2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
- CAS No.
- 115029-23-7
- Chemical Name:
- 2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
- Synonyms
- RARECHEM AL BO 0633;2-Fluoro-5-trifluoromethylbenz;à,à,à,6-tetrafluoro-m-toluic acid;2-fluoro-5-(trifluoromethyl)benzoic;2-FLUORO-5-TRIFLUOROMETHYLBENZIOC ACID;2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID;2-Fluoro-5-(trifluoromethyl)benzoicacid98%;2-Fluoro-5-(trifluoromethyl)benzoicAcid>Benzoic acid, 2-fluoro-5-(trifluoromethyl)-;2-Fluoro-5-(trifluoromethyl)benzoic acid 98%
- CBNumber:
- CB9397309
- Molecular Formula:
- C8H4F4O2
- Molecular Weight:
- 208.11
- MDL Number:
- MFCD00061292
- MOL File:
- 115029-23-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Fluoro-5-(trifluoromethyl)benzoic acid 98% | 455253 | 5g | $50.6 |
| 2-Fluoro-5-(trifluoromethyl)benzoic Acid >98.0%(GC)(T) | F0620 | 1g | $25 |
| 2-Fluoro-5-(trifluoromethyl)benzoic Acid >98.0%(GC)(T) | F0620 | 5g | $72 |
| 2-Fluoro-5-(trifluoromethyl)benzoic acid Asreported | 276760 | 10g | $352 |
| 2-Fluoro-5-(trifluoromethyl)benzoic acid Asreported | 276760 | 25g | $485 |
| More product size | |||
| Melting point | 100-103 °C (lit.) |
|---|---|
| Boiling point | 236℃ |
| Density | 1.489 |
| Flash point | 96℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), |
| pka | 2.84±0.10(Predicted) |
| form | Solid |
| color | Off-White to Pale Beige |
| BRN | 5813056 |
| InChI | InChI=1S/C8H4F4O2/c9-6-2-1-4(8(10,11)12)3-5(6)7(13)14/h1-3H,(H,13,14) |
| InChIKey | LIFKXWNFWIUMJT-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC(C(F)(F)F)=CC=C1F |
| CAS DataBase Reference | 115029-23-7(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID price More Price(89)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 455253 | 2-Fluoro-5-(trifluoromethyl)benzoic acid 98% | 115029-23-7 | 5g | $50.6 | 2023-06-20 | Buy |
| TCI Chemical | F0620 | 2-Fluoro-5-(trifluoromethyl)benzoic Acid >98.0%(GC)(T) | 115029-23-7 | 1g | $25 | 2026-04-30 | Buy |
| TCI Chemical | F0620 | 2-Fluoro-5-(trifluoromethyl)benzoic Acid >98.0%(GC)(T) | 115029-23-7 | 5g | $72 | 2026-04-30 | Buy |
| Usbiological | 276760 | 2-Fluoro-5-(trifluoromethyl)benzoic acid Asreported | 115029-23-7 | 10g | $352 | 2026-06-03 | Buy |
| Usbiological | 276760 | 2-Fluoro-5-(trifluoromethyl)benzoic acid Asreported | 115029-23-7 | 25g | $485 | 2026-06-03 | Buy |
2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties,Uses,Production
Chemical Properties
White to off-white powder
Synthesis Reference(s)
Tetrahedron Letters, 33, p. 7495, 1992 DOI: 10.1016/S0040-4039(00)60805-5
Synthesis
402-44-8
115029-23-7
General procedure for the synthesis of 2-fluoro-5-trifluoromethylbenzoic acid from 4-fluorobenzotrifluoride: 99 g (0.6 mol) of 4-fluorobenzotrifluoride was dissolved in 750 ml of tetrahydrofuran at -60 °C and protected by nitrogen, and 256 ml (0.64 mol) of a 2.5 M butyl lithium hexane solution was added slowly dropwise over a controlled period of time. The reaction mixture was stirred continuously at -60 °C to -70 °C for 4 h and subsequently poured into a large excess of dry ice. after 15 min, the excess dry ice was evaporated by external heating and the solvent was removed by rotary evaporator. The residue was dissolved in 500 ml of water, 30 ml of 1N sodium hydroxide solution was added and washed with 2 x 300 ml of ethyl acetate. The aqueous phase was acidified with concentrated hydrochloric acid and then extracted with 2 x 300 ml ethyl acetate. The organic phases were combined and washed sequentially with 500 ml of water and 300 ml of saturated saline, dried over anhydrous sodium sulfate and concentrated by rotary evaporation. The crude product was recrystallized by hexane to give 80 g of white analytically pure crystals with 64% yield and melting point of 205°C. The product was extracted with 500 ml of water and 300 ml of saturated saline. Elemental analysis results (C8H4O2F4): calculated value C 46.17%, H 1.94%; measured value C 46.16%, H 1.89%.
References
[1] Patent: US4705853, 1987, A
[2] Patent: US5304532, 1994, A
2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 923 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
View Lastest Price from 2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-05 | 2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
115029-23-7
|
$420.00 | 1KG | 98% | 20 tons | Speranza Chemical Co., Ltd. | |
 |
2025-04-04 | 2-Fluoro-5-Trifluoromethylbenzoic Acid
115029-23-7
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-07-14 | 2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
115029-23-7
|
$8.80 | 1KG | 97%-99% | 100kg | Career Henan Chemical Co |
-
- 2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
115029-23-7
- $420.00
- 98%
- Speranza Chemical Co., Ltd.
-
- 2-Fluoro-5-Trifluoromethylbenzoic Acid
115029-23-7
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
115029-23-7
- $8.80
- 97%-99%
- Career Henan Chemical Co
115029-23-7(2-FLUORO-5-(TRIFLUOROMETHYL)BENZOIC ACID)Related Search:
1of4
