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Methyl 2-chlorothiophene-3-carboxylate

CAS No.
76360-42-4
Chemical Name:
Methyl 2-chlorothiophene-3-carboxylate
Synonyms
Methyl2-chlorothiophene-3-carboxylat;Methyl 2-chlorothiophene-3-carboxylate;3-Thiophenecarboxylic acid, 2-chloro3-Thiophenecarboxylic acid, 2-chloro-, m3-Thiophenecarboxylic acid, 2-chloro-, methyl esterethyl ester-, methyl ester
CBNumber:
CB93066356
Molecular Formula:
C6H5ClO2S
Molecular Weight:
176.62
MDL Number:
MFCD14698135
MOL File:
76360-42-4.mol
Last updated:2025-07-24 18:13:48

Methyl 2-chlorothiophene-3-carboxylate Properties

Boiling point 107-112 °C(Press: 15 Torr)
Density 1.371±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
InChI InChI=1S/C6H5ClO2S/c1-9-6(8)4-2-3-10-5(4)7/h2-3H,1H3
InChIKey GVIPSISZNQFLRF-UHFFFAOYSA-N
SMILES C1(Cl)SC=CC=1C(OC)=O

Methyl 2-chlorothiophene-3-carboxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS115770 Methyl 2-chlorothiophene-3-carboxylate 95% 76360-42-4 1g $169 2026-06-04 Buy
Activate Scientific AS115770 Methyl 2-chlorothiophene-3-carboxylate 95% 76360-42-4 5g $644 2026-06-04 Buy
Activate Scientific AS115770 Methyl 2-chlorothiophene-3-carboxylate 95% 76360-42-4 25g $1653 2026-06-04 Buy
aablocks AA00ICNM Methyl 2-chlorothiophene-3-carboxylate 98% 76360-42-4 250mg $74 2026-05-29 Buy
aablocks AA00ICNM Methyl 2-chlorothiophene-3-carboxylate 98% 76360-42-4 1g $174 2026-05-29 Buy
Product number Packaging Price Buy
AS115770 1g $169 Buy
AS115770 5g $644 Buy
AS115770 25g $1653 Buy
AA00ICNM 250mg $74 Buy
AA00ICNM 1g $174 Buy

Methyl 2-chlorothiophene-3-carboxylate Chemical Properties, Uses, Production

Synthesis

Methanol

67-56-1

2-Chlorothiophene-3-carboxylic acid

53935-71-0

Methyl 2-chlorothiophene-3-carboxylate

76360-42-4

To a 100 mL round bottom flask was added 2-chloro-3-thiophenecarboxylic acid (3 g, 18.45 mmol) and methanol (50 mL). With stirring at 0 °C, thionyl chloride (4.4 g, 37.29 mmol) was added slowly and dropwise. The reaction mixture was continued to be stirred at room temperature for 3 hours. Upon completion of the reaction, the reaction solution was concentrated under reduced pressure by rotary evaporator. The concentrated residue was purified by silica gel column chromatography using ethyl acetate/petroleum ether (1:10 to 1:8) as eluent. Finally, 3.2 g of methyl 2-chlorothiophene-3-carboxylate was obtained in 98% yield as a yellow oil.

References

[1] Patent: WO2017/184624, 2017, A1. Location in patent: Page/Page column 180; 181
[2] Patent: WO2018/109643, 2018, A1. Location in patent: Page/Page column 104; 106

67-56-1
53935-71-0
76360-42-4
Synthesis of Methyl 2-chlorothiophene-3-carboxylate from Methanol and 2-Chlorothiophene-3-carboxylic acid

Methyl 2-chlorothiophene-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl 2-chlorothiophene-3-carboxylate Suppliers

Global Suppliers ( 23)
Supplier Tel Email Country ProdList Advantage
Beijing Lakefort Technology Co., Ltd 18515589492; 18515589492 mhchangtong@126.com China 96 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
BePharm Ltd 400-685-9117 market@bepharm.com China 15081 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shanghai Rlavie Technology Co., Ltd. 021-67759270 17717059219 sales@rlavie.com China 1850 55
Suzhou Rovathin Foreign Trade Co.,Ltd 0512-65816829 18662214788 info@rovathin.com.cn China 9959 58
Xinyi Kaiwu Chemical Technology Co., Ltd. 0516-0516-88997009 18651776937 4164357@qq.com China 3204 58
Shanghai Rlavie Technology Co ltd +86-021-67759270 +86-17717059219 sales@rlavie.com China 1030 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946 1461866103@qq.com China 16103 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58

View Latest Price from Methyl 2-chlorothiophene-3-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
methyl 2-chlorothiophene-3-carboxylate pictures 2022-01-04 methyl 2-chlorothiophene-3-carboxylate
76360-42-4
1g 98%minGC 50kgs/month Shanghai Rlavie Technology Co ltd
Methyl 2-chlorothiophene-3-carboxylate 3-Thiophenecarboxylic acid, 2-chloro3-Thiophenecarboxylic acid, 2-chloro-, m3-Thiophenecarboxylic acid, 2-chloro-, methyl esterethyl ester-, methyl ester Methyl2-chlorothiophene-3-carboxylat 76360-42-4