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3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER

CAS No.
403-01-0
Chemical Name:
3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
Synonyms
METHYL 3-FLUORO-4-HYDROXYBENZOATE;RARECHEM AL BF 0259;Fluoro-4-hydroxybenzoate;3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER;Benzoic acid, 3-fluoro-4-hydroxy-, methyl ester
CBNumber:
CB9281077
Molecular Formula:
C8H7FO3
Molecular Weight:
170.14
MDL Number:
MFCD00215838
MOL File:
403-01-0.mol
MSDS File:
SDS
Last updated:2026-05-28 06:22:43
Product description Number Pack Size Price
3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 276114 1g $360
3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 276114 2g $489
3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 276114 5g $729
3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 276114 10g $1083
3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 276114 25g $1593
More product size

3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Properties

Melting point 91-93℃
Boiling point 259.9±25.0℃ (760 Torr)
Density 1.309±0.06 g/cm3 (20 ºC 760 Torr)
Flash point 111.0±23.2℃
storage temp. Sealed in dry,Room Temperature
form Solid
pka 7.10±0.18(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
HS Code  2916399090
NFPA 704
1
2 0

3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 276114 3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 403-01-0 1g $360 2026-06-03 Buy
Usbiological 276114 3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 403-01-0 2g $489 2026-06-03 Buy
Usbiological 276114 3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 403-01-0 5g $729 2026-06-03 Buy
Usbiological 276114 3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 403-01-0 10g $1083 2026-06-03 Buy
Usbiological 276114 3-Fluoro-4-hydroxybenzoic acid methyl ester Asreported 403-01-0 25g $1593 2026-06-03 Buy
Product number Packaging Price Buy
276114 1g $360 Buy
276114 2g $489 Buy
276114 5g $729 Buy
276114 10g $1083 Buy
276114 25g $1593 Buy

3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Chemical Properties,Uses,Production

Synthesis

Methanol

67-56-1

3-Fluoro-4-hydroxybenzoic acid

350-29-8

3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER

403-01-0

Procedure for the synthesis of methyl 3-fluoro-4-hydroxybenzoate (T10.1): 3-fluoro-4-hydroxybenzoic acid (5.03 g, 32.22 mmol, commercially available from Sigma-Aldrich, St. Louis, MO, USA), methanol (50.0 mL), and cold sulfuric acid (2.0 mL) were added to a round bottom flask. The reaction mixture was heated to 80 °C and the progress of the reaction was monitored by thin layer chromatography (TLC). After 20.5 hours of reaction, the solvent was removed by distillation under reduced pressure. The residue was diluted with ether and the organic phase was sequentially washed twice with saturated aqueous sodium bicarbonate and once with brine, followed by drying with anhydrous sodium sulfate. After filtration, the organic solvent was removed by evaporation under reduced pressure to give the product T10.1 (4.79 g, 87% yield) as a white solid. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.81 (2H, m), 7.06 (1H, t, J = 8.4 Hz), 5.62 (1H, d, J = 4.3 Hz), 3.91 (3H, s).

References

[1] Patent: WO2010/45258, 2010, A2. Location in patent: Page/Page column 155
[2] Patent: WO2009/111056, 2009, A1. Location in patent: Page/Page column 227-228
[3] Patent: WO2008/87529, 2008, A1. Location in patent: Page/Page column 42; 43; 119-120
[4] Patent: WO2010/9290, 2010, A1. Location in patent: Page/Page column 58
[5] Patent: US2007/191603, 2007, A1. Location in patent: Page/Page column 35

3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 93)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10403 58
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Finetech Industry Limited
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Labnetwork lnc.
+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58

View Lastest Price from 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER pictures 2025-12-01 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
403-01-0
1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER pictures 2019-12-26 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
403-01-0
$1.00 1KG 99% 100KG Career Henan Chemical Co

3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Spectrum

3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER RARECHEM AL BF 0259 Fluoro-4-hydroxybenzoate Benzoic acid, 3-fluoro-4-hydroxy-, methyl ester METHYL 3-FLUORO-4-HYDROXYBENZOATE 403-01-0 blocks Carboxes FluoroCompounds pharmacetical