4-BroMo-5-fluoro-2-nitro-benzoic acid Methyl ester
- CAS No.
- 1220886-29-2
- Chemical Name:
- 4-BroMo-5-fluoro-2-nitro-benzoic acid Methyl ester
- Synonyms
- Methyl 4-broMo-5-fluoro-2-nitrobenzoate;2-nitro-4-bromo-5-fluorobenzoic acid methyl ester;4-BroMo-5-fluoro-2-nitro-benzoic acid Methyl ester;3-Bromo-2-fluoro-6-nitro-benzoic acid methyl ester;Benzoic acid, 4-bromo-5-fluoro-2-nitro-, methyl ester
- CBNumber:
- CB92629677
- Molecular Formula:
- C8H5BrFNO4
- Molecular Weight:
- 278.03
- MDL Number:
- MFCD21606583
- MOL File:
- 1220886-29-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl4-bromo-5-fluoro-2-nitrobenzoate | 4783DT | 1g | $104 |
| Methyl4-bromo-5-fluoro-2-nitrobenzoate | 4783DT | 5g | $188 |
| Methyl4-bromo-5-fluoro-2-nitrobenzoate 98% | CD12171242 | 25g | $303 |
| Methyl4-bromo-5-fluoro-2-nitrobenzoate 98% | A144083 | 10g | $306 |
| methyl4-bromo-5-fluoro-2-nitrobenzoate 95+% | CM159081 | 25g | $327 |
| More product size | |||
| Boiling point | 337.6±42.0 °C(Predicted) |
|---|---|
| Density | 1.742±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| Appearance | White to yellow Solid |
| InChI | InChI=1S/C8H5BrFNO4/c1-15-8(12)4-2-6(10)5(9)3-7(4)11(13)14/h2-3H,1H3 |
| InChIKey | HPMNCYDJGIMYKN-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC(F)=C(Br)C=C1[N+]([O-])=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H302-H319-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P |
4-BroMo-5-fluoro-2-nitro-benzoic acid Methyl ester price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 4783DT | Methyl4-bromo-5-fluoro-2-nitrobenzoate | 1220886-29-2 | 1g | $104 | 2021-12-16 | Buy |
| AK Scientific | 4783DT | Methyl4-bromo-5-fluoro-2-nitrobenzoate | 1220886-29-2 | 5g | $188 | 2021-12-16 | Buy |
| Crysdot | CD12171242 | Methyl4-bromo-5-fluoro-2-nitrobenzoate 98% | 1220886-29-2 | 25g | $303 | 2021-12-16 | Buy |
| Ambeed | A144083 | Methyl4-bromo-5-fluoro-2-nitrobenzoate 98% | 1220886-29-2 | 10g | $306 | 2021-12-16 | Buy |
| Chemenu | CM159081 | methyl4-bromo-5-fluoro-2-nitrobenzoate 95+% | 1220886-29-2 | 25g | $327 | 2021-12-16 | Buy |
4-BroMo-5-fluoro-2-nitro-benzoic acid Methyl ester Chemical Properties,Uses,Production
Synthesis
1020717-99-0
74-88-4
1220886-29-2
Potassium carbonate (5.870 g, 42.47 mmol) was slowly added to a stirred solution of 4-bromo-5-fluoro-2-nitrobenzoic acid (Ark Pharm, 5.387 g, 20.40 mmol) in N,N-dimethylformamide (DMF, 80.0 mL) at 0 °C, followed by dropwise addition of iodomethane (8.789 g, 61.92 mmol). The reaction mixture was stirred at 0 °C for 15 min and then gradually warmed up to 40 °C and maintained for 2 hours. After completion of the reaction, the mixture was filtered and concentrated. The concentrated residue was dissolved in ethyl acetate (EtOAc, 150 mL), washed sequentially with water (2 x 100 mL) and saturated brine (100 mL), and the organic phase was dried with anhydrous sodium sulfate (Na2SO4), and concentrated under reduced pressure to remove the solvent. The crude product obtained was purified by fast column chromatography on silica gel with the eluent being hexane solution of 0-50% ethyl acetate to give methyl 4-bromo-5-fluoro-2-nitrobenzoate as a light yellow oil (5.348 g, 94% yield). Liquid chromatography-mass spectrometry (LCMS) analysis: theoretically calculated value for C8H6BrFNO4 ([M+H]+): m/z = 277.9; no ionization was observed.
References
[1] Patent: US2014/200216, 2014, A1. Location in patent: Paragraph 0485; 0486
4-BroMo-5-fluoro-2-nitro-benzoic acid Methyl ester Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from 4-BroMo-5-fluoro-2-nitro-benzoic acid Methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-13 | 4-BroMo-5-fluoro-2-nitro-benzoic acid Methyl ester
1220886-29-2
|
US $1.00 / KG | 1g | 99.0% | 100kg | Career Henan Chemical Co |
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- 4-BroMo-5-fluoro-2-nitro-benzoic acid Methyl ester
1220886-29-2
- US $1.00 / KG
- 99.0%
- Career Henan Chemical Co
