tert-Butyl 3-(2-bromoethyl)azetidine-1-carboxylate
- CAS No.
- 1420859-80-8
- Chemical Name:
- tert-Butyl 3-(2-bromoethyl)azetidine-1-carboxylate
- Synonyms
- 1-Boc-3-(2-bromoethyl)azetidine;tert-Butyl 3-(2-bromoethyl)azetidine-1-carboxylate;3-(2-Bromo-ethyl)-azetidine-1-carboxylic acid tert-butyl ester;1-Azetidinecarboxylic acid, 3-(2-bromoethyl)-, 1,1-dimethylethyl ester
- CBNumber:
- CB93052845
- Molecular Formula:
- C10H18BrNO2
- Molecular Weight:
- 264.16
- MDL Number:
- MFCD24382790
- MOL File:
- 1420859-80-8.mol
| Product description | Number | Pack Size | Price |
| tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate | B997030 | 25mg | $265 |
| Tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate | 0108DV | 100mg | $856 |
| Tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate | 0108DV | 2.5g | $2366 |
| tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate 95% | CM284027 | 5g | $1869 |
| tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate 95+% | CD11260495 | 5g | $1980 |
| Boiling point | 298.1±13.0 °C(Predicted) |
|---|---|
| Density | 1.320±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| pka | -1.68±0.40(Predicted) |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C10H18BrNO2/c1-10(2,3)14-9(13)12-6-8(7-12)4-5-11/h8H,4-7H2,1-3H3 |
| InChIKey | IMCAWEYWTGJUEH-UHFFFAOYSA-N |
| SMILES | N1(C(OC(C)(C)C)=O)CC(CCBr)C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
tert-Butyl 3-(2-bromoethyl)azetidine-1-carboxylate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B997030 | tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate | 1420859-80-8 | 25mg | $265 | 2021-12-16 | Buy |
| AK Scientific | 0108DV | Tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate | 1420859-80-8 | 100mg | $856 | 2021-12-16 | Buy |
| AK Scientific | 0108DV | Tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate | 1420859-80-8 | 2.5g | $2366 | 2021-12-16 | Buy |
| Chemenu | CM284027 | tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate 95% | 1420859-80-8 | 5g | $1869 | 2021-12-16 | Buy |
| Crysdot | CD11260495 | tert-Butyl3-(2-bromoethyl)azetidine-1-carboxylate 95+% | 1420859-80-8 | 5g | $1980 | 2021-12-16 | Buy |
tert-Butyl 3-(2-bromoethyl)azetidine-1-carboxylate Chemical Properties,Uses,Production
Synthesis
152537-03-6
1420859-80-8
General procedure for the synthesis of tert-butyl 3-(2-bromoethyl)azetidine-1-carboxylate from tert-butyl 3-(2-hydroxyethyl)azetidine-1-carboxylate: To a solution of tert-butyl 3-(2-hydroxyethyl)azetidine-1-carboxylate (6.1 g, 30.3 mmol) in dichloromethane (100 mL) was added, in sequence, at 0 °C carbon tetrabromide (19.8 g 60.6 mmol) and triphenylphosphine (15.7 g, 60.6 mmol). The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the mixture was concentrated and the residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=100:1) to afford tert-butyl 3-(2-bromoethyl)azetidine-1-carboxylate (5.5 g, 69.4% yield) as a colorless oil.LC-MS m/z: 208 [M+H-56].
References
[1] Patent: WO2017/27684, 2017, A1. Location in patent: Paragraph 00255
tert-Butyl 3-(2-bromoethyl)azetidine-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-Butyl 3-(2-bromoethyl)azetidine-1-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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