7-bromo-3-methylquinoline
- CAS No.
- 1375108-41-0
- Chemical Name:
- 7-bromo-3-methylquinoline
- Synonyms
- 7-bromo-3-methylquinoline;Quinoline, 7-bromo-3-methyl-
- CBNumber:
- CB93050023
- Molecular Formula:
- C10H8BrN
- Molecular Weight:
- 222.08
- MDL Number:
- MFCD23163642
- MOL File:
- 1375108-41-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
7-bromo-3-methylquinoline price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS116848 | 7-Bromo-3-methylquinoline 95% | 1375108-41-0 | 1g | $646 | 2026-06-04 | Buy |
| Matrix Scientific | 182799 | 7-Bromo-3-methylquinoline | 1375108-41-0 | 250.00mg | $118 | 2026-05-18 | Buy |
| Matrix Scientific | 182799 | 7-Bromo-3-methylquinoline | 1375108-41-0 | 1.00g | $355 | 2026-05-18 | Buy |
| Matrix Scientific | 182799 | 7-Bromo-3-methylquinoline | 1375108-41-0 | 5.00g | $1241 | 2026-05-18 | Buy |
| A1 Biochem Labs | A1-08626 | 7-Bromo-3-methylquinoline 0.95 | 1375108-41-0 | 1g | $300 | 2026-06-05 | Buy |
7-bromo-3-methylquinoline Chemical Properties, Uses, Production
Synthesis
59278-65-8
123-38-6
1375108-41-0
General procedure for the synthesis of 7-bromo-3-methylquinoline from 2-amino-4-bromobenzaldehyde and propionaldehyde: KOH (5.61 g, 100 mmol) was dissolved in ethanol (50 mL) to prepare a solution, which was subsequently added drop-wise to a reaction flask containing a 2-amino-4-bromobenzaldehyde (60.6 g, 303 mmol) and propionaldehyde (17.6 g, 303 mmol ) in a reaction flask of the mixture. Anhydrous ethanol (200 mL) was added to the reaction system under nitrogen protection. The reaction mixture was heated to reflux and the reflux reaction was maintained for 3 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated by rotary evaporator to remove ethanol. Water was added to the concentrated mixture and extracted with dichloromethane (3 x 100 mL). All organic layers were combined, washed with water and dried over anhydrous sodium sulfate, after which it was concentrated under vacuum. The crude product obtained was ground with ether to give the final 7-bromo-3-methylquinoline (48.6 g, 219 mmol, 72% yield) as a light brown solid. Mass spectrum (electrospray ionization) m/e 221.9, 223.9 [M + H]+ (bromine isotope mode).
References
[1] Patent: WO2014/108858, 2014, A1. Location in patent: Page/Page column 36
[2] Patent: WO2016/30443, 2016, A1. Location in patent: Page/Page column 99-100
7-bromo-3-methylquinoline Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuzhou Fukang Pharmaceutical Technology Co., Ltd. | 18150835816 | 120023275@qq.com | China | 908 | 58 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4905 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Pingguo Pharmaceutical Co., Ltd. | 021-20432229 | 2412110556@qq.com | China | 6016 | 55 |
| Shanghai Latchem Co., Ltd. | 021-61916491 15921747686 | sales@latcheminc.com | China | 963 | 58 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Nanjing xiangrui technology co. LTD | 021-021-00000000 15715199582 | njrich168@163.com | China | 501 | 58 |
| Birdo (Shanghai) Medical Technology Co., Ltd. | 021-58099077-8041 18601625411 | sales@birdotech.com | China | 9379 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Shanghai Ruipu Medical Technology Co., Ltd | 15895968936 | 1018762393@qq.com | China | 9992 | 58 |
