5-AMINO-1-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
- CAS No.
- 5394-41-2
- Chemical Name:
- 5-AMINO-1-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
- Synonyms
- BUTTPARK 51\09-67;3-AMINO-4-CYANO-1-(4-NITROPHENYL)PYRAZOLE;5-amino-4-cyano-1 - (4-nitrophenyl) pyrazole;5-AMINO-1-(4-NITROPHENYL)PYRAZOLE-4-CARBONITRILE;5-azanyl-1-(4-nitrophenyl)pyrazole-4-carbonitrile;5-AMINO-1-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE;1H-Pyrazole-4-carbonitrile, 5-amino-1-(4-nitrophenyl)-
- CBNumber:
- CB9312340
- Molecular Formula:
- C10H7N5O2
- Molecular Weight:
- 229.19
- MDL Number:
- MFCD00052885
- MOL File:
- 5394-41-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Amino-1-(4-nitrophenyl)pyrazole-4-carbonitrile Asreported | 260218 | 500mg | $240 |
| 5-Amino-1-(4-nitrophenyl)pyrazole-4-carbonitrile Asreported | 260218 | 1g | $355 |
| 5-Amino-1-(4-nitrophenyl)pyrazole-4-carbonitrile 97% | C015 | 1g | $21 |
| 5-Amino-1-(4-nitrophenyl)pyrazole-4-carbonitrile 97% | C015 | 5g | $66 |
| 5-Amino-1-(4-nitrophenyl)-1H-pyrazole-4-carbonitrile | 044369 | 500.00mg | $118 |
| More product size | |||
| Melting point | 191-193 |
|---|---|
| Boiling point | 492.3±40.0 °C(Predicted) |
| Density | 1.51±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | -2.01±0.10(Predicted) |
| Appearance | Yellow to orange Solid |
| InChI | InChI=1S/C10H7N5O2/c11-5-7-6-13-14(10(7)12)8-1-3-9(4-2-8)15(16)17/h1-4,6H,12H2 |
| InChIKey | OAPYCPXMCXWPHI-UHFFFAOYSA-N |
| SMILES | N1(C2=CC=C([N+]([O-])=O)C=C2)C(N)=C(C#N)C=N1 |
| CAS DataBase Reference | 5394-41-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xi |
|---|---|
| HazardClass | IRRITANT |
| HS Code | 2933199090 |
5-AMINO-1-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 260218 | 5-Amino-1-(4-nitrophenyl)pyrazole-4-carbonitrile Asreported | 5394-41-2 | 500mg | $240 | 2026-06-03 | Buy |
| Usbiological | 260218 | 5-Amino-1-(4-nitrophenyl)pyrazole-4-carbonitrile Asreported | 5394-41-2 | 1g | $355 | 2026-06-03 | Buy |
| AK Scientific | C015 | 5-Amino-1-(4-nitrophenyl)pyrazole-4-carbonitrile 97% | 5394-41-2 | 1g | $21 | 2026-06-04 | Buy |
| AK Scientific | C015 | 5-Amino-1-(4-nitrophenyl)pyrazole-4-carbonitrile 97% | 5394-41-2 | 5g | $66 | 2026-06-04 | Buy |
| Matrix Scientific | 044369 | 5-Amino-1-(4-nitrophenyl)-1H-pyrazole-4-carbonitrile | 5394-41-2 | 500.00mg | $118 | 2026-05-18 | Buy |
5-AMINO-1-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Chemical Properties,Uses,Production
Synthesis
100-16-3
123-06-8
5394-41-2
Step 1: To a mixed solution of 5.0 g (32.65 mmol) of 4-nitrophenylhydrazine and 9.10 mL (65.3 mmol) of N,N-diethylethylamine in 90 mL of ethanol was added 3.987 g (32.65 mmol) of ethoxymethylene malononitrile. The reaction mixture was stirred under reflux conditions overnight and subsequently cooled to room temperature. The reaction solution was concentrated and the residue was dissolved in dichloromethane, washed sequentially with water and brine, dried over anhydrous sodium sulfate and concentrated. The resulting solid was treated with hexane, filtered and dried under vacuum to afford 7.024 g (91% yield) of the target product 5-amino-1-(4-nitrophenyl)-1H-pyrazole-4-carbonitrile, which could be used in the next reaction without further purification.
References
[1] Patent: WO2013/182612, 2013, A1. Location in patent: Page/Page column 146
[2] European Journal of Medicinal Chemistry, 2008, vol. 43, # 4, p. 771 - 780
[3] Journal of Medicinal Chemistry, 1991, vol. 34, # 9, p. 2892 - 2898
[4] Organic and Biomolecular Chemistry, 2007, vol. 5, # 17, p. 2758 - 2761
[5] RSC Advances, 2015, vol. 5, # 68, p. 55179 - 55185
5-AMINO-1-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| Zhongshan Jukemei Biotechnology Co., Ltd. | 13642727863 | 1009049100@qq.com | China | 656 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35896 | 56 |
5394-41-2(5-AMINO-1-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE)Related Search:
1of3
