ChemicalBook >> CAS DataBase List >>LX-1606 Hippurate
LX-1606 Hippurate
- CAS No.
- 1033805-22-9
- Chemical Name:
- LX-1606 Hippurate
- Synonyms
- Telotristat ethyl;LX-1032;LX 1606;Telotrista;LX-1606 Hippurate;Ethyl Telotristat;LX 1606 (Telotristat);2H7]-Telotristat ethyl;TELOTRISTAT ETHYL (LX1606);LX1606 (Telotristat ethyl)
- CBNumber:
- CB92516023
- Molecular Formula:
- C27H26ClF3N6O3
- Molecular Weight:
- 574.98
- MDL Number:
- MFCD18251583
- MOL File:
- 1033805-22-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 05:34:22
| Melting point | 80-82°C |
|---|---|
| Boiling point | 704.7±70.0 °C(Predicted) |
| Density | 1.42 |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 6.72±0.33(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChIKey | MDSQOJYHHZBZKA-GBXCKJPGSA-N |
| SMILES | C(OCC)(=O)[C@H](CC1=CC=C(C2C=C(O[C@H](C3=CC=C(Cl)C=C3N3C=CC(C)=N3)C(F)(F)F)N=C(N)N=2)C=C1)N |
| FDA UNII | 8G388563M7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
LX-1606 Hippurate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 466930 | Telotristat Ethyl | 1033805-22-9 | 5mg | $382 | 2026-06-03 | Buy |
| Usbiological | 466930 | Telotristat Ethyl | 1033805-22-9 | 10mg | $496 | 2026-06-03 | Buy |
| Usbiological | 466930 | Telotristat Ethyl | 1033805-22-9 | 25mg | $779 | 2026-06-03 | Buy |
| TRC | TRC-T017098-5MG | Telotristat Ethyl | 1033805-22-9 | 5mg | $131 | 2026-06-03 | Buy |
| TRC | TRC-T017098-50MG | Telotristat Ethyl | 1033805-22-9 | 50mg | $279 | 2026-06-03 | Buy |
LX-1606 Hippurate Chemical Properties, Uses, Production
Uses
Telotristat Ethyl can be used in biological study of serotonin biosynthesis as a predictive marker of serotonin pharmacodynamics and disease-induced dysregulation.
in vivo
Telotristat ethyl (15, 50, 150, 300 mg/kg, po, qd) reduces serotonin content in the periphery, but not in the brain of the mice. Telotristat ethyl (200 mg/kg po, qd) prevents the increase in blood neutrophil counts that is observed after TNBS challenge, provides significant protection in a mouse model of inflammatory bowel disease. Telotristat ethyl (200 mg/kg po, qd) protects the mouse IBD model confirmed by histopathology evaluation[1]. Telotristat ethyl (15, 50, 150, 300 mg/kg) depletes 5-HT from the jejunum but not the brain. But Telotristat ethyl (200 mg/kg, p.o.) does not deplete enteric neuronal serotonin (5-HT), or alter constitutive gastrointestinal motility in mice. Telotristat ethyl (200 mg/kg) alleviates the severity of trinitrobenzene sulfonic acid (TNBS)-induced colitis[2].
LX-1606 Hippurate Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 117)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4593 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2915 | 55 | |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Anhui nuoquan pharmaceutical co. LTD | 15705561919 | chunli.yi@nuozhanchem.com | China | 90 | 55 |
| NCE Biomedical Co.,Ltd. | 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 | China | 1490 | 55 | |
| China Kouting Group Limited | +86 (21) 5811-6473 5811-6475 | sales@koutingchina.com | China | 494 | 60 |
| shanghai cooperpharm co.,LTD . | +86-021-58975553 | sales@cooperpharm.com | China | 1210 | 56 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| CEG Chemical Science&Technology Co., Ltd. | Mobile:13665161512 | China | 1784 | 58 | |
| Taizhou Tongxin Bio-Tech Co., Ltd | 0523-86818997 18652728585 | sales@allyrise.com | China | 2993 | 60 |
1033805-22-9 (LX-1606 Hippurate) Related Search:
(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat
4-[2-Amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-L-phenylalanine ethyl ester N-benzoylglycine salt
(S)-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)-2-(tert-butoxycarbonyl)propanoic acid
(S)-ethyl 3-(4-(2-aMino-6-((R)-1-(4-chloro-2-(3-Methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyriMidin-4-yl)phenyl)-2-(tert-butoxycarbonylaMino)propanoate
(R)-2-(4-(2-Amino-6-(1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)acetic acid
1of2
LX-1606 Hippurate
LX 1606
LX 1606 (Telotristat)
ethyl (2S)-2-amino-3-[4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl]phenyl]propanoate
Telotristat Impurity 1（Ethyl Telotristat）
TELOTRISTAT ETHYL;LX1606;LX-1606
L-Phenylalanine, 4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyriMidinyl]-, ethyl ester, LX-1606
(S)-ethyl 2-aMino-3-(4-(2-aMino-6-((R)-1-(4-chloro-2-(3-Methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyriMidin-4-yl)phenyl)propanoate 2-benzaMidoacetate
LX1606(1033805-22-9) HIPPURATE
(2S)-2-Amino-3-[4-[2-amino-6-[[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethyl]oxy]pyrimidin-4-yl]phenyl]propionic acid ethyl ester
LX-1032
(S)-2-amino-3-[4-(2-amino-6-{R-1-[4-chloro-2-(3-methyl-pyrazol-1-yl)-phenyl]-2,2,2-trifluoro-ethoxy}-pyrimidin-4-yl)-phenyl]-propionic acid ethyl ester
Telotrista
1033805-22-9 LX-1606 Hippurate
ethyl (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate
(S)-Ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-t
(S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate
Ethyl Telotristat
L-Phenylalanine, 4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-, ethyl ester
TELOTRISTAT ETHYL (LX1606)
LX1606 (Telotristat ethyl)
13C3,2H4]-Telotristat ethyl
2H7]-Telotristat ethyl
Telotristat ethyl, 10 mM in DMSO
Telotristat ethyl (LX 1606 ethyl )
Telotristat ethyl
4-[2-Amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-L-phenylalanine ethyl ester (ACI)
1033805-22-9
C27H26ClF3N6O3
