ChemicalBook >> CAS DataBase List >>4-Amino-2-(trifluoromethyl)benzonitrile
4-Amino-2-(trifluoromethyl)benzonitrile
- CAS No.
- 654-70-6
- Chemical Name:
- 4-Amino-2-(trifluoromethyl)benzonitrile
- Synonyms
- 4-AMINO-2-TRIFLUOROMETHYLBENZONITRILE;5-AMINO-2-CYANOBENZOTRIFLUORIDE;4-CYANO-3-TRIFLUOROMETHYLANILINE;4-Amino-2-(trifL;BUTTPARK 22\01-63;4-Amino-2-(trifluoro;Bicalutamide-EP-Imp-D;Enazalutamide Impurity A;BicalutaMide EP IMpurity D;Bicalutamide intermediate F
- CBNumber:
- CB9296914
- Molecular Formula:
- C8H5F3N2
- Molecular Weight:
- 186.13
- MDL Number:
- MFCD00042155
- MOL File:
- 654-70-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 06:26:20
| Product description | Number | Pack Size | Price |
| 4-Amino-2-(trifluoromethyl)benzonitrile 97% | 631752 | 1g | $27.5 |
| Bicalutamide impurity D British Pharmacopoeia (BP) Reference Standard | BP1116 | 10MG | $238 |
| 4-Amino-2-(trifluoromethyl)benzonitrile 97% | 631752 | 5g | $131 |
| 5-Amino-2-cyanobenzotrifluoride >98.0%(GC) | A1213 | 1g | $28 |
| 5-Amino-2-cyanobenzotrifluoride >98.0%(GC) | A1213 | 5g | $68 |
| More product size | |||
| Melting point | 141-145 °C(lit.) |
|---|---|
| Boiling point | 294.5±40.0 °C(Predicted) |
| Density | 1.37±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| form | Powder |
| pka | 0.50±0.10(Predicted) |
| color | White to off-white |
| BRN | 3278074 |
| InChI | InChI=1S/C8H5F3N2/c9-8(10,11)7-3-6(13)2-1-5(7)4-12/h1-3H,13H2 |
| InChIKey | PMDYLCUKSLBUHO-UHFFFAOYSA-N |
| SMILES | C(#N)C1=CC=C(N)C=C1C(F)(F)F |
| CAS DataBase Reference | 654-70-6(CAS DataBase Reference) |
| FDA UNII | L47D9XHC08 |
| NIST Chemistry Reference | 5-Amino-2-cyanobenzotrifluoride(654-70-6) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312+P330-P302+P352-P333+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 22-43-36/37/38-20/21/22 | |||||||||
| Safety Statements | 36-45-37/39-26 | |||||||||
| RIDADR | 3439 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29049090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Sens. 1 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
4-Amino-2-(trifluoromethyl)benzonitrile price More Price(81)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 631752 | 4-Amino-2-(trifluoromethyl)benzonitrile 97% | 654-70-6 | 1g | $27.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | BP1116 | Bicalutamide impurity D British Pharmacopoeia (BP) Reference Standard | 654-70-6 | 10MG | $238 | 2026-04-30 | Buy |
| Sigma-Aldrich | 631752 | 4-Amino-2-(trifluoromethyl)benzonitrile 97% | 654-70-6 | 5g | $131 | 2026-04-30 | Buy |
| TCI Chemical | A1213 | 5-Amino-2-cyanobenzotrifluoride >98.0%(GC) | 654-70-6 | 1g | $28 | 2026-04-30 | Buy |
| TCI Chemical | A1213 | 5-Amino-2-cyanobenzotrifluoride >98.0%(GC) | 654-70-6 | 5g | $68 | 2026-04-30 | Buy |
4-Amino-2-(trifluoromethyl)benzonitrile Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
4-Amino-2-(trifluoromethyl)benzonitrile is used for the preparation of benzene derivatives as non-steroidal androgen receptor modulators.
Uses
4-Amino-2-(trifluoromethyl)benzonitrile can serve as starting material in the synthesis of benzimidazoles, which can act as potential candidates in the treatment of breast cancer due to their ability to inhibit the growth of endothelial cells.


