1395	Fingolimod	162359-55-9	200MG	$66	2026-04-30	Buy
TCI Chemical	F1395	Fingolimod	162359-55-9	1G	$232	2026-04-30	Buy
Cayman Chemical	11975	Fingolimod ≥98%	162359-55-9	5mg	$62	2026-04-30	Buy
Cayman Chemical	11975	Fingolimod ≥98%	162359-55-9	10mg	$116	2026-04-30	Buy

Product number	Packaging	Price	Buy
Y0002058	10 mg	$164	Buy
F1395	200MG	$66	Buy
F1395	1G	$232	Buy
11975	5mg	$62	Buy
11975	10mg	$116	Buy

Gilenia Chemical Properties,Uses,Production

Chemical Properties

white solid

Uses

Prophylaxis of organ rejection in patients receiving allogenic renal transplants (sphingosine-1-phosphate receptor).

Uses

Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.

Definition

ChEBI: An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimo is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate.

Clinical Use

Sphingosine 1-phosphate receptor modulator:
Treatment of highly active relapsing-remitting multiple sclerosis

Drug interactions

Potentially hazardous interactions with other drugs
Anti-arrhythmics: possible increased risk of bradycardia with amiodarone, disopyramide and dronedarone.
Antifungals: concentration increased by ketoconazole.
Beta-blockers: possibly increased risk of bradycardia.
Calcium channel blockers: possible increased risk of bradycardia with diltiazem and verapamil.

Metabolism

Transformed by reversible stereoselective phosphorylation to the pharmacologically active (S)-enantiomer of fingolimod phosphate. It is eliminated by oxidative biotransformation mainly via the cytochrome P450 4F2 isoenzyme and subsequent fatty acid-like degradation to inactive metabolites, and by formation of pharmacologically inactive non-polar ceramide analogues of fingolimod. The main enzyme involved in the metabolism of fingolimod is partially identified and may be either CYP4F2 or CYP3A4. 81% excreted as inactive metabolites in the urine and <2.5% in the faeces as metabolites and unchanged drug.

Gilenia synthesis

Synthesis of Gilenia from N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)acetamide

Gilenia Preparation Products And Raw materials

Raw materials

3-Furanmethanol, tetrahydro-3-nitro-5-(4-octylphenyl)- N-[2,2-DiMethyl-5-[2-(4-octylphenyl)ethyl]-1,3-dioxan-5-yl]carbaMic acid 1,1-diMethylethyl ester Propanedioic acid, 2-amino-2-[2-(4-octylphenyl)ethyl]-, 1,3-diethyl ester 2-NitrodeaMino FingoliMod 3-(hydroxymethyl)-3-nitro-1-(4-octylphenyl)-Ben

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)acetamide diethyl 2-acetamido-2-(4-octylphenethyl)malonate Octanoyl chloride

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Preparation Products

Gilenia Suppliers

Global( 208)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Casorganics US Corp	+17326109938	sales@casorganics.com	CHINA	174	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58
Longyan Tianhua Biological Technology Co., Ltd	0086 18039857276 18039857276		CHINA	2783	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Casorganics US Corp	58
Xiamen AmoyChem Co., Ltd	58
BOC Sciences	58
SIMAGCHEM CORP	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58
Longyan Tianhua Biological Technology Co., Ltd	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58

View Lastest Price from Gilenia manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-22	Fingolimod 162359-55-9	US $50.00-126.00 / mg		99.53%	10g	TargetMol Chemicals Inc.
2023-03-27	Gilenia 162359-55-9	US $10.00 / KG	1KG	99%	500MT/month	XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
2021-07-13	Gilenia 162359-55-9	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

Fingolimod
162359-55-9
US $50.00-126.00 / mg
99.53%
TargetMol Chemicals Inc.

Gilenia
162359-55-9
US $10.00 / KG
99%
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD

Gilenia
162359-55-9
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Gilenia Spectrum

Gilenia(162359-55-9)¹HNMR

162359-55-9(Gilenia)Related Search:

Fingolimod EP Impurity D Fingolimod Palmitate Amide Fingolimod Impurity 4 Benzene, 1-(2-iodoethyl)-4-octyl- Fingolimod-d4

2-DiMethylaMino FingoliMod FTY720-d4 Hydrochloride diethyl 2-acetamido-2-(4-octylphenethyl)malonate 2-(4-OCTYLPHENYL)ETHANOL Fingolimod

Fingolimod 2-Phenethyl Analog 2-NitrodeaMino FingoliMod 2-(Acetylamino)-2-[2-(4-octylphenyl)-2-oxoethyl]-propanedioic acid 1,3-diethyl ester N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)acetamide DIMETHYL 2-(HYDROXYIMINO)MALONATE

Fingolimod 3-Phenethyl Analog Fingolimod Impurity 42 Fingolimod hydrochloride

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2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol Fingolimod(FTY720) Gilenia Fingolimod 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propandiol FingoliMod Base fenogliMod 1,3-Propanediol,2-aMino-2-[2-(4-octylphenyl)ethyl]- Fingolise FingoliMod-D4 Gilenia, Fingolimod Gilenya(Fingolise) 2-amino-2-(4-octylphenethyl)propane-1,3-diol fingolimo Gilenia USP/EP/BP FingolimodQ: What is Fingolimod Q: What is the CAS Number of Fingolimod Q: What is the storage condition of Fingolimod Q: What are the applications of Fingolimod Fingolimod (FTY720 free base) Fingomod Fingolimod, 10 mM in DMSO Fingolimod - Bio-X ? 2-Amino-2-(4-octylphenethyl)-propan-1,3-diol 162359-55-9 pharmaceutical intermediate API