Azido-PEG3-Sulfone-PEG4-acid
- CAS No.
- 2055024-42-3
- Chemical Name:
- Azido-PEG3-Sulfone-PEG4-acid
- Synonyms
- Azido-PEG3-Sulfone-PEG4-acid;4,7,10,13,19,22,25-Heptoxa-16-thiaheptacosanoic acid, 27-azido-, 16,16-dioxide
- CBNumber:
- CB93162872
- Molecular Formula:
- C19H37N3O11S
- Molecular Weight:
- 515.58
- MDL Number:
- MFCD30182058
- MOL File:
- 2055024-42-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Azido-PEG3-Sulfone-PEG4-acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0115282 | Azido-PEG3-Sulfone-PEG4-acid ≥98% | 2055024-42-3 | 100mg | $327 | 2026-06-04 | Buy |
| ChemScene | CS-0115282 | Azido-PEG3-Sulfone-PEG4-acid ≥98% | 2055024-42-3 | 250mg | $544 | 2026-06-04 | Buy |
| ChemScene | CS-0115282 | Azido-PEG3-Sulfone-PEG4-acid ≥98% | 2055024-42-3 | 1g | $1402 | 2026-06-04 | Buy |
| BroadPharm | bp-23236 | Azido-PEG3-Sulfone-PEG4-acid 98% | 2055024-42-3 | 100MG | $320 | 2026-05-24 | Buy |
| BroadPharm | bp-23236 | Azido-PEG3-Sulfone-PEG4-acid 98% | 2055024-42-3 | 250MG | $540 | 2026-05-24 | Buy |
Azido-PEG3-Sulfone-PEG4-acid Chemical Properties, Uses, Production
Description
Azido-PEG3-Sulfone-PEG4-acid is a PEG linker containing one azide group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Azido-PEG3-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-Sulfone-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG3-Sulfone-PEG4-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1981 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Aikon International Limited | 17714375163 | hywu@aikonchem.com | China | 9974 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39319 | 58 |
| Shandong fen Boyu Biotechnology Co.,LTD | 13356310019 13356310019; | boyu2024@163.com | China | 3947 | 58 |
View Latest Price from Azido-PEG3-Sulfone-PEG4-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Azido-PEG3-Sulfone-PEG4-acid
2055024-42-3
|
500mg | >95.00% | 500mg | Xian confluore Biological Technology Co., Ltd. |
-
- Azido-PEG3-Sulfone-PEG4-acid
2055024-42-3
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
