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Cilazapril

Cilazapril Structure
Cilazapril structure
CAS No.
88768-40-5
Chemical Name:
Cilazapril
Synonyms
Vascace;(1S,9S)-;Yipingshu;Ro34-2848;Cilazapril;Ro 31-2848;Ro 34-2848;Ro-34-2848;CILASTATIN NA;Cilazapril USP/EP/BP
CBNumber:
CB9307140
Molecular Formula:
C22H31N3O5
Molecular Weight:
417.5
MDL Number:
MFCD00865788
MOL File:
88768-40-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:27:59
Product description Number Pack Size Price
Cilazapril ≥98% 29777 1mg $36
Cilazapril ≥98% 29777 5mg $86
Cilazapril ≥98% 29777 10mg $135
Cilazapril ≥98% 29777 25mg $294
Cilazapril 29777 1mg $32
More product size
Request For Quotation

Cilazapril Properties

Melting point 95-97°C
Boiling point 598.1±60.0 °C(Predicted)
Density 1.26±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form powder
pka 2.28±0.20(Predicted)
color White to Off-White
CAS DataBase Reference 88768-40-5(CAS DataBase Reference)
FDA UNII 8Q9454114Q
ATC code C09AA08

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  22-24/25
WGK Germany  3
RTECS  MJ9650200

Cilazapril price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29777 Cilazapril ≥98% 88768-40-5 1mg $36 2026-04-30 Buy
Cayman Chemical 29777 Cilazapril ≥98% 88768-40-5 5mg $86 2026-04-30 Buy
Cayman Chemical 29777 Cilazapril ≥98% 88768-40-5 10mg $135 2026-04-30 Buy
Cayman Chemical 29777 Cilazapril ≥98% 88768-40-5 25mg $294 2026-04-30 Buy
Cayman Chemical 29777 Cilazapril 88768-40-5 1mg $32 2024-03-01 Buy
Product number Packaging Price Buy
29777 1mg $36 Buy
29777 5mg $86 Buy
29777 10mg $135 Buy
29777 25mg $294 Buy
29777 1mg $32 Buy

Cilazapril Chemical Properties,Uses,Production

Description

Cilazapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor cilazaprilat. In vivo, cilazapril (0.1 mg/kg) inhibits plasma ACE activity and inhibits the angiotensin I-induced pressor response in anesthetized rats and cats. It decreases systolic blood pressure in spontaneously hypertensive rats when administered at a dose of 30 mg/kg. Cilazapril (10 mg/kg, p.o.) decreases blood pressure in volume-depleted renal hypertensive dogs. Formulations containing cilazapril have been used in the treatment of hypertension.

Chemical Properties

Off-White Solid

Uses

An ACE inhibitor. Hydrolyzed in vivo to the active diacid metabolite (Cilazaprilat). Antihypertensive.

Definition

ChEBI: Cilazapril is a pyridazinodiazepine resulting from the formal condensation of the carboxy group of cilazaprilat with ethanol. It is a drug used in the treatment of hypertension and heart failure. It has a role as a prodrug, an antihypertensive agent and an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It is an ethyl ester, a pyridazinodiazepine and a dicarboxylic acid monoester. It is functionally related to a Cilazaprilat.

brand name

Inhibace (Hoffmann-LaRoche).

References

[1] WATERFALL J. A review of the preclinical cardiovascular pharmacology of cilazapril, a new angiotensin converting enzyme inhibitor.[J]. British journal of clinical pharmacology, 1989, 27 S2: 139S-150S. DOI: 10.1111/j.1365-2125.1989.tb03475.x

Cilazapril Preparation Products And Raw materials

Raw materials

Preparation Products

Cilazapril Suppliers

Global( 94)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 10000 58
Baoji Guokang Healthchem Co., Ltd. 		+86-0917-3909592 +86-13892490616 gksales1@gk-bio.com China 9072 58
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19853 58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd 		027-88013699 17354350817 Ryan@jiutian-bio.com China 5945 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Supplier Advantage
career henan chemical co 		58
CONIER CHEM AND PHARMA LIMITED 		58
TargetMol Chemicals Inc. 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Baoji Guokang Healthchem Co., Ltd. 		58
BOC Sciences 		58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd 		58
Aladdin Scientific 		58
Chongqing Chemdad Co., Ltd 		58
Amadis Chemical Company Limited 		58

View Lastest Price from Cilazapril manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cilazapril pictures 2021-07-13 Cilazapril
88768-40-5
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Cilazapril pictures 2021-07-10 Cilazapril
88768-40-5
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Cilazapril pictures 2020-05-10 Cilazapril
88768-40-5
 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
  • Cilazapril pictures
  • Cilazapril
    88768-40-5
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • Cilazapril pictures
  • Cilazapril
    88768-40-5
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • Cilazapril pictures
  • Cilazapril
    88768-40-5
  • 99.0%
  • Shaanxi Dideu Medichem Co. Ltd

88768-40-5(Cilazapril)Related Search:

DELAPRIL Lithium diisopropylamide DIAZOXIDE Cilazapril Monohydrate Carbonyl iron powder
NITROUS OXIDE Ethyl N-(2-butyl)glycinate 2,2'-(ETHYLENEDIIMINO)-DIBUTYRIC ACID Cilastatin sodium Cilastatin
Cilazaprilat L-Homophenylalanine ethyl ester L-β-Homophenylalanine, HPLC 98% CILAZAPRIL CILAZAPRIL IMPURITY D
CILAZAPRIL IMPURITY A HEXAHYDROPYRIDAZINE-3-CARBOXYLIC ACID Cilazapril

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6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, (1S,9S)- 6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 9-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, [1S-[1α,9α(R*)]]- Ro 31-2848 Yipingshu CILASTATIN NA CILASTATIN SODIUM SALT sodium hydrogen 7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate (1S,9S)-9-[(S)-1-Ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid Cilazapril (1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-α][1,2]diazepine-1-carboxylic Acid Vascace (1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid (1S,9S)-9-[[(S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid (1S,9S)- (1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic Acid Cilazapril USP/EP/BP Cilazapril (anhydrous) Ro 34-2848 Ro-34-2848 Ro34-2848 88768-40-5 Chiral Reagents API Intermediates & Fine Chemicals Pharmaceuticals