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Clinofibrate

Clinofibrate Structure
Clinofibrate structure
CAS No.
30299-08-2
Chemical Name:
Clinofibrate
Synonyms
S 8527;lipoclin;bis(oxy);CLINOFIBRATE;Clinofibrate >CLINOFIBRATE (S-8527);Clinofibrate USP/EP/BP;2,2'-(cyclohexyliden...;CLINOFIBRATE(FORR&DONLY);bis(2-methylbutanoic acid)
CBNumber:
CB9333525
Molecular Formula:
C28H36O6
Molecular Weight:
468.58
MDL Number:
MFCD00865769
MOL File:
30299-08-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
Clinofibrate >98.0%(HPLC) C3100 200mg $93
Clinofibrate >98.0%(HPLC) C3100 1g $283
Clinofibrate ≥95% 31109 10mg $107
Clinofibrate ≥95% 31109 25mg $240
Clinofibrate ≥95% 31109 50mg $396
More product size
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Clinofibrate Properties

Melting point 143-145°C
Boiling point 498.6°C (rough estimate)
Density 1.1005 (rough estimate)
refractive index 1.4482 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Sligthly)
form Solid
pka 3.00±0.10(Predicted)
color White to Off-White
Merck 14,2357
CAS DataBase Reference 30299-08-2(CAS DataBase Reference)
FDA UNII 0374EZJ8CU

SAFETY

Risk and Safety Statements

RTECS  ES8900000
HS Code  2918.99.4700

Clinofibrate price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C3100 Clinofibrate >98.0%(HPLC) 30299-08-2 200mg $93 2025-07-31 Buy
TCI Chemical C3100 Clinofibrate >98.0%(HPLC) 30299-08-2 1g $283 2025-07-31 Buy
Cayman Chemical 31109 Clinofibrate ≥95% 30299-08-2 10mg $107 2026-04-30 Buy
Cayman Chemical 31109 Clinofibrate ≥95% 30299-08-2 25mg $240 2026-04-30 Buy
Cayman Chemical 31109 Clinofibrate ≥95% 30299-08-2 50mg $396 2026-04-30 Buy
Product number Packaging Price Buy
C3100 200mg $93 Buy
C3100 1g $283 Buy
31109 10mg $107 Buy
31109 25mg $240 Buy
31109 50mg $396 Buy

Clinofibrate Chemical Properties,Uses,Production

Chemical Properties

White Solid

Originator

Lipocrin,Sumitomo,Japan,1981

Uses

Clinofibrate is an antilipemic, used as an anti-atherosclerosis agent.

Definition

ChEBI: Clinofibrate is an organic molecular entity.

Manufacturing Process

Into a mixture of 6.0 g of a bishydroxyphenyl derivative, and 44.0 g of methyl ethyl ketone was added 16.2 g of crushed potassium hydroxide or sodium hydroxide. Chloroform was added dropwise into the above mixture with stirring at 20°C to 80°C, and the resultant mixture was heated for 20 hours under reflux to complete the reaction. Thereafter the reaction mixture was concentrated to give a residue. Into the residue was added water. After cooling, the resultant mixture was treated with activated charcoal and acidified by diluted hydrochloric acid or sulfuric acid to give an oily substance. The oily substance was extracted by ether and the ether solution was contacted with aqueous diluted Na2CO3 solution. The separated aqueous layer was washed with ether, acidified and again extracted with ether. The obtained ester layer was dried over anhydrous sodium sulfate and concentrated to give 1.0 g of a crude product which was purified by recrystallization or chromatography, to give crystals MP 143°C to 146°C (decomp.)

Therapeutic Function

Antihyperlipoproteinemic

References

[1] Patent: CN102816060, 2016, B. Location in patent: Paragraph 0033; 0037

Clinofibrate Preparation Products And Raw materials

Raw materials

2-Butanone Butanoic acid, 2,2'-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl-, 1,1'-diethyl ester Methanol Sodium hydroxide Water

Preparation Products

Clinofibrate Suppliers

Global( 183)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29766 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 sales@amoychem.com China 6361 58
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17339 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-17392587031 1059@dideu.com China 9984 58
AFINE CHEMICALS LIMITED 		+86-571-85134551 +86-18958018566 info@afinechem.com China 15058 58
BOC Sciences 		16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
Supplier Advantage
career henan chemical co 		58
Xiamen AmoyChem Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
SIMAGCHEM CORP 		58
TargetMol Chemicals Inc. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Shaanxi Dideu Medichem Co. Ltd 		58
AFINE CHEMICALS LIMITED 		58
BOC Sciences 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58

View Lastest Price from Clinofibrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Clinofibrate pictures 2026-07-27 Clinofibrate
30299-08-2
 $31.00-48.00 99.50% 10g TargetMol Chemicals Inc.
Clinofibrate pictures 2020-05-12 Clinofibrate
30299-08-2
 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
Clinofibrate pictures 2019-09-02 Clinofibrate
30299-08-2
 $7.00 1KG 99% 1000KG Career Henan Chemical Co
  • Clinofibrate pictures
  • Clinofibrate
    30299-08-2
  • $31.00-48.00
  • 99.50%
  • TargetMol Chemicals Inc.

Clinofibrate Spectrum

Clinofibrate(30299-08-2)1HNMR

30299-08-2(Clinofibrate)Related Search:

Paraquat dichloride Methyl acetate Basic Violet 1 Butyric Acid Methanol
Methyl acrylate Methylparaben Bezafibrate Kresoxim-methyl lifibrate
Acetonitrile Methyl 4,4'-Cyclohexylidenebisphenol 4-TERT-BUTYLPHENOXYACETIC ACID 4,4'-ISOPROPYLIDENEBIS(2-PHENOXYETHANOL)
2-Phenoxybutyric acid (S)-(+)-2-Methylbutyric acid Methylbutyric acid

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CLINOFIBRATE (S-8527) 2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis(2-methylbutyricacid) lipoclin 2,2'-(cyclohexylidenebis(4,1-phenyleneoxy))bis(2-methyl)-butanoic acid CLINOFIBRATE CLINOFIBRATE(FORR&DONLY) 1,1-Bis[4'-(1''-carboxy-1''-methylpropoxy)phenyl]cyclohexane Butanoic acid, 2,2'-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl- S 8527 2,2'-[(1,1-Cyclohexanediyl)bis(4,1-phenyleneoxy)]bis(2-methylbutanoic acid) 2,2'-[Cyclohexylidenebis(4,1-phenyleneoxy)]bis(2-methylbutyric acid) 2,2'-(cyclohexyliden... 2,2,-((cyclohexane-1,1-diylbis(4,1-phenylene))bis(oxy))bis(2-methylbutanoic acid) 2,2'-((Cyclohexane-1,1-diylbis(4,1-phenylene) bis(2-methylbutanoic acid) bis(oxy) 2,2’-(4,4’-cyclohexylidenediphenoxy)-2,2’-dimethyldibutyricacid 2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis-(2-methyl-butyricaci Clinofibrate > 2,2'-(4,4'-Cyclohexylidenediphenoxy)-2,2'-dimethyldibutanoic Acid Clinofibrate USP/EP/BP Clinofibrate (10mM in DMSO) 2,2’-[[Cyclohexane-1,1-diylbis(4,1-phenylene)]bis(oxy)]bis(2-methylbutanoic Acid) 2-(4-{1-[4-(1-carboxy-1-methylpropoxy)phenyl]cyclohexyl}phenoxy)-2-methylbutanoic acid 30299-08-2 30298-08-2 C28H36O6 API Inhibitors Aromatics Intermediates & Fine Chemicals Pharmaceuticals