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ChemicalBook >> CAS DataBase List >>E3 ligase Ligand-Linker Conjugates 13

E3 ligase Ligand-Linker Conjugates 13

E3 ligase Ligand-Linker Conjugates 13 Structure
E3 ligase Ligand-Linker Conjugates 13 structure
CAS No.
2010159-45-0
Chemical Name:
E3 ligase Ligand-Linker Conjugates 13
Synonyms
VH032-PEG2-N3;S)-AHPC-PEG2-N3;(S,R,S)-AHPC-PEG2-azide;VHL Ligand-Linker Conjugates 6;E3 ligase Ligand-Linker Conjugates 13;(S,R,S)-AHPC-PEG2-azide;E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCPEG2N3,Inhibitor,inhibit,(S,R,S)-AHPC-PEG-2-N3,(S,R,S) AHPC PEG2 N3;L-Prolinamide, N-[2-[2-(2-azidoethoxy)ethoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(2S,4R)-1-((S)-2-(2-(2-(2-azidoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-1-((S)-2-(2-(2-(2-Azidoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, Crosslinker?E3 ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader, VH032 conjugate
CBNumber:
CB93386465
Molecular Formula:
C28H39N7O6S
Molecular Weight:
601.72
MDL Number:
MFCD31807300
MOL File:
2010159-45-0.mol
MSDS File:
SDS
Last updated:2026-05-11 16:31:51
Product description Number Pack Size Price
(S,R,S)-AHPC-PEG2-azide 904813 50MG $1340
(S,R,S)-AHPC-PEG2-N3 ≥98% CS-7735 50mg $192
(S,R,S)-AHPC-PEG2-N3 ≥98% CS-7735 100mg $338
(S,R,S)-AHPC-PEG2-N3 ≥98% CS-7735 500mg $1038
(S,R,S)-AHPC-PEG2-N3 ≥98% CS-7735 1g $1558
Request For Quotation

E3 ligase Ligand-Linker Conjugates 13 Properties

storage temp. 2-8°C
form Liquid
color Off-white to yellow
InChIKey SDSUWMZOAFJCPF-OTNCWRBYSA-N
SMILES O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H](C[C@@H](O)C3)N3C([C@H](C(C)(C)C)NC(COCCOCCN=[N+]=[N-])=O)=O
UNSPSC Code 51171641
NACRES NA.22

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

E3 ligase Ligand-Linker Conjugates 13 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 904813 (S,R,S)-AHPC-PEG2-azide 2010159-45-0 50MG $1340 2026-04-30 Buy
ChemScene CS-7735 (S,R,S)-AHPC-PEG2-N3 ≥98% 2010159-45-0 50mg $192 2026-06-04 Buy
ChemScene CS-7735 (S,R,S)-AHPC-PEG2-N3 ≥98% 2010159-45-0 100mg $338 2026-06-04 Buy
ChemScene CS-7735 (S,R,S)-AHPC-PEG2-N3 ≥98% 2010159-45-0 500mg $1038 2026-06-04 Buy
ChemScene CS-7735 (S,R,S)-AHPC-PEG2-N3 ≥98% 2010159-45-0 1g $1558 2026-06-04 Buy
Product number Packaging Price Buy
904813 50MG $1340 Buy
CS-7735 50mg $192 Buy
CS-7735 100mg $338 Buy
CS-7735 500mg $1038 Buy
CS-7735 1g $1558 Buy

E3 ligase Ligand-Linker Conjugates 13 Chemical Properties,Uses,Production

Uses

Protein degrader builiding block (S,R,S)-AHPC-PEG2-azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

reaction suitability

reaction type: click chemistry
reagent type: ligand-linker conjugate

IC 50

VHL

E3 ligase Ligand-Linker Conjugates 13 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 ligase Ligand-Linker Conjugates 13 Suppliers

Global( 24)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 1924344760@confluore.cn China 2997 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
Shanghai Chaolan Chemical Technology Center QQ：65489617 19372819560 Sales@ATKchemical.com China 9627 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4953 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1639 58
Changsha Bono New Materials Technology Co., Ltd. 18191076804 asherw9@hotmail.com China 2373 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49312 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Xian confluore Biological Technology Co., Ltd. 		58
Sigma-Aldrich 80
Shanghai Chaolan Chemical Technology Center 58
Xi'an Confluore Biological Technology Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Changsha Bono New Materials Technology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
Shanghai hongqu biomedical technology co. LTD 58

View Lastest Price from E3 ligase Ligand-Linker Conjugates 13 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S,R,S)-AHPC-PEG2-N3 pictures 2026-05-11 (S,R,S)-AHPC-PEG2-N3
2010159-45-0
 $33.00-106.00 99.33% 10g TargetMol Chemicals Inc.
(S,R,S)-AHPC-PEG2-azide pictures 2025-06-07 (S,R,S)-AHPC-PEG2-azide
2010159-45-0
 100mg >99.00% 100mg Xian confluore Biological Technology Co., Ltd.

E3 ligase Ligand-Linker Conjugates 13 Spectrum

E3 ligase Ligand-Linker Conjugates 13(2010159-45-0)1HNMR

2010159-45-0(E3 ligase Ligand-Linker Conjugates 13)Related Search:

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E3 ligase Ligand-Linker Conjugates 6 E3 Ligase Ligand-Linker Conjugates 19 E3 Ligase Ligand-Linker Conjugates 22 E3 ligase Ligand-Linker Conjugates 11

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E3 ligase Ligand-Linker Conjugates 13 (S,R,S)-AHPC-PEG2-azide VHL Ligand-Linker Conjugates 6 VH032-PEG2-N3 S)-AHPC-PEG2-N3 E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCPEG2N3,Inhibitor,inhibit,(S,R,S)-AHPC-PEG-2-N3,(S,R,S) AHPC PEG2 N3 (2S,4R)-1-((S)-2-(2-(2-(2-Azidoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, Crosslinker?E3 ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader, VH032 conjugate (2S,4R)-1-((S)-2-(2-(2-(2-azidoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide L-Prolinamide, N-[2-[2-(2-azidoethoxy)ethoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- (S,R,S)-AHPC-PEG2-azide 2010159-45-0