UNC3866
- CAS No.
- 1872382-47-2
- Chemical Name:
- UNC3866
- Synonyms
- methyl (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(4-tert-butylbenzoyl)amino]-3-phenylpropanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-6-(diethylamino)hexanoyl]amino]-3-hydroxypropanoate;CS-2491;UNC3866;UNC 3866;UNC-3866;UNC3866, 10 mM in DMSO;UNC3866,inhibit,Histone Methyltransferase,UNC-3866,Inhibitor,UNC 3866;N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine methyl ester;L-Serine, N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-, methyl ester;(3S,6S,9S,12S,15S)-Methyl 3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate
- CBNumber:
- CB93153225
- Molecular Formula:
- C43H66N6O8
- Molecular Weight:
- 795.02
- MDL Number:
- MFCD30536205
- MOL File:
- 1872382-47-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| UNC3866 ≥95% | 19237 | 1mg | $53 |
| UNC3866 ≥95% | 19237 | 5mg | $168 |
| UNC3866 ≥95% | 19237 | 10mg | $306 |
| UNC3866 ≥95% | 19237 | 25mg | $636 |
| UNC3866 ≥95% | 19237 | 1mg | $48 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
UNC3866 price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19237 | UNC3866 ≥95% | 1872382-47-2 | 1mg | $53 | 2026-04-30 | Buy |
| Cayman Chemical | 19237 | UNC3866 ≥95% | 1872382-47-2 | 5mg | $168 | 2026-04-30 | Buy |
| Cayman Chemical | 19237 | UNC3866 ≥95% | 1872382-47-2 | 10mg | $306 | 2026-04-30 | Buy |
| Cayman Chemical | 19237 | UNC3866 ≥95% | 1872382-47-2 | 25mg | $636 | 2026-04-30 | Buy |
| Cayman Chemical | 19237 | UNC3866 ≥95% | 1872382-47-2 | 1mg | $48 | 2024-03-01 | Buy |
UNC3866 Chemical Properties,Uses,Production
Description
UNC3866 is an inhibitor of chromobox homolog 7 (CBX7; Kd = 97 nM). It also binds to CBX4 (Kd = 94 nM) but is greater than 6-fold selective over CBX2, 6, and 8 and the chromodomain Y family (CDY) chromodomains CDY1, L1b, and L2 (Kds = 0.61-6.3 μM). UNC3866 pretreatment (30 μM) of PC3 lysates completely inhibits chemiprecipitation of CBX7. It induces a senescent-like morphology and reduces growth of PC3 cells with an EC50 value of 7.6 μM.
Uses
Polycomb group proteins (CBX4, CBX7) regulate cell fate decisions during embryogenesis. N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine Methyl Ester is a selective antagonist of CBX4 and CBX7 chromodomains. It also inhibits prostate cell proliferation.
UNC3866 Preparation Products And Raw materials
Raw materials
Preparation Products
UNC3866 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11680 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9945 | 58 |







