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Mandelic acid

Mandelic acid Structure
Mandelic acid structure
CAS No.
611-71-2
Chemical Name:
Mandelic acid
Synonyms
D-MANDELIC ACID;(R)-MANDELIC ACID;(R)-(-)-MANDELIC ACID;(R)-2-HYDROXY-2-PHENYLACETIC ACID;2-Hydroxy-2-phenylacetic acid;D-(-)-MANDELIC ACID;(R)-(-)-2-MANDELIC ACID;(R)-(-)-mandelic;(-)-Mandelic acid;(-)-D-MANDELIC ACID
CBNumber:
CB9411418
Molecular Formula:
C8H8O3
Molecular Weight:
152.15
MDL Number:
MFCD00064251
MOL File:
611-71-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:19:37
Product description Number Pack Size Price
Sertraline impurity E European Pharmacopoeia (EP) Reference Standard Y0001285 20 mg $167
(R)-(-)-Mandelic acid for resolution of racemates for synthesis 8.06914 25g $92.4
(R)-(-)-Mandelic acid for resolution of racemates for synthesis 8.06914 100g $178
(R)-(?)-Mandelic acid ReagentPlus , ≥99% 154210 5g $42.3
(R)-(?)-Mandelic acid ReagentPlus , ≥99% 154210 25g $120
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Mandelic acid Properties

Melting point 131-133 °C(lit.)
alpha -150 º (c=2.5, H2O)
Boiling point 214.6°C (rough estimate)
Density 1.1677 (rough estimate)
bulk density 670kg/m3
refractive index -153.5 ° (C=1, H2O)
Flash point >190℃
storage temp. Store below +30°C.
solubility 109.8g/l soluble
form Crystalline Powder, Crystals or Flakes
pka 3.37(at 25℃)
color White to slightly yellow-beige
PH 3.34(1 mM solution);2.75(10 mM solution);2.22(100 mM solution);
optical activity [α]25/D 151°, c = 1 in ethanol
Water Solubility It is partly soluble in water, freely soluble in isopropyl and ethyl alcohol.
Sensitive Light Sensitive
BRN 2691094
Stability Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents.
InChI 1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)/t7-/m1/s1
InChIKey IWYDHOAUDWTVEP-SSDOTTSWSA-N
SMILES O[C@@H](C(O)=O)c1ccccc1
LogP 0.550 (est)
CAS DataBase Reference 611-71-2(CAS DataBase Reference)
FDA UNII PPL7YW1M9W
ATC code B05CA06,J01XX06
EPA Substance Registry System Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)- (611-71-2)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  41-36/37/38
Safety Statements  22-24/25-36-26-39-37/39
WGK Germany  1
Hazard Note  Irritant/Light Sensitive
TSCA  TSCA listed
HS Code  29181980
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Dam. 1
Toxicity LD50 orally in Rabbit: 5000 mg/kg
REACH Registrations Active
NFPA 704
1
2 0

Mandelic acid price More Price(114)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001285 Sertraline impurity E European Pharmacopoeia (EP) Reference Standard 611-71-2 20 mg $167 2026-04-30 Buy
Sigma-Aldrich 8.06914 (R)-(-)-Mandelic acid for resolution of racemates for synthesis 611-71-2 25g $92.4 2026-04-30 Buy
Sigma-Aldrich 8.06914 (R)-(-)-Mandelic acid for resolution of racemates for synthesis 611-71-2 100g $178 2026-04-30 Buy
Sigma-Aldrich 154210 (R)-(?)-Mandelic acid ReagentPlus , ≥99% 611-71-2 5g $42.3 2026-04-30 Buy
Sigma-Aldrich 154210 (R)-(?)-Mandelic acid ReagentPlus , ≥99% 611-71-2 25g $120 2026-04-30 Buy
Product number Packaging Price Buy
Y0001285 20 mg $167 Buy
8.06914 25g $92.4 Buy
8.06914 100g $178 Buy
154210 5g $42.3 Buy
154210 25g $120 Buy

Mandelic acid Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

Antiseptic (urinary).

