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Cetilistat Intermediate

CAS No.
890655-08-0
Chemical Name:
Cetilistat Intermediate
Synonyms
Cetilistat Intermediate;2-hexadecyloxycarbonyl-amino-5-methyl-benzoic acid;Benzoic acid, 2-[[(hexadecyloxy)carbonyl]amino]-5-methyl-
CBNumber:
CB93044301
Molecular Formula:
C25H41NO4
Molecular Weight:
419.6
MDL Number:
MFCD28899998
MOL File:
890655-08-0.mol
MSDS File:
SDS
Last updated:2025-04-18 09:53:07

Cetilistat Intermediate Properties

Boiling point 512.5±43.0 °C(Predicted)
Density 1.035±0.06 g/cm3(Predicted)
pka 3.77±0.36(Predicted)

Cetilistat Intermediate Chemical Properties,Uses,Production

Uses

Cetilistat impurity 1 is an impurity of Cetilistat. Cetilistat, an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively[1].

References

[1] Yamada Y, et al. Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in rats. Horm Metab Res. 2008 Aug;40(8):539-43. DOI:10.1055/s-2008-1076699

2941-78-8
26272-90-2
890655-08-0
Synthesis of Cetilistat Intermediate from 2-Amino-5-methylbenzoic acid and Cetyl chloroformate

Cetilistat Intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

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Cetilistat Intermediate 2-hexadecyloxycarbonyl-amino-5-methyl-benzoic acid Benzoic acid, 2-[[(hexadecyloxy)carbonyl]amino]-5-methyl- 890655-08-0