Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Bromo-4-(tert-butyl)pyridine

2-Bromo-4-(tert-butyl)pyridine

2-Bromo-4-(tert-butyl)pyridine Structure
2-Bromo-4-(tert-butyl)pyridine structure
CAS No.
50488-34-1
Chemical Name:
2-Bromo-4-(tert-butyl)pyridine
Synonyms
2-Bromo-4-(tert-butyl)pyridine;Pyridine, 2-bromo-4-(1,1-dimethylethyl)-
CBNumber:
CB92559778
Molecular Formula:
C9H12BrN
Molecular Weight:
214.1
MDL Number:
MFCD11223221
MOL File:
50488-34-1.mol
MSDS File:
SDS
Last updated:2026-05-28 05:50:46
Request For Quotation

2-Bromo-4-(tert-butyl)pyridine Properties

Boiling point 243.6±20.0 °C(Predicted)
Density 1.293±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 1.50±0.10(Predicted)
form liquid
color Colourless to light yellow
InChI InChI=1S/C9H12BrN/c1-9(2,3)7-4-5-11-8(10)6-7/h4-6H,1-3H3
InChIKey JOACEYFXFYWUIK-UHFFFAOYSA-N
SMILES C1(Br)=NC=CC(C(C)(C)C)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2933399990

2-Bromo-4-(tert-butyl)pyridine price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR40352 2-Bromo-4-(tert-butyl)pyridine 97% 50488-34-1 250mg $36 2026-06-04 Buy
Apolloscientific OR40352 2-Bromo-4-(tert-butyl)pyridine 97% 50488-34-1 1g $107 2026-06-04 Buy
Activate Scientific AS111042 2-Bromo-4-(tert-butyl)pyridine 97% 50488-34-1 1g $48 2026-06-04 Buy
Activate Scientific AS111042 2-Bromo-4-(tert-butyl)pyridine 97% 50488-34-1 5g $159 2026-06-04 Buy
Activate Scientific AS111042 2-Bromo-4-(tert-butyl)pyridine 97% 50488-34-1 25g $470 2026-06-04 Buy
Product number Packaging Price Buy
OR40352 250mg $36 Buy
OR40352 1g $107 Buy
AS111042 1g $48 Buy
AS111042 5g $159 Buy
AS111042 25g $470 Buy

2-Bromo-4-(tert-butyl)pyridine Chemical Properties, Uses, Production

Synthesis

4-TERT-BUTYLPYRIDINE

3978-81-2

2-Bromo-4-(tert-butyl)pyridine

50488-34-1

A heptane (200 mL) solution of 2-(dimethylamino)ethanol (4.79 mL, 47.8 mmol) was stirred in an ice bath under nitrogen protection. A hexane solution of butyl lithium (38.2 mL, 96 mmol) was slowly added via syringe and stirring was continued at low temperature for 30 minutes. Subsequently, 4-tert-butylpyridine (7.0 mL, 47.8 mmol) was slowly added via syringe and the reaction mixture was stirred at low temperature for 1 h to obtain an orange colored solution. The solution was transferred to an iPrOH/CO2 bath for cooling and a pre-cooled solution (ice-bath cooled) of fully bromomethane (19.02 g, 57.3 mmol) dissolved in heptane (200 mL) was added slowly via cannula. The brown, non-homogeneous reaction mixture formed was stirred at low temperature for 1 h, followed by slow warming to room temperature and stirring overnight. After completion of the reaction, the mixture was again cooled in an ice bath and quenched by careful addition of water. The mixture was extracted twice with ether, the organic phases were combined and washed with brine, dried over anhydrous sodium sulfate, concentrated under reduced pressure and the residue was adsorbed onto diatomaceous earth. Finally, the separation was carried out by column chromatography on a 300 g silica gel column using 10-20% EtOAc/heptane as eluent. A brown grade (10% EtOAc/heptane) with an Rf value of about 0.3 was collected to give 2.90 g of a brown oily product containing 2-bromo-4-tert-butylpyridine in 28% yield.

References

[1] Tetrahedron Letters, 2010, vol. 51, # 50, p. 6622 - 6625
[2] Journal of Organic Chemistry, 1983, vol. 48, # 22, p. 4156 - 4158
[3] Chemical Communications, 2009, # 41, p. 6270 - 6272
[4] Patent: US2011/230462, 2011, A1
[5] Patent: US9219237, 2015, B1

2-Bromo-4-(tert-butyl)pyridine Preparation Products And Raw materials

Raw materials

4-tert-butyl-2-chloropyridine 4-tert-Butylpyridine 1-oxide 4-tert-Butylpyridine Heptane n-Butyllithium
Carbon tetrabromide Hexane

1of2

Preparation Products

2-Bromo-4-(tert-butyl)pyridine Suppliers

Global Suppliers ( 103)
Supplier Tel Email Country ProdList Advantage
Xi'an CSOAR Pharmaceutical Co.,Ltd 029-68065295 18592059708 201997953@QQ.COM China 46 58
Established by Hangzhou Boman Biochem Tech Co., Ltd 13588048971 sales@bomanbiochem.com China 491 58
Henan Weituxi Chemical Technology Co., Ltd. 0371-63284658 18135795563 3905209149@qq.com China 9702 58
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7881 64
Springchem New Material Technology Co.,Limited +86-021-62885108 info@spring-chem.com China 2068 57
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 3014 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Supplier Advantage
Xi'an CSOAR Pharmaceutical Co.,Ltd 58
Established by Hangzhou Boman Biochem Tech Co., Ltd 58
Henan Weituxi Chemical Technology Co., Ltd. 58
Beijing Ouhe Technology Co., Ltd 60
Tetranov Biopharm 64
Springchem New Material Technology Co.,Limited 57
Shanghai Topbiochem Technology Co., Ltd 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
Cochemical Ltd. 58
Bide Pharmatech Ltd. 60

View Latest Price from 2-Bromo-4-(tert-butyl)pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-4-(tert-butyl)pyridine pictures 2026-06-30 2-Bromo-4-(tert-butyl)pyridine
50488-34-1
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd

2-Bromo-4-(tert-butyl)pyridine Spectrum

2-Bromo-4-(tert-butyl)pyridine(50488-34-1)1HNMR

50488-34-1 (2-Bromo-4-(tert-butyl)pyridine) Related Search:

Pyridine, 2,6-dibromo-4-(1,1-dimethylethyl)- 2-bromo-4-isopropylpyridine 2-Bromo-4-ethylpyridine 2-Bromo-4-(tert-butyl-d9)-pyridine 4-Pyridineacetonitrile, 2-bromo-α,α-dimethyl-
Pyridine, 2-bromo-4-(1,1-dimethylethyl)-6-fluoro-

1of2

2-Bromo-4-(tert-butyl)pyridine Pyridine, 2-bromo-4-(1,1-dimethylethyl)- 50488-34-1