EC 1.1.1.1
- CAS No.
- 9031-72-5
- Chemical Name:
- EC 1.1.1.1
- Synonyms
- ADH;Alcohol dehydrogenase;LKADH;HLADH;EC 1.1.1.1;EC: 1.1.1.1;IUB: 1.1.1.1;ADH, Alcohol:;KETOREDUCTASE CB;KETOREDUCTASE CP
- CBNumber:
- CB9358485
- Molecular Formula:
- n.a.
- Molecular Weight:
- 0
- MDL Number:
- MFCD00081305
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| RTECS | SZ5999500 |
|---|---|
| storage temp. | -20°C |
| solubility | H2O: soluble1.0mg/mL, clear to slightly hazy, colorless to faintly yellow |
| form | solution |
| color | slightly beige |
| PH | 7 |
| biological source | Saccharomyces cerevisiae |
| Water Solubility | Soluble in water. |
| Sensitive | Hygroscopic |
| Specific Activity | ≥300units/mg protein |
| Major Application | diagnostic assay manufacturing |
| EPA Substance Registry System | Dehydrogenase, alcohol (9031-72-5) |
| UNSPSC Code | 12352204 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H334-H317 | |||||||||
| Precautionary statements | P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 35079090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
EC 1.1.1.1 price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A7011 | Alcohol Dehydrogenase from Saccharomyces cerevisiae lyophilized powder (contains buffer salts), ≥300?units/mg protein | 9031-72-5 | 7500units | $57.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | A7011 | Alcohol Dehydrogenase from Saccharomyces cerevisiae lyophilized powder (contains buffer salts), ≥300?units/mg protein | 9031-72-5 | 15000Units | $71.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | A7011 | Alcohol Dehydrogenase from Saccharomyces cerevisiae lyophilized powder (contains buffer salts), ≥300?units/mg protein | 9031-72-5 | 30000units | $126 | 2026-04-30 | Buy |
| Sigma-Aldrich | A7011 | Alcohol Dehydrogenase from Saccharomyces cerevisiae lyophilized powder (contains buffer salts), ≥300?units/mg protein | 9031-72-5 | 75000units | $277 | 2026-04-30 | Buy |
| Sigma-Aldrich | A8656 | Alcohol Dehydrogenase from Saccharomyces cerevisiae | 9031-72-5 | 1vial | $144 | 2026-04-30 | Buy |
EC 1.1.1.1 Chemical Properties, Uses, Production
Description
Alcohol dehydrogenases (ADH) (EC 1.1.1.1) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+) to NADH. In humans and many other animals, they serve to break down alcohols that otherwise are toxic, and they also participate in generation of useful aldehyde, ketone, or alcohol groups during biosynthesis of various metabolites. In yeast, plants, and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD+.
Properties
The alcohol dehydrogenases comprise a group of several isozymes that catalyse the oxidation of primary and secondary alcohols to aldehydes and ketones, respectively, and also can catalyse the reverse reaction.In mammals this is a redox (reduction/oxidation) reaction involving the coenzyme nicotinamide adenine dinucleotide (NAD+).
Applications
In biotransformation, alcohol dehydrogenases are often used for the synthesis of enantiomerically pure stereoisomers of chiral alcohols.Often, high chemo- and enantioselectivity can be achieved. In fuel cells, alcohol dehydrogenases can be used to catalyze the breakdown of fuel for an ethanol fuel cell.
Chemical Properties
Off-white lyophilized powder, soluble in water, pI 5.4, optimum pH 8.6-9.0 (ethanol oxidation) or 7.0 (aldehyde reduction). Stability: high concentration of nearly neutral enzyme in pure water can be stable for several days at 5℃, unstable in acidic (pH lower than 6.0) and alkaline (pH greater than 8.5) solution; adding glutathione, cysteine or serum albumin to dilute solution can increase its stability; lyophilized powder containing sucrose and phosphate, stored at 4℃ for six months, the vitality is reduced by 10%; crystal suspension containing phosphate, stored at 4℃ for six months, the vitality is reduced by 40%. Crystallized suspension containing phosphate, 40% reduction in viability for six months at 4°C. Activators include mercaptoethanol, dimercaptosuccinol, cysteine and heavy metal chelators; inhibitors include heavy metals and sulfhydryl reagents. Enzymatic reaction: alcohol + coenzyme I ═ aldehyde or ketone + reduced coenzyme I.
Uses
Alcohol dehydrogenase catalyzes the reaction: RCH2OH +NAD+ RCHO + NADH + H+ It facilitates the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In biotransformation, alcohol dehydrogenases are often used for the synthesis of enantiomerically pure stereoisomers of chiral alcohols.
General Description
This product has been enhanced for energy efficiency and waste prevention when used in fuel cell research.
Biochem/physiol Actions
Alcohol dehydrogenase catalyzes the oxidative conversion of alcohol into aldehyde. It has a homodimeric structure with a co-enzyme binding domain at the C-terminal and an N-terminal catalytic domain. The active site is located at the interdomain cleft. Binding of NAD+ in the active site causes conformational changes which create the binding site for the alcohol substrate.
EC 1.1.1.1 Preparation Products And Raw materials
EC 1.1.1.1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Baoman Biotechnology Co., Ltd. | 021-62130998 | baomanbio@163.com | China | 200 | 55 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from EC 1.1.1.1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | EC 1.1.1.1
9031-72-5
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2022-09-23 | Adh Alcohol Dehydrogenase
9031-72-5
|
$2.00 | 1kg | 98 | 1000kg | Wuhan ShuEr Biology Technology Co.,Ltd | |
 |
2020-03-06 | ALCOHOL DEHYDROGENASE RS1;
9031-72-5
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- EC 1.1.1.1
9031-72-5
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Adh Alcohol Dehydrogenase
9031-72-5
- $2.00
- 98
- Wuhan ShuEr Biology Technology Co.,Ltd
-
- ALCOHOL DEHYDROGENASE RS1;
9031-72-5
- $1.00
- 99%
- Career Henan Chemical Co
