(3-aMino-5-Methoxyphenyl)Methanol
- CAS No.
- 1261566-52-2
- Chemical Name:
- (3-aMino-5-Methoxyphenyl)Methanol
- Synonyms
- 3-Amino-5-methoxybenzenemethanol;(3-aMino-5-Methoxyphenyl)Methanol;Benzenemethanol, 3-amino-5-methoxy-
- CBNumber:
- CB92582374
- Molecular Formula:
- C8H11NO2
- Molecular Weight:
- 153.18
- MDL Number:
- MFCD18389739
- MOL File:
- 1261566-52-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P280 |
(3-aMino-5-Methoxyphenyl)Methanol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS115655 | (3-Amino-5-methoxyphenyl)methanol 95% | 1261566-52-2 | 1g | $582 | 2026-06-04 | Buy |
| Matrix Scientific | 305505 | (3-Amino-5-methoxyphenyl)methanol | 1261566-52-2 | 100.00mg | $56 | 2026-05-19 | Buy |
| Matrix Scientific | 305505 | (3-Amino-5-methoxyphenyl)methanol | 1261566-52-2 | 250.00mg | $91 | 2026-05-19 | Buy |
| Matrix Scientific | 305505 | (3-Amino-5-methoxyphenyl)methanol | 1261566-52-2 | 1.00g | $247 | 2026-05-19 | Buy |
| ACHEMBLOCK | Y222224 | (3-Amino-5-methoxyphenyl)methanol 95.00% | 1261566-52-2 | 1G | $300 | 2026-05-27 | Buy |
(3-aMino-5-Methoxyphenyl)Methanol Chemical Properties, Uses, Production
Synthesis
74165-74-5
1261566-52-2
General procedure for the synthesis of (3-amino-5-methoxyphenyl)methanol from 3-amino-5-methoxybenzoic acid: lithium aluminum hydride (LiAlH4, 2.3 g, 0.06 mol) was added batchwise to an anhydrous tetrahydrofuran (THF, 100 mL) solution of 3-amino-5-methoxybenzoic acid (5 g, 0.03 mol) at 0 °C. The reaction mixture was stirred at 0 °C overnight and subsequently cooled to 0 °C and the reaction was quenched by slow addition of aqueous potassium hydroxide (20%, 5 mL) followed by addition of ethyl acetate (50 mL). The mixture was filtered through a diatomaceous earth pad and washed with ethyl acetate. The filtrate was dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. The crude product was purified by fast chromatography (eluent ratio tapered from 60:40 to 40:60, hexane:ethyl acetate) to afford (3-amino-5-methoxyphenyl)methanol (13) as a light yellow solid (2.75 g, 60% yield).1H NMR (400 MHz, CDCl3): δ 6.38 (s, 1H), 6.34 (s, 1H), and 6.31 (s, 1H), 4.39 (s, 2H), 3.79 (s, 3H), 3.77 (s, 2H).13C NMR (100MHz, CDCl3): δ160.61,147.49,143.13,105.90,102.04,99.87,64.98,54.78.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 21, p. 6621 - 6627
[2] Patent: WO2011/135376, 2011, A1
[3] Journal of Medicinal Chemistry, 2018, vol. 61, # 18, p. 8390 - 8401
(3-aMino-5-Methoxyphenyl)Methanol Preparation Products And Raw materials
Raw materials
Preparation Products
(3-aMino-5-Methoxyphenyl)Methanol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 0512-0512-52358471 17715136450 | sales@shiyabiopharm.com | China | 9814 | 58 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Aikon International Limited | 025-66113011 19370895928 | qzhang@aikonchem.com | China | 15390 | 58 |
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| Tianjin Nuokang Pharmaceutical Technology Co., Ltd. | 022-23989838 13810451150 | 44766350@qq.com | China | 2727 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Lingyuan Bebiansen Biological Technology Co., Ltd | 18642120371 | 2837458851@qq.com | China | 7961 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39796 | 58 |