Uses

(R)-(-)-Mandelic acid, is used as a antiseptic ingredient particularly against urinary tract infections.Mandelic acid and its derivatives are used to apply the dual activities as an antibacterial agent and as an antiaging agent. It is used as an intermediate for the synthesis of target molecules for other applications.

Uses

(R)-()-Mandelic acid can be used:

  • As a chiral acid in the separation of diastereomeric salts for the synthesis of chiral pyridoindole based building block.
  • In the study of chiral acid selectivity of poly(3,4-ethylenedioxythiophene) (PEDOT) based chiral conductingpolymers.

Definition

ChEBI: (R)-mandelic acid is the (R)-enantiomer of mandelic acid. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a (R)-mandelate. It is an enantiomer of a (S)-mandelic acid.

Synthesis Reference(s)

The Journal of Organic Chemistry, 33, p. 2565, 1968 DOI: 10.1021/jo01270a105
Synthetic Communications, 18, p. 2141, 1988 DOI: 10.1080/00397918808068285

General Description

(R)-(-)-Mandelic acid, a chiral resolving agent, is also used as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. It can be synthesized from (R,S)-mandelonitrile with high yield and enantioselectivity using nitrilase enzyme.

Flammability and Explosibility

Non flammable

Purification Methods

Purify the mandelic acids by recrystallisation from H2O, *C6H6 or CHCl3. [Roger J Chem Soc 2168 1932,Jamison & Turner J Chem Soc 611 1942.] They have solubilities in H2O of ca 11% at 25o. [Banks & Davies J Chem Soc 73 1938.] The S-benzylisothiuronium salts has m 180o (from H2O) and [] D 25 (+) and (-) 57o (c20, EtOH) [El Masri et al. Biochem J 68 199 1958]. [Beilstein 10 IV 564.]

Mandelic acid Preparation Products And Raw materials

Raw materials

(S)-(+)-O-Acetyl-L-mandelic acid Vinyl acetate

Preparation Products

1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4R)-(9CI) (R)-3-Amino-1-(3-(Trifluoromethyl)-5,6-Dihydro-[1,2,4] Triazolo[4,3-A]Pyrazin-7(8H)-Yl)-4-(2,4,5-Trifluorophenyl) Butan-1-One Mandelate(Sgn06M) (R)-5-phenyl-1,3-dioxolane-2,4-dione (R)-2-Hydroxy-2-phenylacetohydrazide (R)-2-tert-butyl-3-Methyl-4-oxoiMidazolidin-1-iuM (R)-2-hydroxy-2-phenylacetate
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate

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Mandelic acid Suppliers

Global( 802)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Toachem Chemical Co.,Ltd
+8618311365218 sales@toachem.com China 205 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5228 58
Firsky International Trade (Wuhan) Co., Ltd 		+8615387054039 admin@firsky-cn.com China 427 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858 daisy@anhuiruihan.com China 973 58
Hebei Jingbo New Material Technology Co., Ltd 		+8619931165850 hbjbtech@163.com China 1000 58
Chongqing Zhihe Biopharmaceutical Co., Ltd. 		+8618580541567 sales@zhswyy.com China 259 58
BINBO BIOLOGICAL CO.,LTD 		+8618629063126 info@binbobiological.com China 477 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3692 58
Supplier Advantage
Beijing Toachem Chemical Co.,Ltd
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Firsky International Trade (Wuhan) Co., Ltd 		58
Anhui Ruihan Technology Co., Ltd 		58
Hebei Jingbo New Material Technology Co., Ltd 		58
Chongqing Zhihe Biopharmaceutical Co., Ltd. 		58
BINBO BIOLOGICAL CO.,LTD 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58

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View Lastest Price from Mandelic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mandelic acid pictures 2026-06-16 Mandelic acid
611-71-2
 0.99 RongNa Biotechnology Co.,Ltd
Mandelic Acid pictures 2026-05-28 Mandelic Acid
611-71-2
 $10.00 1kg 98% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
Mandelic acid pictures 2026-05-22 Mandelic acid
611-71-2
 1kg 99.8% 1000 kg BINBO BIOLOGICAL CO.,LTD
  • Mandelic Acid pictures
  • Mandelic Acid
    611-71-2
  • $10.00
  • 98%
  • Hebei Chuanghai Biotechnology Co,.LTD

