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4-Fluoro-3-hydroxybenzyl alcohol

CAS No.
934241-78-8
Chemical Name:
4-Fluoro-3-hydroxybenzyl alcohol
Synonyms
2-Fluoro-5-(hydroxymethyl)phenol;4-Fluoro-3-hydroxybenzyl alcohol;Benzenemethanol, 4-fluoro-3-hydroxy-;2-Fluoro-5-(hydroxymethyl)phenol 95+%
CBNumber:
CB93154530
Molecular Formula:
C7H7FO2
Molecular Weight:
142.13
MDL Number:
MFCD12031832
MOL File:
934241-78-8.mol
MSDS File:
SDS
Last updated:2026-05-28 06:29:50
Product description Number Pack Size Price
2-Fluoro-5-(hydroxymethyl)phenol 97% PC53135 250mg $49
2-Fluoro-5-(hydroxymethyl)phenol 97% PC53135 1g $130
2-Fluoro-5-(hydroxymethyl)phenol 97% PC53135 5g $460
2-Fluoro-5-(hydroxymethyl)phenol 97% PC53135 25g $1783
2-Fluoro-5-(hydroxymethyl)phenol 97% PC53135 250mg $49

4-Fluoro-3-hydroxybenzyl alcohol Properties

Boiling point 272.4±25.0 °C(Predicted)
Density 1.342±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 8.49±0.10(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2908190090

4-Fluoro-3-hydroxybenzyl alcohol price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC53135 2-Fluoro-5-(hydroxymethyl)phenol 97% 934241-78-8 250mg $49 2026-06-04 Buy
Apolloscientific PC53135 2-Fluoro-5-(hydroxymethyl)phenol 97% 934241-78-8 1g $130 2026-06-04 Buy
Apolloscientific PC53135 2-Fluoro-5-(hydroxymethyl)phenol 97% 934241-78-8 5g $460 2026-06-04 Buy
Apolloscientific PC53135 2-Fluoro-5-(hydroxymethyl)phenol 97% 934241-78-8 25g $1783 2026-06-04 Buy
Apolloscientific PC53135 2-Fluoro-5-(hydroxymethyl)phenol 97% 934241-78-8 250mg $49 2026-06-04 Buy
Product number Packaging Price Buy
PC53135 250mg $49 Buy
PC53135 1g $130 Buy
PC53135 5g $460 Buy
PC53135 25g $1783 Buy
PC53135 250mg $49 Buy

4-Fluoro-3-hydroxybenzyl alcohol Chemical Properties,Uses,Production

Synthesis

METHYL 4-FLUORO-3-HYDROXYBENZOATE

214822-96-5

4-Fluoro-3-hydroxybenzyl alcohol

934241-78-8

The general procedure for the synthesis of 4-fluoro-3-hydroxybenzyl alcohol from methyl 4-fluoro-3-hydroxybenzoate was as follows: LiBH4 (2.37 g, 109 mmol) was suspended in THF (50 mL) at room temperature, followed by the addition of methyl 4-fluoro-3-hydroxybenzoate (5.0 g, 27.2 mmol). The reaction mixture was stirred under reflux conditions for 24 hours. After completion of the reaction, the mixture was concentrated. The residue was partitioned between EtOAc (100 mL) and 1N HCl (100 mL). The aqueous layer was extracted with EtOAc (50 mL × 2) and the combined organic layers were washed with brine, dried over MgSO4 and concentrated. The residue was purified by fast column chromatography to afford 4-fluoro-3-hydroxybenzyl alcohol (2.76 g, 19.4 mmol, 66% yield) as a white solid.1H NMR (CDCl3) δ: 7.09-7.00 (2H, m), 6.88-6.82 (1H, m), 5.24 (1H, d, J = 4.0 Hz), 4.60 (2H, s) , 1.68 (1H, brs).

References

[1] Patent: US2011/136801, 2011, A1. Location in patent: Page/Page column 64

4-Fluoro-3-hydroxybenzyl alcohol Preparation Products And Raw materials

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4-Fluoro-3-hydroxybenzyl alcohol Spectrum

4-Fluoro-3-hydroxybenzyl alcohol 2-Fluoro-5-(hydroxymethyl)phenol 2-Fluoro-5-(hydroxymethyl)phenol 95+% Benzenemethanol, 4-fluoro-3-hydroxy- 934241-78-8