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tert-butyl N-methoxycarbamate

CAS No.
58377-44-9
Chemical Name:
tert-butyl N-methoxycarbamate
Synonyms
N-Boc-O-methylhydroxylamine;tert-Butyl methoxycarbamate;tert-butyl N-methoxycarbamate;Carbamic acid, N-methoxy-, 1,1-dimethylethyl ester
CBNumber:
CB93060637
Molecular Formula:
C6H13NO3
Molecular Weight:
147.17
MDL Number:
MFCD21140572
MOL File:
58377-44-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:54
Product description Number Pack Size Price
N-Boc-O-methylHydroxylamine B657050 1g $165
tert-Butyl N-methoxycarbamate 179522 1g $248
tert-Butyl N-methoxycarbamate 179522 5g $743
tert-Butylmethoxycarbamate 95+% CD13010079 10g $357
N-Boc-O-methylhydroxylamine 97% AS00419 10g $366.67

tert-butyl N-methoxycarbamate Properties

Boiling point 83-84 °C(Press: 10 Torr)
Density 1.006±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H302-H315-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P

tert-butyl N-methoxycarbamate price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B657050 N-Boc-O-methylHydroxylamine 58377-44-9 1g $165 2021-12-16 Buy
Matrix Scientific 179522 tert-Butyl N-methoxycarbamate 58377-44-9 1g $248 2021-12-16 Buy
Matrix Scientific 179522 tert-Butyl N-methoxycarbamate 58377-44-9 5g $743 2021-12-16 Buy
Crysdot CD13010079 tert-Butylmethoxycarbamate 95+% 58377-44-9 10g $357 2021-12-16 Buy
Acrotein AS00419 N-Boc-O-methylhydroxylamine 97% 58377-44-9 10g $366.67 2021-12-16 Buy
Product number Packaging Price Buy
B657050 1g $165 Buy
179522 1g $248 Buy
179522 5g $743 Buy
CD13010079 10g $357 Buy
AS00419 10g $366.67 Buy

tert-butyl N-methoxycarbamate Chemical Properties,Uses,Production

Uses

N-Boc-O-methyl Hydroxylamine is used to prepare (pyridinylmethylamino)furanones as insecticides.

Synthesis

Di-tert-butyl dicarbonate

24424-99-5

Methoxyamine Hydrochloride

593-56-6

tert-butyl N-methoxycarbamate

58377-44-9

Example 20: General procedure for the synthesis of tert-butyl methoxycarbamate from di-tert-butyl dicarbonate and methoxyamine hydrochloride Step A: Boc-protected amine (12.0 g, 55.0 mmol) was dissolved in dichloromethane (100 mL) and aqueous sodium carbonate solution (17.5 g sodium carbonate dissolved in 100 mL of water) was added. The reaction mixture was stirred at room temperature for 18 hours. After completion of the reaction, the organic layer was separated, washed with water, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give a clear oily product (7.94 g, 98% yield).

References

[1] Patent: WO2008/42928, 2008, A2. Location in patent: Page/Page column 48-49
[2] Patent: WO2008/42928, 2008, A2. Location in patent: Page/Page column 48-49
[3] Journal of Organic Chemistry, 1989, vol. 54, # 14, p. 3394 - 3403
[4] Organic and Biomolecular Chemistry, 2012, vol. 10, # 17, p. 3519 - 3530

tert-butyl N-methoxycarbamate Preparation Products And Raw materials

tert-butyl N-methoxycarbamate Suppliers

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong chuangyingchemical Co., Ltd.
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Nextpeptide Inc
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VladaChem GmbH
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HANGZHOU LEAP CHEM CO., LTD.
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Sichuan Biosynce Pharmatech Co., Ltd.
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Aladdin Scientific
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Compound Net Biotechnology Inc.
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Amadis Chemical Company Limited
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Shanghai Raise Chemical Technology Co.,Ltd 15026594951 rs@raise-chem.com China 4548 55
Beijing FYF Chemicals Co., Ltd 010-57903446 15869909019 168931144@qq.com China 2874 58

tert-butyl N-methoxycarbamate Spectrum

tert-butyl N-methoxycarbamate tert-Butyl methoxycarbamate N-Boc-O-methylhydroxylamine Carbamic acid, N-methoxy-, 1,1-dimethylethyl ester 58377-44-9