GLIAL DERIVED NEUROTROPHIC FACTOR, HUMAN
- CAS No.
- Chemical Name:
- GLIAL DERIVED NEUROTROPHIC FACTOR, HUMAN
- Synonyms
- GDNF;RHGDNF;HUMAN GDNF;GDNF HUMAN;HUMAN ATF-1;REC GDNF (HUMAN);REC ATF-1 (HUMAN);RECOMBINANT HUMAN GDNF;Human GDNF Protein, Gly & Pro Tag;HUMAN GLIAL-DERIVED NEUROTROPHIC FACTOR
- CBNumber:
- CB9361171
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00285867
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| GDNF human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC) | SRP3309 | 10μG | $459 |
| Glial Cell Line-derived Neurotrophic Factor human recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE) | G1777 | 10μG | $225 |
| GDNF | 383059 | 96Tests | $729 |
| GDNF | 383058 | 96Tests | $729 |
| GDNF | 383057 | 96Tests | $729 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
GLIAL DERIVED NEUROTROPHIC FACTOR, HUMAN price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3309 | GDNF human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC) | 10μG | $459 | 2025-07-31 | Buy | |
| Sigma-Aldrich | G1777 | Glial Cell Line-derived Neurotrophic Factor human recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE) | 10μG | $225 | 2025-07-31 | Buy | |
| Usbiological | 383059 | GDNF | 96Tests | $729 | 2021-12-16 | Buy | |
| Usbiological | 383058 | GDNF | 96Tests | $729 | 2021-12-16 | Buy | |
| Usbiological | 383057 | GDNF | 96Tests | $729 | 2021-12-16 | Buy |
GLIAL DERIVED NEUROTROPHIC FACTOR, HUMAN Chemical Properties,Uses,Production
Uses
Glial cell line-derived neurotrophic factor human (GDNF) has been used as a component in the neurobasal medium for neural differentiation. It has also been used for self-renewal, expansion and differentiation of?spermatogonial stem cells (SSCs).
General Description
Glial cell line-derived neurotrophic factor (GDNF) human gene is located on human chromosome 5p13.2.
Biochem/physiol Actions
Glial Cell Line-Derived Neurotrophic Factor is a member of the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF is founding member of the GDNF family of ligands, which to date include GDNF, neurturin (NTN), persephin (PSP) and artemin (ART). GDNF is a glycosylated disulfide-linked homodimeric protein of ~15 kDa. Mature rat and human GDNF share ~93% sequence homology, with strong species cross-reactivity. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRα (α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival and morphological differentiation of midbrain neurons. Using the Parkinson′s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. GDNF promotes survival of various neuronal cells in central and peripheral nervous systems and different stages of development, including motoneurons, midbrain dopaminergic neurons, Purkinje cells and sympathetic neurons. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. In addition, exogenously applied GDNF has been shown to rescue damaged facial motor neurons in vivo.
GLIAL DERIVED NEUROTROPHIC FACTOR, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
GLIAL DERIVED NEUROTROPHIC FACTOR, HUMAN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15402 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 17801761073 | 3193328036@qq.com | China | 29761 | 68 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 | 3193328036@qq.com | China | 6338 | 68 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19103 | 58 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821 | sales@klbio.cn | China | 9621 | 58 |
| Absin Bioscience Inc. | 021-38015121 18438616290 | lanwu@univ-bio.com | China | 24731 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10308 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 19301387927 19301387927 | yh-wang@univ-bio.com | China | 25006 | 58 |
