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Decamethylcyclopentasiloxane

CAS No.
541-02-6
Chemical Name:
Decamethylcyclopentasiloxane
Synonyms
Cyclopentasiloxane, decamethyl-;CYCLOPENTASILOXANE;D5;Cyclomethicone 5;DecamethyL;DECAMETHYLCYCLOPENTASILOXAN;2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane;D5 Cyclomethicone;Dimethylsiloxane pentamer;Decamethylcylopentasiloxane
CBNumber:
CB9256200
Molecular Formula:
C10H30O5Si5
Molecular Weight:
370.77
MDL Number:
MFCD00046966
MOL File:
541-02-6.mol
MSDS File:
SDS
Last updated:2026-04-10 10:27:33
Product description Number Pack Size Price
Decamethylcyclopentasiloxane analytical standard 43217 250mg $106
Cyclomethicone 5 United States Pharmacopeia (USP) Reference Standard 1154809 200mg $470
Decamethylcyclopentasiloxane >99.0%(GC) D1890 25mL $25
Decamethylcyclopentasiloxane >99.0%(GC) D1890 100mL $56
D5 Cyclomethicone Pharmaceutical Secondary Standard; Certified Reference Material PHR1566 500mg $122
More product size

Decamethylcyclopentasiloxane Properties

Melting point -44°C
Boiling point 90 °C/10 mmHg (lit.)
Density 0.958 g/mL at 25 °C (lit.)
vapor pressure 33.2Pa at 25℃
refractive index n20/D 1.396(lit.)
Flash point 162 °F
storage temp. 2-8°C
solubility <0.0001g/l (calculated)
form Liquid
Specific Gravity 0.959
color Colorless
explosive limit 0.52-7%(V)
Water Solubility Immiscible with water.
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
Merck 14,2848
BRN 1800166
Henry's Law Constant 2.8×10-7 mol/(m3Pa) at 25℃, Xu and Kropscott (2014)
Dielectric constant 2.5(20℃)
Stability Stable. Incompatible with strong oxidizing agents.
Major Application cleaning products
cosmetics
environmental
food and beverages
personal care
Cosmetics Ingredients Functions SKIN CONDITIONING - EMOLLIENT
SOLVENT
HAIR CONDITIONING
SKIN CONDITIONING
Cosmetic Ingredient Review (CIR) Decamethylcyclopentasiloxane (541-02-6)
InChI 1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3
InChIKey XMSXQFUHVRWGNA-UHFFFAOYSA-N
SMILES C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1
LogP 8.07 at 24.6℃
Surface tension 18.29 mN/m at 297.15K
Substances of Very High Concern (SVHC) Candidate List Decamethylcyclopentasiloxane (541-02-6)
CAS DataBase Reference 541-02-6(CAS DataBase Reference)
EWG's Food Scores 3
FDA UNII 0THT5PCI0R
NIST Chemistry Reference Decamethylcyclopentasiloxane(541-02-6)
EPA Substance Registry System Decamethylcyclopentasiloxane (541-02-6)
UNSPSC Code 77101502
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H227-H320-H413
Precautionary statements  P210-P264-P280-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501-P210e-P280a-P370+P378a-P501a
Hazard Codes  Xi
Risk Statements  36/37/38-53
Safety Statements  23-24/25-36-26
RIDADR  NA 1993 / PGIII
WGK Germany  2
RTECS  GY5945200
TSCA  TSCA listed
HS Code  29310095
Storage Class 10 - Combustible liquids
Hazardous Substances Data 541-02-6(Hazardous Substances Data)
Toxicity LD50 oral in rat: > 24134mg/kg
NFPA 704
2
0 0

Decamethylcyclopentasiloxane price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 43217 Decamethylcyclopentasiloxane analytical standard 541-02-6 250mg $106 2026-03-19 Buy
Sigma-Aldrich 1154809 Cyclomethicone 5 United States Pharmacopeia (USP) Reference Standard 541-02-6 200mg $470 2026-03-19 Buy
TCI Chemical D1890 Decamethylcyclopentasiloxane >99.0%(GC) 541-02-6 25mL $25 2026-03-19 Buy
TCI Chemical D1890 Decamethylcyclopentasiloxane >99.0%(GC) 541-02-6 100mL $56 2026-03-19 Buy
Sigma-Aldrich PHR1566 D5 Cyclomethicone Pharmaceutical Secondary Standard; Certified Reference Material 541-02-6 500mg $122 2026-03-19 Buy
Product number Packaging Price Buy
43217 250mg $106 Buy
1154809 200mg $470 Buy
D1890 25mL $25 Buy
D1890 100mL $56 Buy
PHR1566 500mg $122 Buy

Decamethylcyclopentasiloxane Chemical Properties,Uses,Production

Chemical Properties

liquid

Uses

A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products. Used in dermal exposure and inhalation toxicity study.

