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ChemicalBook >> CAS DataBase List >>3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Structure
3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE structure
CAS No.
112192-04-8
Chemical Name:
3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE
Synonyms
Roxindole;RoxindoleHCl;Roxindole [inn];ROXINDOLE HYDROCHLORIDE;1H-Indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-;3-[4-[(3,6-Dihydro-4-phenylpyridin)-1(2H)-yl]butyl]-1H-indol-5-ol;3-[4-(3,6-Dihydro-4-phenylpyridine-1(2H)-yl)butyl]-1H-indole-5-ol;3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE
CBNumber:
CB9330973
Molecular Formula:
C23H26N2O
Molecular Weight:
346.47
MDL Number:
MFCD04038810
MOL File:
112192-04-8.mol
Last updated:2025-09-18 19:10:02
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3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Properties

Melting point >165°C (dec.)
Boiling point 575.7±50.0 °C(Predicted)
Density 1.173±0.06 g/cm3(Predicted)
storage temp. Desiccate at -20°C
solubility DMSO (Slightly), Water (Slightly)
pka 10.15±0.40(Predicted)
form Solid
color Pale Beige to Light Beige
Stability Hygroscopic
FDA UNII 43227SMS0O

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1559 Roxindolehydrochloride ≥98%(HPLC) 112192-04-8 10 $181 2021-12-16 Buy
Tocris 1559 Roxindolehydrochloride ≥98%(HPLC) 112192-04-8 50 $738 2021-12-16 Buy
Usbiological 256504 Roxindole hydrochloride 112192-04-8 10mg $423 2021-12-16 Buy
American Custom Chemicals Corporation API0012443 ROXINDOLE 95.00% 112192-04-8 5MG $503.71 2021-12-16 Buy
Product number Packaging Price Buy
1559 10 $181 Buy
1559 50 $738 Buy
256504 10mg $423 Buy
API0012443 5MG $503.71 Buy

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Roxindole Hydrochloride is a selective and potent presynaptic D-2 dopamine autoreceptor agonist.

Definition

ChEBI: Roxindole is a member of indoles. It has a role as an alpha-adrenergic antagonist and a serotonergic drug.

Biological Activity

Dopamine D 2 autoreceptor agonist, with affinity for D 3 , D 4 and 5-HT 1 receptors (pK i values are 8.55, 8.93, 8.23, 9.42, 6.00 and 7.05 for human D 2 , D 3 , D 4 , 5-HT 1A , 5-HT 1B and 5-HT 1D receptors). Inhibits 5-HT uptake and is antidepressant in vivo .

in vivo

Roxindole inhibits apomorphine-induced climbing in mice and stereotyped behavior in rats with ED50s of 1.4 mg/kg s.c. and 0.65 mg/kg s.c., respectively, and inhibits conditioned avoidance response in rats (ED50=1.5 mg/kg s.c.)[1].
Roxindole (EMD 49980) (1, 3, 10 mg/kg; s.c) inhibits both effects of 8-OH-DPAT (flat body and forepaw treading) in normal rats (male Wistar 200-350g)[3].

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Suppliers

Global( 23)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32431 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53900 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44814 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24989 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Santa Cruz Biotechnology Inc 021-60936350 scbt@scbt.com China 6594 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Aladdin Scientific 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
EMMX Biotechnology LLC 60
Energy Chemical 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Santa Cruz Biotechnology Inc 58

View Lastest Price from 3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Roxindole pictures 2025-09-18 Roxindole
112192-04-8
 US $293.00-987.00 / mg 98.93% 10g TargetMol Chemicals Inc.
  • Roxindole pictures
  • Roxindole
    112192-04-8
  • US $293.00-987.00 / mg
  • 98.93%
  • TargetMol Chemicals Inc.

112192-04-8(3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE)Related Search:

ROXINDOLE MESYLATE 3-(4-(4-PHENYL-1,2,3,6-TETRAHYDRO-1-PYRIDYL)BUTYL)INDOLE, HCL 1,2,3,6-Tetrahydro-4-phenyl-pyridine 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride 3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE
1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE

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3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE ROXINDOLE HYDROCHLORIDE Roxindole RoxindoleHCl 3-[4-(3,6-Dihydro-4-phenylpyridine-1(2H)-yl)butyl]-1H-indole-5-ol 3-[4-[(3,6-Dihydro-4-phenylpyridin)-1(2H)-yl]butyl]-1H-indol-5-ol Roxindole [inn] 1H-Indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]- 112192-04-8 Dopamine receptor