4-Fluoro-3-hydroxybenzyl alcohol
- CAS No.
- 934241-78-8
- Chemical Name:
- 4-Fluoro-3-hydroxybenzyl alcohol
- Synonyms
- 2-Fluoro-5-(hydroxymethyl)phenol;4-Fluoro-3-hydroxybenzyl alcohol;Benzenemethanol, 4-fluoro-3-hydroxy-;2-Fluoro-5-(hydroxymethyl)phenol 95+%
- CBNumber:
- CB93154530
- Molecular Formula:
- C7H7FO2
- Molecular Weight:
- 142.13
- MDL Number:
- MFCD12031832
- MOL File:
- 934241-78-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2908190090 |
4-Fluoro-3-hydroxybenzyl alcohol price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC53135 | 2-Fluoro-5-(hydroxymethyl)phenol 97% | 934241-78-8 | 250mg | $49 | 2026-06-04 | Buy |
| Apolloscientific | PC53135 | 2-Fluoro-5-(hydroxymethyl)phenol 97% | 934241-78-8 | 1g | $130 | 2026-06-04 | Buy |
| Apolloscientific | PC53135 | 2-Fluoro-5-(hydroxymethyl)phenol 97% | 934241-78-8 | 5g | $460 | 2026-06-04 | Buy |
| Apolloscientific | PC53135 | 2-Fluoro-5-(hydroxymethyl)phenol 97% | 934241-78-8 | 25g | $1783 | 2026-06-04 | Buy |
| Activate Scientific | AS116684 | 4-Fluoro-3-hydroxybenzyl alcohol 97% | 934241-78-8 | 1g | $137 | 2026-06-04 | Buy |
4-Fluoro-3-hydroxybenzyl alcohol Chemical Properties, Uses, Production
Synthesis
214822-96-5
934241-78-8
The general procedure for the synthesis of 4-fluoro-3-hydroxybenzyl alcohol from methyl 4-fluoro-3-hydroxybenzoate was as follows: LiBH4 (2.37 g, 109 mmol) was suspended in THF (50 mL) at room temperature, followed by the addition of methyl 4-fluoro-3-hydroxybenzoate (5.0 g, 27.2 mmol). The reaction mixture was stirred under reflux conditions for 24 hours. After completion of the reaction, the mixture was concentrated. The residue was partitioned between EtOAc (100 mL) and 1N HCl (100 mL). The aqueous layer was extracted with EtOAc (50 mL × 2) and the combined organic layers were washed with brine, dried over MgSO4 and concentrated. The residue was purified by fast column chromatography to afford 4-fluoro-3-hydroxybenzyl alcohol (2.76 g, 19.4 mmol, 66% yield) as a white solid.1H NMR (CDCl3) δ: 7.09-7.00 (2H, m), 6.88-6.82 (1H, m), 5.24 (1H, d, J = 4.0 Hz), 4.60 (2H, s) , 1.68 (1H, brs).
References
[1] Patent: US2011/136801, 2011, A1. Location in patent: Page/Page column 64
4-Fluoro-3-hydroxybenzyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
4-Fluoro-3-hydroxybenzyl alcohol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
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| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Suzhou Rovathin Foreign Trade Co.,Ltd | 0512-65816829 18662214788 | info@rovathin.com.cn | China | 9961 | 58 |
| Henan Pusai Chemical Products Co., Ltd. | 0371-63357898 | 1280786222@qq.com | China | 3688 | 58 |
| Changzhou Yinghao Technology Development Co., Ltd | 15151934985 | sales@yingsapharm.com | China | 5455 | 58 |
| Weihai Huaixin Biotechnology Co., Ltd | 15662379806 | 845423637@qq.com | China | 2807 | 58 |
| Hubei Co-prosperity Medicine Technonlogy Co., Ltd | 2383948258 19172820304 | 2383948258@qq.com | China | 12983 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39796 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
