ChemicalBook >> CAS DataBase List >>2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide structure

CAS No.: 1083326-46-8

Chemical Name:: 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide

Synonyms: 1-(2-Amino-2-oxoethyl)-1H-pyrazole-4-boronic Acid Pinacol Ester;(1-(2-AMINO-2-OXOETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER;2-[4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetaMide;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetamide;2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]acetamide;1H-Pyrazole-1-acetaMide, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide;2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide 95%

CBNumber:: CB92520150

Molecular Formula:: C11H18BN3O3

Molecular Weight:: 251.09

MDL Number:: MFCD16660236

MOL File:: 1083326-46-8.mol

MSDS File:: SDS

Last updated:2026-05-28 05:36:46

Request For Quotation

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide Properties

Boiling point	440.8±25.0 °C(Predicted)
Density	1.21±0.1 g/cm3(Predicted)
storage temp.	2-8°C
pka	15+-.0.40(Predicted)
Appearance	White to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H335-H319-H302
Precautionary statements	P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HS Code	2933199090

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	161064	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetamide Asreported	1083326-46-8	1g	$496	2026-06-03	Buy
Matrix Scientific	306392	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide	1083326-46-8	250.00mg	$50	2026-05-19	Buy
Matrix Scientific	306392	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide	1083326-46-8	1.00g	$99	2026-05-19	Buy
Matrix Scientific	306392	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide	1083326-46-8	5.00g	$191	2026-05-19	Buy
aablocks	AA0083LX	1H-Pyrazole-1-acetamide, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 95%	1083326-46-8	250mg	$32	2026-05-28	Buy

Product number	Packaging	Price	Buy
161064	1g	$496	Buy
306392	250.00mg	$50	Buy
306392	1.00g	$99	Buy
306392	5.00g	$191	Buy
AA0083LX	250mg	$32	Buy

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide Chemical Properties, Uses, Production

Uses

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetamide, can be used in the preparation of pharmaceutical and biologically active compounds, including inhibitors and therapeutic agents.

Synthesis

269410-08-4

683-57-8

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide

1083326-46-8

Step 1: 4-Pyrazoleboronic acid pinacol ester (200 mg, 1.03 mmol), 2-bromoacetamide (213 mg, 1.54 mmol) and cesium carbonate (1.27 g, 3.92 mmol) were dissolved in acetonitrile (5.0 mL), and the reaction was stirred for 3 hours at 90°C. After the reaction was completed, it was cooled to room temperature, the reaction mixture was diluted with water and extracted twice with ethyl acetate. The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated in vacuum to afford pinacol ester of 1-acetamido-4-boronic acid (174 mg, 67% yield) as a white solid, which could be used in the next reaction without further purification.1H-NMR (400 MHz, CDCl3): δ 7.89 (s, 1H), 7.76 (s, 1H), 6.21 and 5.41 ( brs, 2H), 4.83 (s, 2H), 1.32 (s, 12H).

References

[1] Patent: WO2015/156601, 2015, A1. Location in patent: Page/Page column 51; 52
[2] Patent: WO2010/75270, 2010, A1. Location in patent: Page/Page column 170
[3] Patent: WO2015/95128, 2015, A1. Location in patent: Paragraph 0222; 0223
[4] Patent: EP3042907, 2016, A1. Location in patent: Paragraph 0286; 0287
[5] Patent: WO2008/154241, 2008, A1. Location in patent: Page/Page column 160

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide Preparation Products And Raw materials

Raw materials

4-Pyrazoleboronic acid pinacol ester 2-Bromoacetamide Cesium carbonate Acetonitrile

Preparation Products

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide Suppliers

Global Suppliers ( 70)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Syntechem Co.,Ltd		info@syntechem.com	China	12973	57
Wuhan TCASChem Technology Co., Ltd.	027-86697669 13986148687	sales@tcaschem.com	China	3997	55
Shanghai Topbiochem Technology Co., Ltd	+86-21-60341587	sales@topbiochem.com	China	6166	58
9ding chemical ( Shanghai) Limited	4009209199	sales@9dingchem.com	China	18201	56
SynAsst Chemical.	021-60343070		China	12731	55

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Capot Chemical Co., Ltd	66
Pure Chemistry Scientific Inc.	62
Adamas Reagent, Ltd.	59
Shanghai Hanhong Scientific Co.,Ltd.	64
Syntechem Co.,Ltd	57
Wuhan TCASChem Technology Co., Ltd.	55
Shanghai Topbiochem Technology Co., Ltd	58
9ding chemical ( Shanghai) Limited	56
SynAsst Chemical.	55

View Latest Price from 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-25	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide 1083326-46-8	$1.00	1kg	98%	1000kg	Henan Aochuang Chemical Co.,Ltd.
2021-07-13	2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide 1083326-46-8	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10	2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide 1083326-46-8	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide
1083326-46-8
$1.00
98%
Henan Aochuang Chemical Co.,Ltd.

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide
1083326-46-8
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide
1083326-46-8
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide Spectrum

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide(1083326-46-8)¹HNMR

1083326-46-8 (2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide) Related Search:

1-(difluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole N-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetamide N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-Pyrazole-1-acetamide 4-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetic acid B-[1-(2-amino-2-oxoethyl)-1H-pyrazol-4-yl]boronic acid

1H-Pyrazole-1-acetaMide, α,α-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-

1of2

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetamide 2-[4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetaMide 1H-Pyrazole-1-acetaMide, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- (1-(2-AMINO-2-OXOETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]acetamide 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide 95% 1-(2-Amino-2-oxoethyl)-1H-pyrazole-4-boronic Acid Pinacol Ester 1083326-46-8 C11H18BN3O3