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Elamipretide

Elamipretide structure

CAS No.: 736992-21-5

Chemical Name:: Elamipretide

Synonyms: MTP-131;Centanafadine;SS-31, Elamipretide;Elamipretide acetate;RX-31;SS-31);Bendavia);Elamipretide;SS-31 10mg/20mg;ELAMIPRETIDE, >99%

CBNumber:: CB92708860

Molecular Formula:: C32H49N9O5

Molecular Weight:: 639.79

MDL Number:: MFCD20133791

MOL File:: 736992-21-5.mol

Last updated:2025-09-24 16:57:48

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Elamipretide Properties

Density	1.34±0.1 g/cm3(Predicted)
solubility	Methanol (Slightly), Water (Slightly)
pka	10.10±0.25(Predicted)
form	Solid
color	White to Off-White
Sequence	H-d-Arg-dimethylTyr-Lys-Phe-NH2
Stability	Hygroscopic
InChIKey	SFVLTCAESLKEHH-WKAQUBQDSA-N
SMILES	C(N)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=C(C)C=C(O)C=C1C)NC(=O)[C@@H](CCCNC(N)=N)N
FDA UNII	87GWG91S09

Elamipretide price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
DC Chemicals	DC21695	Elamipretide(TFAsalt) >98%	736992-21-5	100mg	$950	2021-12-16	Buy
DC Chemicals	DC21695	Elamipretide(TFAsalt) >98%	736992-21-5	1g	$3800	2021-12-16	Buy

Product number	Packaging	Price	Buy
DC21695	100mg	$950	Buy
DC21695	1g	$3800	Buy

Elamipretide Chemical Properties,Uses,Production

Description

Elamipretide, also known as MTP 131, is a mitochondria-targeted peptide antioxidant. Elamipretide decreases inflammation and protect against a variety of neurological illnesses. Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice. Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells.

Uses

D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide-d5 Trifluoroacetic Acid Salt is labelled D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide (A769700) which is a mitochondrial-targeted compound that re-energizes ischemic mitochondria by interacting with cardiolipin. It is a cell-permeable antioxidant peptide.

Mechanism of action

Elamipretide can inhibit the production of pathogenic ROS (reactive oxygen species) and restore mitochondrial ATP synthesis. Currently, the most accepted mechanism for these two actions is the direct interaction between Elamipretide and cardiolipin.

Clinical Use

Barth syndrome is an ultra-rare genetic condition characterized by cardiac abnormalities leading to exercise intolerance, muscle weakness, debilitating fatigue, heart failure, recurrent infections, and delayed growth. There are currently no FDA- or EMA-approved therapies for patients with Barth syndrome. Elamipretide has an Orphan Drug, Fast Track and Rare Pediatric Designation from the FDA and Orphan Drug Designation from the EMA for treating Barth syndrome.

Side effects

Side effects of elamipretide include:
Mild redness or itching at the injection site
Headache
Dizziness

Elamipretide Preparation Products And Raw materials

Raw materials

Preparation Products

Elamipretide Suppliers

Global( 181)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Kebeilai Pharmaceutical Biotech Co., Ltd.	+86-18240866958	wangjasmine7289@gmail.com	China	1022	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618092446649	sarah@tnjone.com	China	1143	58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD	+86-15350851019; +8615350851019	admin@86-ss.com	China	999	58
Shandong Huizhihan Supply Chain Co., Ltd	+86-13363081709 +86-13363000288	3957328362@qq.com	China	300	58
American HealthyMorph LLC	+85269498027	nancyyuan133@163.com	China	169	58
Wuhan Haorong Biotechnology Co.,ltd	+8618565342920	sales@chembj.net	China	300	58
Wuhan Kejiefeng Trading Co.,Ltd	+undefined18827003015	dong19981022@gmail.com	China	178	58
Hebei Jiafan Trading Company Limited	+86-15354498258	sales01@jiafan88.com	China	180	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-17392712697	1022@dideu.com	China	3995	58
RongNa Biotechnology Co.,Ltd	+86-86-13583358881 +8618560316533	Brad@rongnabiotech.com	China	3390	58

Supplier	Advantage
Kebeilai Pharmaceutical Biotech Co., Ltd.	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD	58
Shandong Huizhihan Supply Chain Co., Ltd	58
American HealthyMorph LLC	58
Wuhan Haorong Biotechnology Co.,ltd	58
Wuhan Kejiefeng Trading Co.,Ltd	58
Hebei Jiafan Trading Company Limited	58
Shaanxi Dideu Medichem Co. Ltd	58
RongNa Biotechnology Co.,Ltd	58

Elamipretide: Indications, Mechanisms of Action and Side Effects
Elamipretide is a first-in-class mitochondrial targeted therapeutic being developed for the treatment of diseases associated w....
Jan 17，2025

What is Elamipretide used for?
Elamipretide is an aromatic-cationic tetrapeptide that readily penetrates cell membranes and transiently localizes to the inne....
May 7，2022

View Lastest Price from Elamipretide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-04	Elamipretide 736992-21-5	US $1.00 / g	1g	99%	100kg	RongNa Biotechnology Co.,Ltd
2025-10-04	Elamipretide 736992-21-5	US $0.00-0.00 / G	1G	99%	1 ton/year	Forest chemical technology
2025-10-04	SS-31 10mg/20mg 736992-21-5	US $110.00-90.00 / kit	1kit	99%	10000kits	Shenzhen Aoxi Technology Co., Ltd.

Elamipretide
736992-21-5
US $1.00 / g
99%
RongNa Biotechnology Co.,Ltd

Elamipretide
736992-21-5
US $0.00-0.00 / G
99%
Forest chemical technology

SS-31 10mg/20mg
736992-21-5
US $110.00-90.00 / kit
99%
Shenzhen Aoxi Technology Co., Ltd.

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D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide Elamipretide Centanafadine L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl- Elamipretide (TFA salt) SS-31;MTP-131;BENDAVIA Bendavia) Elamipretide (SS-31 MTP-131 ELAMIPRETIDE, >99% Elamipretide,MTP-131,RX-31,SS-31, >99% Elamipretide (MTP-131 ELAMIPRETIDE (MTP-131;RX-31;SS-31) RX-31 SS-31) SS-31, Elamipretide Elamipretide acetate Elamipretide (SS-31) acetate (S)-6-Amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide Elamipretide（HY-P0125 Elamipretide、SS-31、H2N-D-Arg-Dmt-Lys-Phe-NH2 SS-31 10mg/20mg Elamipretide (MTP-131, SS-31) Elamipretide (MTP-131) ，S9803 736992-21-5 736992-21-5