Mandelic acid Spectrum

Mandelic acid(611-71-2)MSMandelic acid(611-71-2)1HNMRMandelic acid(611-71-2)IR1Mandelic acid(611-71-2)IR2Mandelic acid(611-71-2)Raman

611-71-2(Mandelic acid)Related Search:

PHENYL VALERATE Hyaluronic acid 4-Chloromandelic acid Ethyl 2-(Chlorosulfonyl)acetate Folic acid
Glycolic acid CHLOROPHOSPHONAZO III Phenylboronic acid 5-Pyrazolecarboxylic acid Citric acid
Ascoric Acid Benactyzine Flurenol-butyl 3-Quinuclidinyl benzilate (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
(S)-(+)-Mandelic acid 2-Chloromandelic acid Acetic anhydride

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(R)-(-)-AMYGDALIC ACID (R)-ALPHA-HYDROXYPHENYLACETIC ACID R-(-)-ALPHA-HYDROXYPHENYLACETIC ACID D-ALPHA-HYDROXYPHENYLACETIC ACID D-A-HYDROXYPHENYLACETIC ACID D-2-HYDROXY-PHENYLACETIC ACID D-(-)-AMYGDALIC ACID D-AMYGDALIC ACID D-PHENYLGLYCOLIC ACID (-)-D-MANDELIC ACID L-2-hydroxy-2-phenylacetic acid D(-)-MANDELIC ACID FOR RESOLUTION & (R)-(-)-MANDELIC ACID, 99+% (R)-(-)-MANDELIC ACID, 98% (99% EE/GLC) (R)-(-)-MANDELIC ACID 99% D-(-)-α-Hydroxybenzeneacetic acid ALPHAR-HYDROXY-BENZENEACETIC ACID D-Mandelic acid or R-(-)Mandelic acid Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)- (r)-(-)-à-hydroxyphenylacetic acid D-mandelic acid(R-mandelic acid) (R)-alpha-Hydrophenylacetic acid D-(-)-Mandelic acid 98% L-2-Hydroxy-2-phenylessigsure D-minus-mandelic acid sigma grade [R,(-)]-α-Hydroxybenzeneacetic acid D-()-Mandelic acid,(R)-α-Hydroxyphenylacetic acid (R)-(-)-Mandelic acid, ChiPros\(tm, 99+% ee 99+% )-Mandel (R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-Hydroxy(phenyl)ethanoic acid, D-(-)-Phenylglycolic acid (R)-Alfa-hydroxyphenylacetic acid (R)-()-Mandel (R)-(-)-Mandelic acid, 99% 25GR (R)-(-)-Mandelic acid, 98% e.e. (R)-(-)-MANDELIC ACID FOR RESOLUTION OF (R)-2-Phenylglycolic acid (R)-alpha-Hydroxy-benzeneacetic acid Sertraline EP IMpurity E (R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-2-Hydroxy-2-phenylethanoic acid, D-(-)-Phenylglycolic acid (R)-(-)-Mandelic acid, ChiPros 99+%, ee 99+% D-MANDELIC ACID extrapure (2R)-2-Hydroxy-2-phenylacetic acid (R)-a-Hydroxybenzeneacetic acid (R)-a-Hydroxyphenylacetic acid D-2-Phenylglycolic acid (R)-(-)-MANDELIC ACID: CHIPROS 99%, EE 99% 2-Phenylglycolic acid a-Hydroxy-benzeneacetic acid alpha-Hydroxyphenylacetic acid Hydroxy(phenyl)acetic acid R-Mandelic acid D-Mandelic acid (R)-mandelate 2R)-(-)-Hydroxybenzeneacetic Acid Sertraline Impurity 5（Sertraline EP Impurity E） Benzeneaceticacid, a-hydroxy-, (aR)- (R)-(-)-Mandelic acid ReagentPlus(R), >=99% Sertraline impurity E (R)-(-)-Mandelic acid Vetec(TM) reagent grade, 98%