Synthesis of 4-Amino-2-(trifluoromethyl)benzonitrile from Benzaldehyde, 4-aMino-2-(trifluoroMethyl)-
4-Amino-2-(trifluoromethyl)benzonitrile Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 598)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Chontech Baocheng Chemical Co.,Ltd | +86-51982698291; +undefined15295095616 | info@hhbhswkj.com | China | 127 | 58 |
| Changzhou Zechong Biopharma Co., Ltd. | +undefined18621330623 | sales@zechongchem.com | China | 28 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 | justine@zhongda-biotech.com | China | 286 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
Related articles
- Application research of 4-amino-2-(trifluoromethyl)benzonitrile
- 4-Amino-2-(trifluoromethyl)benzonitrile is a useful pharmacophore found in the anticancer drug bicalutamide as a structural un....
- Oct 14,2025
View Lastest Price from 4-Amino-2-(trifluoromethyl)benzonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-06-05 | 4-Amino-2-(trifluoromethyl)benzonitrile
654-70-6
|
1KG | 99.5%min HPLC | 10 TONS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
![]() |
2026-05-28 | 4-Amino-2-(trifluoromethyl)benzonitrile
654-70-6
|
$10.70 | 10kg | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
![]() |
2025-09-25 | 4-Amino-2-(trifluoromethyl)benzonitrile
654-70-6
|
$2.00-10.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd |
-

- 4-Amino-2-(trifluoromethyl)benzonitrile
654-70-6
- $0.00
- 99.5%min HPLC
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- 4-Amino-2-(trifluoromethyl)benzonitrile
654-70-6
- $10.70
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-

- 4-Amino-2-(trifluoromethyl)benzonitrile
654-70-6
- $2.00-10.00
- 99%
- Henan Fengda Chemical Co., Ltd
654-70-6(4-Amino-2-(trifluoromethyl)benzonitrile)Related Search:
N,N-Dimethyl-1,4-phenylenediamine
Trifluoromethanesulfonic anhydride
Benzonitrile
p-Tolunitrile
3-(Trifluoromethyl)benzaldehyde
(Trifluoromethyl)trimethylsilane
3-(trifluoromethyl) Cinnamaldehyde
Tris(hydroxymethyl)aminomethane
Glycine
Aminoethoxyvinyl glycine hydrochloride
1of4
5-AMINO-2-CYANOBENZOTRIFLUORIDE
BUTTPARK 22\01-63
2-CYANO-5-AMINOBENZOTRIFLUORIDE
5-AMINO-2-CYANO BENZOTRIFLUORID
4-Amino-2-(trifluoromethyl)benzontrile
4-Bromo-2-TrifluoromethylAniline/4-Bromo-2-(Trifluoromethyl)Aniline/2-Amino-5-Bromobenzotrifluoride
4-Amino-2-trifluoromethylbenzotrile
Bicalutamide intermediate F
4-Amino-2-(Trifluoromethyl)Ben
4-AMINO-2-(TRIFIUOROMETHYL) BENZ-IMIDAZOLE
5-Amino-2-cyanobenzotrifluoride98%
2-CYANO-5-AMINOBENZOTRIFLUORIDE(2-TRIFLUOROMETHYL-4-AMINOBENZONITRILE)
Bicalutamide Impurity 6(EP Impurity D)
4-aMino -2-(three fluoroMethyl)benzonitrile
Benzonitrile,4-aMino-2-(trifluoroMethyl)-
AMino - 4-2-3 Methyl phenyl nitrile
4-Amino-2-(trifL
Bicalutamide-EP-Imp-D
2-Cyano-5-aminobenzenetrifluoride
3-Amino-6-cyanobenzotrifluoride
4-Amino-2-(trifluoromethyl)benzenecarbonitrile
4-Amino-2-trifluoromethylbenzenecarbonitrile
4-AMino-2-(trifluoroMethyl)...
4-Cyano-3-Trifluoromethylanili
2-Cyano-5-amino benzotrifluoride ,99%
4-Amino-2-(trifluoro
4-AMino-α,α,α-trifluoro-o-tolunitrile
4-Amino-2-trifluoromethylbenzonitrile
4-Cyano-3-trifluoromethylaniline
4-Amino-2-(trifluoromethyl)benzonitrile 98%
BicalutaMide EP IMpurity D
5-Amino-2-cyanobenzotrifluoride, 4-Cyano-3-(trifluoromethyl)aniline
5-Amino-2-cyanobenzotrifluoride >
Bicalutamide Impurity 6(Bicalutamide EP Impurity D)
4-Cyano-3-trifluromethyllaniline
2-Trifluoromethyl-4-aminobenzonitrile (Bicalutamide Impurity)
4-CYANO-3-TRIFLUOROMETHYLANILINE
Enazalutamide Impurity A
4-AMINO-2-TRIFLUOROMETHYLBENZONITRILE
654-70-6
654-70-7
NCC6H3CF3NH2
Cyanides/Nitriles
Nitrogen Compounds
Organic Building Blocks
C8 to C9
Building Blocks
Building Blocks for Liquid Crystals
Benzonitriles (Building Blocks for Liquid Crystals)
Amines
Aromatics
Phenyls & Phenyl-Het
Chemical intermediate for Bicalutamide
Aromatic Nitriles
Aromatic Halides (substituted)
Phenyls & Phenyl-Het
Aniline
Bicalutamide
Chemical Amines