Uses

Intermediate in the manufacture of high mol wt siloxane polymers. Carrier ingredient in personal care products; dry cleaning solvent.

Uses

cyclopentasiloxane is incorporated into a formulation for its emollient and solvent activity.

Uses

Octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.

Definition

ChEBI: Decamethylcyclopentasiloxane is an organosilicon compound.

General Description

D5 Cyclomethicone is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom. It is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Flammability and Explosibility

Non flammable

Toxics Screening Level

The initial threshold screening level (ITSL) for decamethylcyclopentasiloxane is 200 μg/m3, with annual averaging time.

75-78-5
541-05-9
556-67-2
541-02-6
Synthesis of Decamethylcyclopentasiloxane from Dichlorodimethylsilane

Decamethylcyclopentasiloxane Preparation Products And Raw materials

Global( 429)Suppliers
Supplier Tel Email Country ProdList Advantage
QINGDAO KAIENSI INTERNATIONAL TRADE CO.,LTD.
+86-0532-8699-9256 +8615254267723 kaley@cnfdevelop.com China 1410 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Yanxi Chemical Co., Ltd.
+8618531123677 faithe@yan-xi.com China 5853 58
Wuhan Fortuna Chemical Co., Ltd
+86-27-59207850 info@fortunachem.com China 5972 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5235 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850 hbjbtech@163.com China 1000 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3692 58
Hebei Longbang Technology Co., LTD
+86-18633929156 admin@hblongbang.com China 972 58
Shandong Deshang Chemical Co., Ltd.
+86-0531-8875-2665 +8613153039501 info@deshangchem.com China 661 58

View Lastest Price from Decamethylcyclopentasiloxane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Decamethylcyclopentasiloxane pictures 2026-04-17 Decamethylcyclopentasiloxane
541-02-6
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Decamethylcyclopentasiloxane pictures 2026-03-20 Decamethylcyclopentasiloxane
541-02-6
US $1.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
Decamethylcyclopentasiloxane pictures 2025-09-25 Decamethylcyclopentasiloxane
541-02-6
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane cyclicdimethylsiloxanepentamer D3770 Decamethylcylopentasiloxane siliconsf1202 unioncarbide7158siliconefluid vs7158 CYCLIC PENTAMER-D5 DECAMETHYLCYCLOPENTASILOXANE Decamethylcyclopentasiloxane (cyclic monomer)Cyclic Pentamer-D5 VOLASIL(TM) 245 CYCLOPENTASILOXANE,DECANE Cyclopentasiloxane,2,2,4,4,6,6,8,8,10,10-decaMethyl- D5 Cyclomethicone cyclomethicone dc 245 Decamethylcyclopentasiloxane (cyclic monomer) DECAMETHYLCYCLOPENTASILOXANE FOR SYNTHES Decamethylclopentasiloxane Ddecamethylcyclopentasiloxane D5 DECAMETHYLCYCLOPENTASILOXANE DC 5225C Formulation Aid DecamethyL opentasiL Decamethylcyclopentasiloxane 541-02-6 Cyclopentasiloxane 4-Aminobiphenyl-2&rsquo 2,3,4-Trihydroxybenzophenone-2&rsquo 2-Nitrobiphenyl-2&rsquo 8&rsquo -Eudesmol-7,7,8a,8&rsquo -E)-Daptomycin -epi Vinorelbine Bitartrate 4-Amino-3-methylbiphenyl-2&rsquo 4-Nitrobiphenyl-2&rsquo N-Fmoc-4&rsquo -tetra-O-acetyl-3-O-benzoyl STn Epitope Methyl Ester 2-Aminobiphenyl-2&rsquo :4,5]imidazo[1,2-a]pyrimidinium Chloride 8,9,10,11-Tetrahydro-2,7-dimethyl-9-hydroxy-quinoxalo[7&rsquo Decaαthyl-pentasil-pentoxan Dekamethylcyklopentasiloxan dimethylsiloxanepentamer dowcorning345 dowcorning345fluid kf995 nucsiliconevs7158 sf1202 Pentacyclomethicone 1,1,3,3,5,5,7,7,9,9-Decamethyl-1,3,5,7,9-pentasila-2,4,6,8,10-pentaoxacyclodecane 2,2,4,4,6,6,8,8,10,10-Decamethyl-2,4,6,8,10-pentasila-1,3,5,7,9-pentaoxacyclodecane 2,2,4,4,6,6,8,8,10,10-Decamethylcyclodecanepentasiloxane 2,2,4,4,6,6,8,8,10,10-Decamethylcyclodecapentasiloxane Decamethylcyclodecanepentasiloxane 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane Decamethylcyclopentasiloxane, 96+% Cyclomethicone 5 (200 mg) 2,2,4,4,6,6,8,8,10,10-DecaMethylcyclopentasiloxane Botanisil CP 33 Cyclo-decaMethylpentasiloxane