ChemicalBook >> CAS DataBase List >>2'-O-Methylcytidine

2'-O-Methylcytidine

2'-O-Methylcytidine structure

CAS No.: 2140-72-9

Chemical Name:: 2'-O-Methylcytidine

Synonyms: 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one;OMe-rC;2'-OMe-C;2'-OMe-rC;2'-OMe-Cr;2'-O-Me-dC;2'-O-Me-rC;2'-OMe Cytidine;2'-OMe-cytidine;2'-Methoxycytidine

CBNumber:: CB9324099

Molecular Formula:: C10H15N3O5

Molecular Weight:: 257.24

MDL Number:: MFCD11519076

MOL File:: 2140-72-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:18

Product description	Number	Pack Size	Price
2'-O-Methylcytidine >98.0%(HPLC)(T)	M2317	200mg	$37
2'-O-Methylcytidine >98.0%(HPLC)(T)	M2317	1g	$137
2'-O-Methylcytidine	296261	300mg	$333
2’-O-MethylCytidine	M294660	5g	$480
2?-O-Methyl-cytidine	18114	50mg	$1400
More product size

Request For Quotation

2'-O-Methylcytidine Properties

Melting point	252-253 C
Boiling point	506.0±60.0 °C(Predicted)
Density	1.68±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility	Soluble in DMSO.
pka	13.37±0.70(Predicted)
form	Powder
color	White to Off-white
PH	4.2
optical activity	70.902° (C=0.01 g/ml, H2O)
λmax	281 (pH 1)；273 (EtOH)
Major Application	pharmaceutical
InChI	InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
InChIKey	RFCQJGFZUQFYRF-ZOQUXTDFSA-N
SMILES	OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OC)[C@@H]1O
CAS DataBase Reference	2140-72-9(CAS DataBase Reference)
FDA UNII	5XD9IH2G27
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-24/25
WGK Germany	3
HS Code	29349990
Storage Class	11 - Combustible Solids

2'-O-Methylcytidine price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M2317	2'-O-Methylcytidine >98.0%(HPLC)(T)	2140-72-9	200mg	$37	2026-03-19	Buy
TCI Chemical	M2317	2'-O-Methylcytidine >98.0%(HPLC)(T)	2140-72-9	1g	$137	2026-03-19	Buy
Usbiological	296261	2'-O-Methylcytidine	2140-72-9	300mg	$333	2021-12-16	Buy
TRC	M294660	2’-O-MethylCytidine	2140-72-9	5g	$480	2021-12-16	Buy
Medical Isotopes, Inc.	18114	2?-O-Methyl-cytidine	2140-72-9	50mg	$1400	2021-12-16	Buy

Product number	Packaging	Price	Buy
M2317	200mg	$37	Buy
M2317	1g	$137	Buy
296261	300mg	$333	Buy
M294660	5g	$480	Buy
18114	50mg	$1400	Buy

2'-O-Methylcytidine Chemical Properties,Uses,Production

Description

2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon, making it an effective viral replication inhibitor. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways and may be able to bind to the response element on DNA, which could inhibit protein synthesis in cancer cells. It is an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.8 μM). It inhibits HCV replication in a replicon assay (IC50 = 21.2 μM).

Chemical Properties

White powder

Uses

2'-O-Methylcytidine is used in the preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.

Uses

Cytidine analog.

Definition

ChEBI: 2'-O-methylcytidine is a methylcytidine.

References

[1] GIOVANNI MIGLIACCIO. Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro.[J]. The Journal of Biological Chemistry, 2003, 278 49: 49164-49170. DOI: 10.1074/jbc.m305041200

2'-O-Methylcytidine synthesis

Synthesis of 2'-O-Methylcytidine from 1,3,5-Tri-O-benzoyl-2-O-methyl-D-ribose

2'-O-Methylcytidine Preparation Products And Raw materials

Raw materials

Preparation Products

3-METHYL URIDINE

2'-O-Methylcytidine Suppliers

Global( 296)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	yunbiochem@126.com	China	321	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29821	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10404	58
Nanjing Baifuli Technology Co., Ltd.	+86-15335185688	sales@unisyn.cn	CHINA	332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Yunbio Tech Co.,Ltd.	58
HANGZHOU LEAP CHEM CO., LTD.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Shenzhen Nexconn Pharmatechs Ltd	58
Nanjing Baifuli Technology Co., Ltd.	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 2'-O-Methylcytidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-24	2'-O-Methylcytidine 2140-72-9	US $0.00 / kg	1kg	99%MIN	20tons	HANGZHOU HAILAN CHEMICAL CO.,LTD.
2025-09-25	2'-O-Methylcytidine 2140-72-9	US $6.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2024-08-07	2'-O-Methylcytidine 2140-72-9	US $0.00 / KG	1KG	98%	300KG per month	Yunbio Tech Co.,Ltd.

2'-O-Methylcytidine
2140-72-9
US $0.00 / kg
99%MIN
HANGZHOU HAILAN CHEMICAL CO.,LTD.

2'-O-Methylcytidine
2140-72-9
US $6.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

2'-O-Methylcytidine
2140-72-9
US $0.00 / KG
98%
Yunbio Tech Co.,Ltd.

2'-O-Methylcytidine Spectrum

2'-O-Methylcytidine(2140-72-9)¹HNMR

2140-72-9(2'-O-Methylcytidine)Related Search:

(Trifluoromethoxy)benzene Anisole Methoxyacetic acid p-Anisidine p-Anisaldehyde

Methoxydiethylborane POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE 4-Methoxybenzoic acid 2'-O-Methyl-N4-Benzoyl-5'-O-DMT-Cytidine (R)-(-)-TETRAHYDROFURFURYL ALCOHOL

(S)-(+)-1-DIMETHYLAMINO-2-PROPANOL 3-Methylcytidine 2''-METHYLCYTIDINE,2'-C-METHYLCYTIDINE 2''-DEOXY-5-METHYLCYTIDINE (5-METHYL-2''-DEOXYCYTIDINE),2'-DEOXY-5-METHYLCYTIDINE N4-BENZOYL-2'-O-METHYLCYTIDINE

2'-O-Methyl-N4-Acetyl-5'-O-DMT-Cytidine 5-Methylcytidine N4-Acetyl-2'-O-Methyl-cytidine

1of4

2'-OMe-C 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one 4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one 2'-OMe Cytidine 4-aMino-1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2-dihydropyriMidin-2-one 2'-O-Methylcytidine, >98.0%(HPLC) 2'-O-Methylcytidine, >=99% 2''-(O-METHYL)-CYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one 2'-O-Methylcytidineanhydrous 2'-O-Methyl-D-cytidine 2'-O-Methylcytidine> 2'-OMe-rC 2'-O-Methylcytidine USP/EP/BP 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2-dihydropyrimidin-2-one 2'-OMe-Cr 2’-O-Methyl cytidine, RNA nucleoside Cm OMe-rC 2'-O-Methylcytidine 2'-OMe-cytidine 2'-O-Me-dC 2'-O-Me-rC Cytidine, 2'-O-methyl- 2'-O-Methyl-d3 Cytidine 2'-Methoxycytidine 2′-0-Methylcytidine 2'-O-Methylcytidine 2′-O-Methylcytidine - [M84857] 2140-72-9 Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs BioChemical Biochemicals and Reagents Bases & Related Reagents Carbohydrates & Derivatives Heterocycles Nucleotides Nucleosides, Nucleotides, Oligonucleotides Biochemicals and Reagents Nucleoside Analogs Nucleosides Modified（deoxy）nucleoside Nucleosides-2'-OMe Nucleosides