ChemicalBook >> CAS DataBase List >>6-O-Benzylguanine
6-O-Benzylguanine
- CAS No.
- 19916-73-5
- Chemical Name:
- 6-O-Benzylguanine
- Synonyms
- 6-benzylguanine;O6-BENZYLGUANINE;O6-Benzylguanine ,98%;6-(benzyloxy)-7H-purin-2-aMine;O6-BenzyL;NSC 637037;6-O-BENZYLGUANINE;6-BENZYLOXY GUANINE;6-oxo -benzylguanine;4 6-Benzyloxyguanine
- CBNumber:
- CB9263934
- Molecular Formula:
- C12H11N5O
- Molecular Weight:
- 241.25
- MDL Number:
- MFCD00269931
- MOL File:
- 19916-73-5.mol
- MSDS File:
- SDS
Last updated:2025-07-15 10:39:55
| Melting point | 193(dec.) |
|---|---|
| Boiling point | 459.3±55.0 °C(Predicted) |
| Density | 1.48±0.1 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | methanol: 20 mg/mL |
| form | solid |
| pka | 7.47±0.20(Predicted) |
| color | Off-White to Light Yellow |
| InChI | InChI=1S/C12H11N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H3,13,14,15,16,17) |
| InChIKey | KRWMERLEINMZFT-UHFFFAOYSA-N |
| SMILES | N1C2C(=NC(N)=NC=2OCC2=CC=CC=C2)NC=1 |
| CAS DataBase Reference | 19916-73-5(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | O(6)-benzylguanine |
| FDA UNII | 01KC87F8FE |
| NCI Drug Dictionary | O6-benzylguanine |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
6-O-Benzylguanine price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B2292 | O6-Benzylguanine ≥98% (TLC), solid | 19916-73-5 | 50mg | $107 | 2024-03-01 | Buy |
| Alfa Aesar | H60274 | O6-Benzylguanine, 98% | 19916-73-5 | 250mg | $47.65 | 2024-03-01 | Buy |
| Cayman Chemical | 16332 | O6-Benzylguanine ≥98% | 19916-73-5 | 10mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 16332 | O6-Benzylguanine ≥98% | 19916-73-5 | 1g | $699 | 2024-03-01 | Buy |
| Cayman Chemical | 16332 | O6-Benzylguanine ≥98% | 19916-73-5 | 50mg | $56 | 2024-03-01 | Buy |
6-O-Benzylguanine Chemical Properties,Uses,Production
Chemical Properties
Light Yellow Solid
Uses
An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.
Uses
O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Biochem/physiol Actions
O6-Benzylguanine (O6BG) inhibits methylguanine methyltransferase (MGMT) by blocking the active site through benzyl group transfer. The use of O6BG with bis-chloroethylnitrosourea (BCNU) or carmustine is effective in treating solid tumors including lymphomas, melanomas and sarcoma.
6-O-Benzylguanine Preparation Products And Raw materials
Global( 445)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +86-13288715578 | sales@hbmojin.com | China | 12703 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20203 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
View Lastest Price from 6-O-Benzylguanine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-21 | 6-O-Benzylguanine
19916-73-5
|
US $0.00-0.00 / Kg/Drum | 1KG | 99%min | 1000kgs | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-07-14 | O6-Benzylguanine
19916-73-5
|
US $62.00-42.00 / mg | 98.90% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-07-07 | 6-O-Benzylguanine
19916-73-5
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd |
-
- 6-O-Benzylguanine
19916-73-5
- US $0.00-0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- O6-Benzylguanine
19916-73-5
- US $62.00-42.00 / mg
- 98.90%
- TargetMol Chemicals Inc.
-
- 6-O-Benzylguanine
19916-73-5
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
19916-73-5(6-O-Benzylguanine)Related Search:
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O(sup 6)benzylguanidine
O6-Benzylguanine ,98%
2-Amino-6-(benzyloxy)-9H-purine
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6-(benzyloxy)-7H-purin-2-aMine
6-(PhenylMethoxy)-9H-purin-2-aMine
NSC 637037
6-benzylguanine
6-oxo -benzylguanine
6-O-Benzylguanine(O6BG)
9H-Purin-2-amine,6-(phenylmethoxy)-
6-phenylmethoxy-7H-purin-2-amine
O6-BENZYLGUANINE
2-Amino-6-(benzyloxy)purine
2-amino-6-(phenylmethoxy)-9h-purine
Ganciclovir Impurity 12
6-O-BENZYLGUANINE
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6-BENZYLOXY GUANINE
4 6-Benzyloxyguanine
6-BENZYLOXY GUANINE2-AMINO-6-BENZYLOXYPURINE
O6-BenzyL
2-((2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)propane-1,3-diyl dibenzoate
"2-Amino-6-(benzyloxy)purine, 2-Amino-6-(phenylmethoxy)-9H-purine"
6-(Phenylmethoxy)-1H-purin-2-amine
O6-Benzylguanine
O6-Benzylguanine - Bio-X ?
19916-73-5
9916-73-5
Apoptosis and Cell Cycle
DNA Repair Regulators
DNA metabolism
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Alkylguanine-DNA alkyltransferase, mammalian DNA repair proteinApoptosis and Cell Cycle
DNA Repair Regulators
A to
DNA metabolism
Enzyme Inhibitors by Enzyme
Nucleotides and Nucleosides
Bases & Related Reagents
Nucleotides