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1-NBD-decanoyl-2-decanoyl-sn-Glycerol

1-NBD-decanoyl-2-decanoyl-sn-Glycerol Structure
1-NBD-decanoyl-2-decanoyl-sn-Glycerol structure
CAS No.
2309189-98-6
Chemical Name:
1-NBD-decanoyl-2-decanoyl-sn-Glycerol
Synonyms
1-NBD-1,2-bis(O-decanoyl-sn-glycerol);1-NBD-decanoyl-2-decanoyl-sn-Glycerol
CBNumber:
CB92589964
Molecular Formula:
C29H46N4O8
Molecular Weight:
578.69754
MDL Number:
MOL File:
2309189-98-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:57:03
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1-NBD-decanoyl-2-decanoyl-sn-Glycerol Properties

solubility DMF: 10 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

1-NBD-decanoyl-2-decanoyl-sn-Glycerol price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 9000341 1-NBD-decanoyl-2-decanoyl-sn-Glycerol ≥98% 2309189-98-6 500μg $132 2026-04-30 Buy
Cayman Chemical 9000341 1-NBD-decanoyl-2-decanoyl-sn-Glycerol ≥98% 2309189-98-6 1mg $251 2026-04-30 Buy
Cayman Chemical 9000341 1-NBD-decanoyl-2-decanoyl-sn-Glycerol ≥98% 2309189-98-6 5mg $1048 2026-04-30 Buy
Biosynth JSD18998 1-NBD-decanoyl-2-decanoyl-sn-glycerol 2309189-98-6 5mg $1392.1 2026-06-04 Buy
Biosynth JSD18998 1-NBD-decanoyl-2-decanoyl-sn-glycerol 2309189-98-6 10mg $2227.4 2026-06-04 Buy
Product number Packaging Price Buy
9000341 500μg $132 Buy
9000341 1mg $251 Buy
9000341 5mg $1048 Buy
JSD18998 5mg $1392.1 Buy
JSD18998 10mg $2227.4 Buy

1-NBD-decanoyl-2-decanoyl-sn-Glycerol Chemical Properties, Uses, Production

Description

Diacylglycerols (DAG) are produced by the hydrolysis of membrane phospholipids. They act as lipid second messengers, activating PKC and regulating cell growth and apoptosis. They also serve as substrates for DAG kinases for the production of phosphatidic acid, another important lipid messenger. 1-NBD-decanoyl-2-decanoyl-sn-glycerol has the fluorophore nitrobenzoxadiazole (NBD) attached to the ω-end of the terminal decanoyl chain of the model diacylglycerol (DAG), 1,2-didecanoyl-sn-glycerol. 1-NBD-decanoyl-2-decanoyl-sn-glycerol is likely to have excitation/emission maxima of approximately 470/541 nm, respectively, based on the maxima of various NBD-labeled phospholipids.1 Fluorescently tagged lipids have been used to study their interactions with proteins, their utilization by cells and liposomes, and for the development of assays for lipid metabolism.2,3,4,5,6

Uses

1-NBD-decanoyl-2-decanoyl-sn-glycerol is a diacylglycerol (DAG) derivative, which is labeled with a fluorescent group NBD. 1-NBD-decanoyl-2-decanoyl-sn-glycerol is the substrate for diacylglycerol kinase (DGK), and can be used for quantitative detection of the DGF enzyme kinetics in vitro, and the changes in DAG and PA during cell signaling[1].

References

1. Mazères, S., Schram, V., Tocanne, J.F., et al. 7-nitrobenz-2-oxa-1,3-diazole-4-yl-labeled phospholipids in lipid membranes: Differences in fluorescence behavior Biophys J. 71(1),327-335(1996).
2. Kumagai, K., Yasuda, S., Okemoto, K., et al. CERT mediates intermembrane transfer of various molecular species of ceramides J. Biol. Chem. 280(8),6488-6495(2005).
3. Luo, M., Jones, S.M., Peters-Golden, M., et al. Nuclear localization of 5-lipoxygenase as a determinant of leukotriene B4 synthetic capacity Proc. Natl. Acad. Sci. USA 100(21),12165-12170(2003).
4. Moreno, M.J., Estronca, L.M.B.B., and Vaz, W.L.C. Translocation of phospholipids and dithionite permeability in liquid-ordered and liquid-disordered membranes Biophys. J. 91(3),873-881(2006).
5. Loidl, A., Claus, R., Deigner, H.P., et al. High-precision fluorescence assay for sphingomyelinase activity of isolated enzymes and cell lysates J. Lipid Res. 43(5),815-823(2002).
6. Tani, M., Okino, N., Mitsutake, S., et al. Specific and sensitive assay for alkaline and neutral ceramidases involving C12-NBD-ceramide J. Biochem. 125(4),746-749(1999).

1-NBD-decanoyl-2-decanoyl-sn-Glycerol Preparation Products And Raw materials

Raw materials

Preparation Products

1-NBD-decanoyl-2-decanoyl-sn-Glycerol Suppliers

Global Suppliers ( 28)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen 18818260767 2625930290@qq.com China 6966 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
SHANGHAI ZZBIO CO., LTD. 58

2309189-98-6 (1-NBD-decanoyl-2-decanoyl-sn-Glycerol) Related Search:

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1-NBD-decanoyl-2-decanoyl-sn-Glycerol 1-NBD-1,2-bis(O-decanoyl-sn-glycerol) 2309189-98-6